Navigation Links
Tumor Eradication Article Published by Cancer Research
Date:11/12/2007

Preclinical results make compelling case for clinical testing in human

cancer patients

SAN DIEGO, Nov. 12 /PRNewswire/ -- In its Oct. 15 issue, Cancer Research published a peer-reviewed article from Genelux Corporation describing successful eradication of human breast cancer tumors in animals using GL-ONC1, a novel oncolytic virus developed by Genelux scientists. These promising results make a compelling case for the use of GL-ONC1 in human cancer patients. Clinical trials are scheduled to begin in the near future.

"We believe this research represents a significant advance in tumor therapy and diagnosis," said President and CEO Aladar A. Szalay, PhD, an internationally-recognized scientist who founded Genelux Corporation in 2001.

The article, titled "Eradication of Solid Human Tumors in Nude Mice with an Intravenously Injected Light-Emitting Oncolytic Vaccinia Virus," documents animal studies that have resulted in complete eradication of human breast tumors without any observed toxicity using a single intravenous injection of GL-ONC1. In the studies, GL-ONC1 located and replicated selectively within tumors, leading to successful tumor destruction. Scientists were able to monitor tumor regression and elimination in real time using a light-emitting fusion protein encoded in the virus.

GL-ONC1 also stimulated the body's own natural defenses to fight the cancer. After administration, tumor-specific viral colonization enables the immune system to recognize tumors as foreign elements and activate defense mechanisms to fight them. These increased innate and adaptive immune responses further contribute to the regression and eventual eradication of the tumor.

This research was conducted in collaboration with scientists at the National Institutes of Health, Department of Transfusion Medicine and Center for Information Technology, in Bethesda, Maryland; and the Virchow Center for Experimental Biomedicine at t
'/>"/>

