Navigation Links
UMD Researcher Helps Arm the Immune System to Fight Cancer
Date:1/7/2014

COLLEGE PARK, Md., Jan. 7, 2014 /PRNewswire-USNewswire/ -- In 2004, a form of cancer known as neuroblastoma claimed the life of Alexandra (Alex) Scott, a little girl who gained national attention for using her lemonade stand to raise money for cancer research. Now, the organization established in her memory, the Alex's Lemonade Stand Foundation (ALSF), has awarded University of Maryland (UMD) A. James Clark School of Engineering Assistant Professor Christopher M. Jewell a three-year, $375,000 research grant to support the pre-clinical development of a cancer vaccine technology that could give children like Alex a better chance to have a long and healthy life.

Neuroblastoma, the third most common pediatric cancer, causes nerve cells to turn into tumors. The prototype vaccine uses a unique combination of nanotechnology and immunology to "raise an army" of tumor-hunting immune cells, equip them to attack neuroblastoma, and leave them ready to reactivate if the cancer returns.

The lymph nodes are the body's immune system "command centers," packed with different types of immune cells. Each cell is equipped with a protein that responds to a particular disease or infection. Fragments of viruses, bacteria, and tumors collected in the lymph nodes are presented to these cells as antigens, molecules that provoke a response to a specific threat. When an immune cell encounters an antigen it is designed to respond to, the immune cell "activates" and multiplies. These cells are then released into the blood and tissue to hunt their specific pathogens.

One type of activated immune cell, the central memory T cell, is particularly effective at infiltrating tumors. These cells start life as ordinary, inactive T cells in the lymph nodes that have the potential to become one of a number of active T cell types. Jewell's goal is to enhance the immune system's natural response by enco
'/>"/>

