Navigation Links
Two Large, Independent Outcomes Trials Offer New Important Safety Information on Cardiovascular Effects of AVANDIA(R)
Date:6/9/2008

SAN FRANCISCO, June 9 /PRNewswire/ -- Two long-term, large-scale and independent studies evaluating cardiovascular (CV) outcomes in people with type 2 diabetes enrolled more than 9,300 patients taking AVANDIA(R) (rosiglitazone maleate) and provide more than 20,000 patient years of additional experience with AVANDIA. The Veterans Affairs Diabetes Trial (VADT), through two separate analyses, concluded that based on results from VADT, there is no evidence to suggest that use of AVANDIA increases the risk for CV mortality and morbidity in patients with type 2 diabetes. A second trial, The Action to Control Cardiovascular Risk in Diabetes (ACCORD), found that AVANDIA was not associated with any increased risk of death. These findings display a safety profile consistent with results from other long-term studies with AVANDIA. These studies were presented during the 68th Scientific Sessions of the American Diabetes Association (ADA) in San Francisco, CA.

"The findings on AVANDIA should be reassuring to physicians who prescribe AVANDIA and patients who use AVANDIA for their type 2 diabetes," added R. Paul Aftring, MD, PhD, AVANDIA Clinical Lead at GlaxoSmithKline. "The safety findings on AVANDIA from these two trials add substantial patient experience to the large body of existing evidence on the safety profile of the medication."

Findings from VADT

VADT evaluated whether intense blood sugar control in patients with type 2 diabetes would reduce major CV events. The study continued for 7.5 years. In total, 1,704 patients enrolled in VADT took AVANDIA.

The primary result of VADT did not show that intensive blood sugar control (HbA1c levels below 7%) had a statistically significant effect on reducing major CV events associated with diabetes. However, there was a favorable trend in reducing all CV events, except CV death and inoperable heart disease, among the patients in the intensive arm. There were significantly fewer CV events in the trial
'/>"/>

SOURCE GlaxoSmithKline
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Large, Long-Term Veterans Affairs Diabetes Trial (VADT) Reveals Important Cardiovascular Safety News on AVANDIA(R)
2. MultiVu Video Feed: Large, Long-Term Veterans Affairs Diabetes Trial (VADT) Reveals Important Cardiovascular Safety News on AVANDIA
3. Video: New Research Discovers Independent Brain Networks Control Human Walking
4. Facet Solutions AFRS(TM) Demonstrates Biomechanical Advantages Over Dynamic Stabilization in Independent Testing
5. Independent Clinical Results Confirm Up to a 7-Centimeter Reduction in Body Circumference Using UltraShape(TM) Non-Invasive Fat Reduction and Body Contouring System
6. Independent Physician Surveys Show if Approved, MF101 Could Become First-Line Treatment for Menopause Symptoms
7. Independent Data Safety Monitoring Board Recommends Continuation of Sangarts Pivotal Phase III Trials of Hemospan(R) Following Second Interim Review
8. Longevinex(R) Found to be Superior to Green Tea Molecule in Independent Human Study
9. Independent Studies Report on Possible Roles for Cylexs Immune Cell Function Assay in Monitoring of Heart and Lung Transplant Recipients
10. Seven Presentations by Two Independent Research Groups Highlight Advantages of Pressure Cycling Technology (PCT) at Scientific Symposia in Philadelphia, Boston, and New York City
11. Video: Major Independent Trial Demonstrates Significant Anticancer Benefit of Zometa(R) in Women With Early-Stage Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/27/2015)...  Organovo Holdings, Inc. (NYSE MKT: ONVO) ("Organovo"), ... 3D bioprinting technology, announced today that Keith ... present live at VirtualInvestorConferences.com on March 5th. ... for this Company update," said Mr. Murphy. "We ... of the exVive3D Liver, Bioprinted Human Tissue, commercialization ...
(Date:2/27/2015)... YORK , Feb. 27, 2015 /PRNewswire/ ... are increasing in applications as their effectiveness ... firm Kalorama Information.  Kalorama Information says that ... is the most powerful tool in proteomic ... spec; MS) through its traditional techniques has ...
(Date:2/26/2015)... , Feb. 26, 2015  Today the National ... The psychological and physical side effects of pain medications ... painkillers, such as Vicodin and Oxycontin, are safer options ... overdose on prescription painkillers than on heroin and cocaine ... CEO of NSC. "Yet, these medications are marketed as ...
Breaking Medicine Technology:Organovo Holdings, Inc. to Provide Corporate Update and Investor Presentation in a Live, Interactive Webcast on March 5th 2Organovo Holdings, Inc. to Provide Corporate Update and Investor Presentation in a Live, Interactive Webcast on March 5th 3Organovo Holdings, Inc. to Provide Corporate Update and Investor Presentation in a Live, Interactive Webcast on March 5th 4Report: "Softer" Mass Spec Techniques Gaining Popularity in Biomarker Discovery 2Report: "Softer" Mass Spec Techniques Gaining Popularity in Biomarker Discovery 3National Safety Council: Opioid prescription painkillers have hidden, deadly side effects 2
... Eli Lilly and Company (NYSE: LLY ) will announce its ... 2010 .  Lilly will also conduct a conference call on that day with ... , , , ... from 9:00 a.m. to 10:00 a.m. EDT .  Investors, media and the ...
... RALEIGH, N.C. , July 9 Pioneer Surgical Technology, ... technical biologic expertise to support their growing line of products that address ... , , ... stated, "We are extremely pleased with our ability to provide innovative biologic ...
Cached Medicine Technology:Lilly Confirms Date and Conference Call for Second-Quarter 2010 Financial Results Announcement 2Pioneer® Surgical Expands Product Specialists to Support Growing Biologics Business 2
(Date:2/28/2015)... 2015 The Mesothelioma Applied Research ... at the International Symposium on Malignant Mesothelioma on Monday, ... the Hyatt Regency Bethesda in Bethesda, Maryland. The following ... and commitment to the mission to cure mesothelioma. , ... be presented to Miriam Ratner. Miriam runs the Meso ...
(Date:2/28/2015)... Beach, CA (PRWEB) February 28, 2015 ... needs of Central Coast area residents, recently announced a ... System. It’s a treatment option for new and ... kick off 2015 with a bright, white smile, Dr. ... discounted price of $299, marked down from the regular ...
(Date:2/28/2015)... Kaylie Corrigan, Outdoor Supervisor at Back2Basics ... current student obtaining her Masters degree in social work ... in psychoeducation on substance use for teens at the ... of her studies. , “Even though these students are ... at the high school and junior high school level,” ...
(Date:2/28/2015)... February 28, 2015 The noted Friedman ... that they have officially relaunched their website. The new ... but it contains a new section about their team ... read the full biographies of each Friedman Dental Group ... the website was designed to provide our patients with ...
(Date:2/28/2015)... Janesville, WI (PRWEB) February 28, 2015 ... The designation recognizes Mercy Harvard Hospital as stroke capable ... to be brought via ambulance to Mercy Harvard Hospital. ... the state to indicate their ability to treat stroke ... The designation allows ambulances transporting stroke patients to bypass ...
Breaking Medicine News(10 mins):Health News:Cancer Research Foundation Honors Award Recipients 2Health News:Cancer Research Foundation Honors Award Recipients 3Health News:Cancer Research Foundation Honors Award Recipients 4Health News:Pismo Beach Dentist Announces Special for Zoom! Teeth Whitening 2Health News:Staff at Arizona Drug Addiction Treatment Center Starts Teen Sobriety Support Group at Local High School 2Health News:Friedman Dental Group Announces Their Updated Website 2Health News:Mercy Harvard Hospital Recognized as Leader in Stroke Care - Javon Bea 2
... of East Anglia,s Climatic Research Unit (CRU) are leaked on the ... calls for a debate into science and transparency. , Emails were ... ,Information Gap, leading science writer Fred Pearce argues that ,if CRU ... great deal of time and angst on the part of its ...
... Cambridge, Mass. November 30, 2011 From targeted ... the 21st century may prove to be the age ... though, will be miniscule. Experts in chemistry, applied ... week for the BASF Advanced Research Initiative at Harvard ...
... creatures on Earth have skin that produces the greatest ... becoming new weapons in the battle against antibiotic-resistant infections, ... (like rotten fish, for instance) that scientists term them ... Research . Yun Zhang, Wen-Hui Lee and Xinwang ...
... -- There may be a link between high blood sugar ... women, a new study finds. Researchers analyzed 12 years ... Women,s Health Initiative study. The women,s fasting blood sugar (glucose) ... study and then several more times over the next dozen ...
... have a financial interest in imaging equipment are more ... exams, according to a study presented today at the ... (RSNA). "Self-referral," whereby a non-radiologist physician orders ... which that physician has a financial interest, is a ...
... HealthDay Reporter , TUESDAY, Nov. 29 (HealthDay News) ... In a 12-month study of 123 overweight or obese women, ... than those who skipped a mid-morning nosh. The finding ... the short interval between breakfast and lunch for these snackers, ...
Cached Medicine News:Health News:Is transparency bad for science? 2Health News:Nano meets pharma at Harvard-BASF symposium 2Health News:Nano meets pharma at Harvard-BASF symposium 3Health News:Women's High Blood Sugar Linked to Colorectal Cancer: Study 2Health News:Self-referral leads to more negative exams for patients 2Health News:Mid-Morning Snacks May Thwart Diets 2Health News:Mid-Morning Snacks May Thwart Diets 3
... Deluxe specimen bath mounts inside the existing black ... for the separation of buffer and ice kept ... can be sterilized and has round mounting disks ... The disks and bath surface are marked ...
Punch set for Advanced Tissue Arrayer, 1.5 mm...
Inquire...
Inquire...
Medicine Products: