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U.S. Navy and U.S. Army to Develop Dengue DNA Vaccine Formulated With Vical's Vaxfectin(R) Adjuvant
Date:11/6/2008

The Infectious Diseases Directorate conducts research on infectious diseases that are considered to be significant threats to deployed sailors, marines, soldiers, and airmen. The primary focus of the Viral Diseases Division is on the development of a vaccine to prevent dengue fever, with a major emphasis on novel vaccine technologies and adjuvants.

About Vical

Vical researches and develops biopharmaceutical products based on its patented DNA delivery technologies for the prevention and treatment of serious or life-threatening diseases. Potential applications of the company's DNA delivery technology include DNA vaccines for infectious diseases or cancer, in which the expressed protein is an immunogen; cancer immunotherapeutics, in which the expressed protein is an immune system stimulant; and cardiovascular therapies, in which the expressed protein is an angiogenic growth factor. The company is developing certain infectious disease vaccines and cancer therapeutics internally. In addition, the company collaborates with major pharmaceutical companies and biotechnology companies that give it access to complementary technologies or greater resources. These strategic partnerships provide the company with mutually beneficial opportunities to expand its product pipeline and address significant unmet medical needs. Additional information on Vical is available at http://www.vical.com.

This press release contains forward-looking statements subject to risks and uncertainties that could cause actual results to differ materially from those projected. Forward-looking statements include statements about the NMRC's, the USAMMDA's and the WRAIR's plans for a continued development of a DNA vaccine for dengue, and the potential effect of the company's Vaxfectin(R) adjuvant on vaccine performance. Risks and uncertainties include whether the NMRC, WRAIR, USAMMDA, Vical or others will continue development of the dengue
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