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U.S. Market for Orthopedic Biomaterials 2012
Date:7/16/2012

NEW YORK, July 16, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

U.S. Market for Orthopedic Biomaterials 2012

http://www.reportlinker.com/p0851579/US-Market-for-Orthopedic-Biomaterials-2012.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Biomaterial

The 2011 figures in the orthopedic biomaterials market show great promise for future performance of the orthopedic biomaterials market. To date there has been a multitude of products introduced to the market, with some becoming spectacular successes. Future growth for this market will be a result of continued improvements in product technology to meet the needs of patients as well as changes in healthcare reform and reimbursement. This comprehensive report covers a number of disciplines, including spinal surgery, sports medicine, tissue donation, and biotechnology. In each segment of this report, current market conditions are thoroughly examined and the behavior of each sub-segment over the forecast period is critically analyzed and cross-verified.

 

The Orthopedic biomaterials market includes:

 

• bone graft substitutes,

• growth factors,

• machined allografts,

• hyaluronic acid viscosupplementation,

• resorbable fixation devices,

• tendon grafts,

• cartilage repair,

• platelet and bone marrow concentration,

• orthopedic stem cells and

• emerging technologies

 

This report provides a comprehensive and detailed analysis of market revenues by device type, market forecasts through 2018, unit sales, average selling prices, market drivers and limiters and a detailed competitive analysis, including manufacturer market shares and product portfolios. This is an executive summary only, the full report is also available for purchase.

 

TABLE OF CONTENTS...I

LIST OF FIGURES...X

LIST OF CHARTS... XVI

EXECUTIVE SUMMARY... 1

1.1 U.S. MARKET FOR ORTHOPEDIC BIOMATERIALS . 1

1.2 ORTHOPEDIC BIOMATERIAL MARKET GROWTH RATES... 2

1.3 BONE GRAFT SUBSTITUTE USAGE PER INDICATION. 3

1.4 MACHINED BONE ALLOGRAFT MARKET.. 4

1.5 HYALURONIC ACID VISCOSUPPLEMENTATION MARKET . 5

1.6 RESORBABLE FIXATION DEVICE MARKET ... 6

1.7 TENDON GRAFT MARKET. 7

1.8 CARTILAGE REPAIR MARKET... 8

1.9 PLATELET AND BONE MARROW CONCENTRATION MARKET... 9

1.10 ORTHOPEDIC STEM CELL MARKET .. 10

1.11 LEADING COMPETITORS ... 11

RESEARCH METHODOLOGY... 12

2.1 RESEARCH SCOPE ... 12

2.2 IDATA'S 9-STEP METHODOLOGY ... 12

Step 1: Project Initiation & Team Selection .. 13

Step 2: Prepare Data Systems and Perform Secondary Research. 15

Step 3: Preparation for Interviews & Questionnaire Design 16

Step 4: Performing Primary Research... 17

Step 5: Research Analysis: Establishing Baseline Estimates 19

Step 6: Market Forecast and Analysis ... 20

Step 7: Identify Strategic Opportunities 22

Step 8: Final Review and Market Release . 23

Step 9: Customer Feedback and Market Monitoring. 24

 