SOURCE A. James Clark School of Engineering
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. ideaPoint, Inc. Announces Launch of Multi-Sponsor Portal Providing Researchers Opportunity to Request Access to Clinical Data from Five Global Study Sponsors
2. Regado Biosciences, Inc. Adds World-Class Interventional Cardiologist and Researcher to Medical Advisory Board
3. Researchers Use CT and 3-D Printers to Recreate Dinosaur Fossils
4. Nova Southeastern University Researchers Receive $4.1 Million Grant from Department of Defense to Investigate Gulf War Illness
5. Transparency Life Sciences Partners With Oncology Researchers At Icahn School Of Medicine At Mount Sinai To Assess Metformin In Prostate Cancer
6. FIU Researcher Advances Retinal Implant That Could Restore Sight For The Blind
7. PRA Staff Named Finalists in Clinical Researcher of the Year Competition
8. Kaiser Permanente Researchers Honored for Drug Therapy Study
9. Pharmaceutical Giants Back Researchers in Unique US Competition
10. A Young Researcher from Italy Wins this Years "Basel Declaration Award for Education in Animal Research"
11. Northwestern Medicine Researchers Investigate New Stent Technology to Treat Coronary Artery Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... Nov. 20, 2014 /CNW Telbec/ - KLOX Technologies Inc. ... following appointments: Todd Martensen ... newly created role of Chief Commercial Officer, to oversee ... topical photoconverter gel for the treatment of chronic and ... wounds, recently approved in Europe . ...
(Date:11/21/2014)... 2014 Michael DeMarco (42) erinnert ... 14. Februar 2014 zugetragen hat. Seine Tochter Aly Demarco ... Video - http://youtu.be/5cVoMCe0uiE ... morgendliches Training zu machen", erzählt Michael DeMarco . ... begeisterte Anhänger der CrossFit-Trainingsmethode. Ich war auf dem ...
(Date:11/21/2014)... , Nov. 20, 2014   Coqui RadioPharmaceuticals ... the first U.S. commercial producer of Molybdenum-99 (Mo-99), is ... with INVAP to design its Medical Isotope ... Mo-99 is the parent isotope of Technetium-99, which ... worldwide. In 2012, Congress passed legislation making it a ...
Breaking Medicine Technology:KLOX Technologies announces executive appointments 2KLOX Technologies announces executive appointments 3KLOX Technologies announces executive appointments 4Tochter rettet Vater durch Herz-Lungen-Wiederbelebung vor plötzlichem Herztod 2Tochter rettet Vater durch Herz-Lungen-Wiederbelebung vor plötzlichem Herztod 3Coqui RadioPharmaceuticals Inks Deal With INVAP 2
... by March of Dimes Grantee Offers Hope for Treatment ... new gene-based,technique has successfully prevented a rare craniofacial birth ... the same disorder, according,to new research funded in part ... is being published in the journal Nature Medicine,demonstrates the ...
... /Xinhua-PRNewswire-FirstCall/ -- Lotus Pharmaceuticals,Inc. (OTC Bulletin Board: ... in the People,s Republic of China ("PRC"), ... in the development of,isosorbide mononitrate sustained release ... and treatment of angina., Based on ...
Cached Medicine Technology:Molecular Therapy Succeeds in Preventing Craniofacial Birth Defect in Mice 2Lotus Pharmaceuticals, Inc. Achieves Significant Milestones in the Development of Isosorbide Mononitrate Sustained Release Tablets 2Lotus Pharmaceuticals, Inc. Achieves Significant Milestones in the Development of Isosorbide Mononitrate Sustained Release Tablets 3
(Date:11/22/2014)... 22, 2014 A petition seeking a ... ) in minimally-invasive hysterectomies and fibroid removal surgeries ... end of October, Bernstein Liebhard LLP reports. According ... of November 21st, 2014. That represents an increase of ... signed on to the campaign.* , The campaign to ...
(Date:11/22/2014)... -- The wide variety and complexity of foods served ... with food allergies, an expert warns. "Every person ... food allergies that it can be really difficult to ... director of allergy and clinical immunology at Wake Forest ... "If you know you have food allergies, caution ...
(Date:11/22/2014)... New York, New York (PRWEB) November 22, 2014 ... been filed on behalf of patients who allegedly developed ... move forward in the federal multidistrict litigation now underway ... Liebhard LLP reports. According to court documents, the litigation ... at 10:00 a.m. The Court has directed Lead Counsel ...
(Date:11/22/2014)... Hastings and Hastings, a discount accident attorney in ... with the option of leaving an online review using ... and easy to navigate website that has recently been ... allows clients to research the Hastings and Hastings law ... when retaining an attorney. Those who have been injured ...
(Date:11/22/2014)... (PRWEB) November 22, 2014 Forbes ... are pleased to announce that Ashley Lombardo and ... #PayItForward contest. , Ms. Lombardo entered friend Candy ... Innovations. She wrote of how her friend is courageously ... as a single mom. Despite medical bills piling up ...
Breaking Medicine News(10 mins):Health News:Power Morcellator Petition Gains More than 450 Signatures Since October, Bernstein Liebhard LLP Reports 2Health News:Power Morcellator Petition Gains More than 450 Signatures Since October, Bernstein Liebhard LLP Reports 3Health News:Power Morcellator Petition Gains More than 450 Signatures Since October, Bernstein Liebhard LLP Reports 4Health News:'Tis the Season of Challenges for Those With Food Allergies 2Health News:Lipitor Lawsuit Conference Scheduled for December, Bernstein Liebhard LLP Reports 2Health News:Lipitor Lawsuit Conference Scheduled for December, Bernstein Liebhard LLP Reports 3Health News:Hastings and Hastings Announces Providing Clients with the Option of Leaving an Online Review Using Google + 2Health News:Hastings and Hastings Announces Providing Clients with the Option of Leaving an Online Review Using Google + 3Health News:Forbes Living TV Announces Winner of Thanksgiving #PayItForward Contest 2
... at the University of Southern California have pinned down ... survival trait: our ability to comprehend a sceneeven one ... The key is to process the interacting objects ... according to corresponding author Irving Biederman, professor of psychology ...
... -- Newly diagnosed cancer patients frequently face hurdles in ... to new research from the Perelman School of Medicine ... Saturday, June 4 at the 2011 annual meeting of ... with private health insurance had difficulty scheduling an appointment, ...
... kidney cancer is diagnosed in nearly 60,000 people in ... remove the affected kidney, but this procedure can be ... health problems. Unfortunately, the prognosis of kidney cancer patients ... removed and evaluated. Now, researchers at Fox Chase ...
... June 1 (HealthDay News) -- Boys and girls diagnosed ... of developing a substance abuse problem -- including cigarettes, ... which is one of the largest set of longitudinal ... association between ADHD and substance abuse found in several ...
... effect of a common anticancer drug Cisplatin is ... has some severe side effects in normal tissues, in particular ... this toxicity could identify targets for drugs that could be ... In this context, a team of researchers, led by Zheng ...
... , WEDNESDAY, June 1 (HealthDay News) -- Although the ... Swedish researchers have found that people who had them taken ... slightly greater risk of an early heart attack. ... the tonsils in the body,s immune system with the increased ...
Cached Medicine News:Health News:USC study locates the source of key brain function 2Health News:Two-thirds of newly diagnosed cancer patients unable to obtain oncology appointments 2Health News:Lymphocyte count indicates the prognosis of patients with renal cell carcinoma 2Health News:Children With ADHD More Prone to Substance Abuse: Study 2Health News:JCI online early table of contents: June 1, 2011 2Health News:JCI online early table of contents: June 1, 2011 3Health News:JCI online early table of contents: June 1, 2011 4Health News:JCI online early table of contents: June 1, 2011 5Health News:JCI online early table of contents: June 1, 2011 6Health News:JCI online early table of contents: June 1, 2011 7Health News:JCI online early table of contents: June 1, 2011 8Health News:Can Removing Tonsils, Appendix Boost Early Heart Attack Risk? 2
... offers a comprehensive array of features and ... and neonate patients, to magnetic resonance imaging ... the first MR monitor designed to meet ... patient monitoring. The new monitor is also ...
... InstaTest AFP is an immunochromatographic in vitro ... (AFP) in human serum. AFP is a ... to 74,000 D. Its normal concentration in ... are associated with hepatoma and ovarian, testicular ...
... simple and flexible solution. The Coag-A-Mate ... design, but offers full automation and ... high-volume systems. It is an easy ... also be used as a back-up ...
... is a fully automated open random ... and immunological, latex based coagulation tests. ... 5-position racks as sample carrier offers ... up to 70 reagents on-board with ...
Medicine Products: