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Twelve DOXIL(R) Clinical Studies to be Presented at American Society of Hematology Annual Meeting
Date:12/7/2007

thasone in the Treatment of Previously Untreated Multiple

Myeloma Patients: Impact on Quality-of-Life - Andrew Belch, Cross

Cancer Institute, Edmonton, Alberta, Canada (Abstract 3618)

-- Monday, December 10, 2007, 5:00 p.m.-7:00 p.m., Hall B3 and B4

(Poster Board #:837-III)

-- Pegylated Liposomal Doxorubicin (PLD), Dexamethasone and Low Dose

Thalidomide (DDt): An Active Regimen in the Frontline Therapy for

Multiple Myeloma (MM) - Delva Deauna-Limayo, University of Kansas

Medical Center, Kansas City, KS (Abstract 3619)

-- Monday, December 10, 2007, 5:00 p.m.-7:00 p.m., Hall B3 and B4

(Poster Board #:838-III)

-- Preliminary Results of a Phase II Study of HCVID DOXIL Alternated with

Methotrexate-Cytarabine in Patients with Newly Diagnosed T-Cell

Lymphoma - Barbara Pro, M.D. Anderson Cancer Center, Houston, TX

(Abstract 3456)

-- Monday, December 10, 2007, 5:00 p.m.-7:00 p.m., Hall B3 and B4

(Poster Board #: 675-III)

-- Phase II study of RCHOP with Pegylated Liposomal Doxorubicin (DRCOP)

for Patients > 60 Years Old with Untreated Diffuse Large B Cell

Lymphoma (DLBCL) - Maria Alma Rodriguez, University of Texas M.D.

Anderson Cancer Center, Houston, TX (Abstract 4468 [accepted as

abstract only])

About DOXIL

DOXIL in combination with VELCADE(R) (bortezomib) for Injection is indicated for the treatment of patients with multiple myeloma who have not previously received VELCADE and have received at least one prior therapy.

IMPORTANT SAFETY INFORMATION

BOXED WARNINGS

Cardiotoxicity, infusion reaction, myelosuppression, liver impairment, Substitution
-- The use of DOXIL may lead to cardiac toxicity. Myocardial damage may

lead to congestive heart failure and may occur as the total cumulative

dose of doxorubicin HCl approach
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SOURCE Ortho Biotech
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