U.S. ORTHOPEDIC BIOMATERIALS MARKET OVERVIEW. 25

3.1 INTRODUCTION ... 25

3.1.1 Growth Factors. 26

3.1.2 Bone Graft Substitutes .. 26

3.1.3 Machined Bone Allografts 27

3.1.4 Hyaluronic Acid Viscosupplementation 27

3.1.5 Resorbable Fixation Devices 28

3.1.6 Tendon Grafts ... 28

3.1.7 Cartilage Repair ... 28

3.1.8 Platelet and Bone Marrow Concentration 29

3.1.9 Orthopedic Stem Cell Therapy.. 29

3.2 MARKET ANALYSIS AND FORECAST .. 30

3.2.1 Market by Segment 30

3.2.2 Trend Analysis .. 37

3.3 MARKET DRIVERS AND LIMITERS .. 41

3.3.1 Market Drivers.. 41

3.3.2 Market Limiters. 42

3.4 COMPETITIVE ANALYSIS 44

3.4.1 Market Concentration... 49

3.5 MERGERS AND ACQUISITIONS 51

3.5.1.1 Osteotech Acquired Distributorship of Harvest Technologies System 51

3.5.1.2 Regeneration Technologies Merged with Tutogen Medical Inc. .51

3.5.1.3 NuVasive Acquired Osiris Therapeutics' Osteocel® Product..51

3.5.1.4 NuVasive Acquired Cervitech..51

3.5.1.5 Biomet Acquired Cartilix.51

3.5.1.6 Alphatec Holdings Acquired Scient'x Groupe.52

3.5.1.7 Anika Acquired Fidia Advanced Biopolymers.52

3.5.1.8 Baxter International Acquired ApaTech..52

3.5.1.9 Stryker Acquired Orthovita..52

3.5.1.10 Olympus Biotech Acquired OP-1TM from Stryker ..53

3.5.1.11 Histogenics Acquired ProChon Biotech 53

GROWTH FACTOR MARKET 54

4.1 INTRODUCTION ... 54

 

4.1.1 Overview... 54

4.1.2 BMP-2 (Medtronic)... 55

4.1.3 BMP-7 (Olympus Biomaterials) ... 55

4.1.4 Potential Complications ... 56

4.1.5 Reimbursement.. 57

4.1.6 Future Indications. 57

4.2 MARKET ANALYSIS AND FORECAST .. 59

4.3 MARKET DRIVERS AND LIMITERS .. 62

4.3.1 Market Drivers.. 62

4.3.2 Market Limiters. 63

4.4 COMPETITIVE ANALYSIS 66

4.4.1 Leading Competitors. 66

4.4.2 Potential Competitors ... 67

BONE GRAFT SUBSTITUTE MARKET 69

5.1 INTRODUCTION ... 69

5.2 MARKET SEGMENTATION... 70

5.2.1 Indications 70

5.2.1.1 Spine 70

5.2.1.2 Trauma.71

5.2.1.3 Extremities ...71

5.2.2 Materials... 71

5.2.2.1 Autografts 71

5.2.2.2 Standard Allografts..71

5.2.2.3 Demineralized Bone Matrix.71

5.2.2.4 Synthetics .72

5.2.2.5 Xenografts73

5.3 PROCEDURES... 74

5.3.1 Total Procedures... 74

5.3.2 Spinal Procedures. 75

5.4 UNITS PER PROCEDURE... 78

5.5 MARKET OVERVIEW... 80

5.5.1 Market by Material ... 80

5.5.2 Market by Indication. 84

5.6 MARKET ANALYSIS AND FORECAST .. 89

5.6.1.1 Spinal Bone Graft Substitute Market ...91

5.6.1.2 Cervical Spinal Bone Graft Substitute Market 93

5.6.1.3 Thoracolumbar Spinal Bone Graft Substitute Market .95

5.6.1.4 Trauma Bone Graft Substitute Market.97

5.6.1.5 Large Joint Reconstruction Bone Graft Substitute Market..99

5.6.1.6 Foot Reconstruction Bone Graft Substitute Market...101

5.6.1.7 Craniomaxillofacial Bone Graft Substitute Market...103

5.6.1.8 Oncology Bone Graft Substitute Market105

5.6.2 Bone Graft Substitute Market by Material.. 107

5.6.2.1 Allograft.107

5.6.2.1.1 Total Allograft Market 107

5.6.2.1.2 Spinal Allograft...111

5.6.2.1.2.1 Cervical Spinal Allograft. 111

5.6.2.1.2.2 Thoracolumbar Spinal Allograft 112

5.6.2.1.3 Trauma Allograft 113

5.6.2.1.3.1 Non-Union Fracture Allograft Market. 113

5.6.2.1.3.2 Fresh-Fracture Allograft Market ... 114

5.6.2.1.4 Joint Reconstruction Allograft115

5.6.2.1.4.1 Hip Reconstruction Allograft 115

5.6.2.1.4.2 Knee Reconstruction Allograft . 116

5.6.2.1.5 Foot Reconstruction Allograft 117

5.6.2.1.6 Craniomaxillofacial Allograft.117

5.6.2.1.7 Oncology Allograft .118

5.6.2.2 Demineralized Bone Matrices ...119

5.6.2.2.1 Total DBM Market..119

5.6.2.2.2 Spinal DBM 122

5.6.2.2.2.1 Cervical Spinal DBM... 122

5.6.2.2.2.2 Thoracolumbar Spinal DBM. 123

5.6.2.2.3 Trauma DBM..124

5.6.2.2.3.1 Non-Union DBM 124

5.6.2.2.3.2 Fresh-Fracture DBM... 125

5.6.2.2.4 Joint Reconstruction DBM..126

5.6.2.2.4.1 Hip Reconstruction DBM.. 126

 

5.6.2.2.4.2 Knee Reconstruction DBM... 127

5.6.2.2.5 Foot Reconstruction DBM ..128

5.6.2.2.6 Craniomaxillofacial DBM Market..128

5.6.2.2.7 Oncology DBM ...129

5.6.2.3 Synthetic Bone Graft Substitute Market.130

5.6.2.3.1 Total Synthetic Market130

5.6.2.3.2 Spinal Synthetic...133

5.6.2.3.2.1 Cervical Synthetic 133

5.6.2.3.2.2 Thoracolumbar Synthetic ... 134

5.6.2.3.3 Trauma Synthetic 135

5.6.2.3.3.1 Non-Union Fracture Synthetic.. 135

5.6.2.3.3.2 Fresh Fracture Synthetic. 136

5.6.2.3.4 Joint Reconstruction Synthetic137

5.6.2.3.4.1 Hip Reconstruction Synthetic 137

5.6.2.3.4.2 Knee Reconstruction Synthetic. 138

5.6.2.3.5 Foot Synthetic .139

5.6.2.3.6 Craniomaxillofacial Synthetic 139

5.6.2.3.7 Oncology Synthetic .140

5.7 MARKET DRIVERS AND LIMITERS 141

5.7.1 Market Drivers 141

5.7.1.1 Standard Allograft Market.141

5.7.1.2 DBM Market ..142

5.7.1.3 Synthetic Market 143

5.7.2 Market Limiters... 144

5.7.2.1 Standard Allograft Market.144

5.7.2.2 DBM Market ..145

5.7.2.3 Synthetic Market 145

5.8 COMPETITIVE ANALYSIS .. 147

5.8.1 Bone Graft Substitute Market . 147

5.8.1.1 Allograft Market 150

5.8.1.2 DBM Market ..152

5.8.1.3 Synthetic Bone Graft Substitute Market.154

ORTHOPEDIC STEM CELL MARKET... 157

6.1 INTRODUCTION . 157

6.2 MARKET OVERVIEW. 158

6.2.1 Lineage ... 158

6.2.1.1 Human Embryonic Stem Cells (hESC) ..158

6.2.1.2 Mesenchymal Stem Cells (MSC)158

6.2.2 Legislation .. 159

6.2.3 Other Therapeutic Applications.. 159

6.3 MARKET ANALYSIS AND FORECAST 160

6.3.1 Total Market ... 160

6.3.1.1 Lumbar Spine Stem Cell Market163

6.3.1.2 Cervical Spine Stem Cell Market...165

6.4 MARKET DRIVERS AND LIMITERS 167

6.4.1 Market Drivers 167

6.4.2 Market Limiters... 168

6.5 COMPETITIVE ANALYSIS .. 170

6.5.1 Leading Competitors... 170

6.5.2 Potential Competitors . 171

MACHINED BONE ALLOGRAFT MARKET. 174

7.1 INTRODUCTION . 174

7.1.1 Approaches . 175

7.1.1.1 Anterior Lumbar Interbody Fusion (ALIF) ...175

7.1.1.2 Posterior Lumbar Interbody Fusion (PLIF)..175

7.1.1.3 Transforaminal Lumbar Interbody Fusion (TLIF) 175

7.1.1.4 Extreme Lateral Interbody Fusion (XLIF).176

7.1.1.5 Cervical .176

7.2 PROCEDURES. 177

7.3 MARKET OVERVIEW. 180

7.4 MARKET FORECAST AND ANALYSIS 182

7.4.1 ALIF Approach ... 185

7.4.2 PLIF Approach ... 188

7.4.3 TLIF Approach ... 191

7.4.4 Cervical Machined Bone Allografts 194

 

7.5 MARKET DRIVERS AND LIMITERS 197

7.5.1 Market Drivers 197

7.5.2 Market Limiters... 198

7.6 COMPETITIVE ANALYSIS .. 200

PLATELET AND BONE MARROW ASPIRATE CONCENTRATION MARKET. 203

8.1 INTRODUCTION . 203

8.1.1 Platelet Rich Plasma... 204

8.1.2 Bone Marrow Aspirate 206

8.2 MARKET OVERVIEW. 207

8.3 MARKET ANALYSIS AND FORECAST 212

8.3.1 Total Platelet Concentration Market .. 215

8.3.1.1 Spinal Platelet Concentration Market ...218

8.3.1.2 Extremity and Sports Medicine Platelet Concentration Market220

8.3.2 Total Bone Marrow Aspirate Concentration Market.. 222

8.4 MARKET DRIVERS AND LIMITERS 224

8.4.1 Market Drivers 224

8.4.2 Market Limiters... 225

8.5 COMPETITIVE ANALYSIS .. 227

TENDON GRAFT MARKET.. 231

9.1 INTRODUCTION . 231

9.1.1 Repair Methods... 231

9.1.1.1 Bone-Patellar Tendon-Bone (BTB) Graft, ACL/PCL Surgery ..231

9.1.1.2 Soft Tissue Grafts...231

9.1.1.3 Allograft Tendons ..232

9.1.1.4 Ligament and Tendon Synthetic Grafts .232

9.2 PROCEDURES. 234

9.3 MARKET FORECAST AND ANALYSIS 235

9.4 MARKET DRIVERS AND LIMITERS 237

9.4.1 Market Drivers 237

9.4.2 Market Limiters... 238

9.5 COMPETITIVE ANALYSIS .. 239

CARTILAGE REPAIR MARKET.. 242

10.1 INTRODUCTION ... 242

10.1.1 Methods for Cartilage Repair... 242

10.2 PROCEDURES... 244

10.3 MARKET ANALYSIS AND FORECAST .. 245

10.3.1 Cartilage Repair Market... 245

10.3.2 Autologous Chondrocyte Implantation Market. 247

10.3.3 Osteochondral Allograft Market... 249

10.3.4 Meniscal Graft Market.. 251

10.4 MARKET DRIVERS AND LIMITERS .. 253

10.4.1 Market Drivers.. 253

10.4.2 Market Limiters. 253

10.5 COMPETITIVE ANALYSIS 255

10.5.1 Leading Competitors. 255

10.5.2 Emerging Competitors.. 256

HYALURONIC ACID VISCOSUPPLEMENTATION MARKET . 259

11.1 INTRODUCTION ... 259

11.1.1 Benefits of Viscosupplementation . 260

11.1.2 Synovial Fluid ... 260

11.1.3 Product Types ... 261

11.1.3.1 Single-Injection Products 261

11.1.3.2 Three-Injection Cycle Products ...261

11.1.3.3 Three/Five-Injection Cycle Products...262

11.1.4 Reimbursement.. 262

11.2 MARKET OVERVIEW... 263

11.3 MARKET ANALYSIS AND FORECAST .. 268

11.3.1 Total Market . 268

11.3.1.1 Single-Injection Hyaluronic Acid Viscosupplementation Market271

11.3.1.2 Three-Injection Cycle Hyaluronic Acid Viscosupplementation Market ..274

11.3.1.3 Five-Injection Cycle Hyaluronic Acid Viscosupplementation Market 277

11.4 MARKET DRIVERS AND LIMITERS .. 280

11.4.1 Market Drivers.. 280

11.4.2 Market Limiters. 281

 

, 2012 www.idataresearch.net ix

11.5 COMPETITIVE ANALYSIS 283

RESORBABLE FIXATION MARKET.. 287

12.1 INTRODUCTION ... 287

12.1.1 Materials... 287

12.1.2 Disadvantages Compared to Metal Fixation 288

12.1.3 Indications and Product Descriptions .. 288

12.1.3.1 Shoulder Fixation 288

12.1.3.2 Knee Reconstruction289

12.2 MARKET OVERVIEW... 291

12.3 MARKET ANALYSIS AND FORECAST .. 295

12.3.1 Resorbable Fixation Market . 295

12.3.2 ACL/PCL Resorbable Fixation Market 297

12.3.2.1 Femoral Fixation .297

12.3.2.2 Tibia Fixation Market..301

12.3.3 Meniscal Resorbable Fixation Market.. 304

12.3.4 Rotator Cuff Resorbable Fixation Market 308

12.3.5 Labrum Repair Market . 311

12.4 MARKET DRIVERS AND LIMITERS .. 314

12.4.1 Market Drivers.. 314

12.4.1.1 Shoulder Fixation 314

12.4.1.2 Knee Fixation...314

12.4.2 Market Limiters. 315

12.4.2.1 Shoulder Fixation 315

12.4.2.2 Knee Fixation...316

12.5 COMPETITIVE ANALYSIS 318

12.5.1 Leading Competitors. 318

12.5.2 Other Notable Competitors... 319

ABBREVIATIONS 322

 

To order this report: Biomaterial Industry: U.S. Market for Orthopedic Biomaterials 2012

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