SOURCE Genelux Corporation
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. HistoRx and Radiation Therapy Oncology Group Initiate Brain Tumor Biomarker Research Partnership
2. Peregrine Reports Data Showing Bavituximabs Potential to Shrink Prostate Tumors
3. Peregrine Researchers Report Data Showing Bavituximabs Potential to Shrink Human Prostate Tumors in Model of Relapsed Disease
4. Vion Pharmaceuticals Announces Initiation of a Phase I/II Trial of Cloretazine(R) (VNP40101M) in Combination with Temodar(R) in Adult Brain Tumors
5. Proteolix Initiates Multicenter Open-label Study of the Safety and Activity of Carfilzomib in Subjects With Relapsed Solid Tumors
6. Pharmion and MethylGene Initiate Phase One Combination Clinical Trial with MGCD0103 and Taxotere(R) in Patients with Solid Tumors
7. Tumor Growth Inhibition and Pharmacokinetic Profile of NKTR-102 (PEG-Irinotecan) in Multiple Solid Tumors To Be Presented at Upcoming AACR-NCI-EORTC International Conference
8. Roche Announces Positive Results in Solid Tumors Using Human Monoclonal Antibody Against IGF-1R (R1507)
9. Updated Phase 1 Data for Exelixis XL184 Demonstrate Pharmacodynamic and Clinical Anti-Tumor Activity
10. Kosan Presents Phase 1 Data Showing Antitumor Activity and Safety Profile of Epothilone KOS-1584 at AACR/NCI/EORTC Meeting
11. Jennerex Presents Clinical Data From JX-594 Demonstrating Tumor Efficacy Against Advanced Liver Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... , Jan. 23, 2015  Today the U.S. Food and ... for the prevention of serogroup B meningococcal disease ... Pfizer,s vaccine Trumenba®, which received FDA approval in October, ... devastating disease. "I have heard over ...
(Date:1/23/2015)... Research and Markets ( http://www.researchandmarkets.com/research/5dh22x/urinary_catheters ) has ... (Indwelling or Foley Catheters, Intermittent Catheters and Male External ... Growth, Trends and Forecast 2014 - 2020" report ... the global market for urinary catheters is experiencing a ...
(Date:1/23/2015)... , Jan. 23, 2015  Northwest Biotherapeutics, Inc. (NASDAQ: ... immune therapies for operable and inoperable solid tumor cancers, announced ... the 7 th Annual Phacilitate Immunotherapy Forum in ... at Phacilitate will take place on January 26 at 10:30 ...
Breaking Medicine Technology:The National Meningitis Association (NMA) Applauds FDA Approval of Second Vaccine To Protect Against Serogroup B Meningococcal Disease 2Urinary Catheters Market (Indwelling or Foley Catheters, Intermittent Catheters and Male External or Condom Catheters) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Urinary Catheters Market (Indwelling or Foley Catheters, Intermittent Catheters and Male External or Condom Catheters) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 2NW Bio To Present At The 7th Annual Phacilitate Immunotherapy Forum 3
(Date:1/22/2015)... 2015 The federal court overseeing thousands of ... Court, Southern District of West Virginia has upheld a $2 ... first bellwether trial. In an Order dated January 21st, the ... finding that C.R. Bard had not proven a miscarriage of ...
(Date:1/22/2015)... January 22, 2015 Autocarinsurancebest.com has released a ... a commercial auto insurance policy . , Auto insurance ... vehicles. It is no longer necessary to call an agent ... now available online on a single website: http://autocarinsurancebest.com/ . ...
(Date:1/22/2015)... NY (PRWEB) January 22, 2015 ... of Sports Medicine flagship journal Medicine & Science ... L-Citrulline before exercise may help reduce gastrointestinal (GI) ... 1 , Participants in the double-blind, placebo-controlled ...
(Date:1/22/2015)... Colorado (PRWEB) January 22, 2015 Four years since ... Queen – which coincided with the marriage of Avasa & Matthew ... THE ROAD, which is scheduled for release through White Swan Records ... message that there is a sacred path available to all of ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 JJsHouse.com is a ... dresses. Today, the business announces its latest collection of ... , “The most important issue is the wedding dress on ... thing in a woman’s life. Every bride wants to find ...
Breaking Medicine News(10 mins):Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2
... SEATTLE Scientists at Fred Hutchinson Cancer Research Center have ... more widely-used method for treating leukemia and other blood cancers. ... Nature Medicine , Colleen Delaney, M.D., and colleagues describe ... number of stem/progenitor cells from a unit of cord blood ...
... usually runs out for those who don,t understand risk , ... and you,ll get better and win, right? , Wrong, says ... especially beginners -- win less money the more hands they ... 27 million online poker hands, suggest that small stakes translate ...
... The ... natural lip balm based on the timeless healing principles of ayurvedic medicine , ... Carlsbad, CA (PRWEB) January 17, 2010 -- ... and smooth this winter season. Adara Lip Balm heals dry, chapped lips with a signature ...
... Keep the World Focused on Haiti , NEW YORK ... the joint efforts of President Obama and Former Presidents Bill Clinton ... the crisis in Haiti is sustained over the long-term. , ... President Obama and Former Presidents Bill Clinton and George W. ...
... ... of their new online store, featuring free shipping and the guaranteed lowest price on fitness ... Phoenix, AZ (PRWEB) ... pleased to announce the launch of their new online store, featuring free shipping and the ...
... one-third, study finds , SATURDAY, Jan. 16 (HealthDay News) ... with hay fever by one-third and drug prescription costs ... , Researchers compared the medical claims for 2,770 ... vaccinations with the claims of 11,000 children with allergic ...
Cached Medicine News:Health News:First successful use of expanded umbilical-cord blood units to treat leukemia 2Health News:First successful use of expanded umbilical-cord blood units to treat leukemia 3Health News:Novice Poker Players Don't Know When to Walk Away 2Health News:Pamper and Soothe Your Lips with the Chopra Center's New Adara Certified Organic Lip Balm 2Health News:President Obama Tasks Former Presidents Bush and Clinton with Fundraising for Haiti Recovery 2Health News:President Obama Tasks Former Presidents Bush and Clinton with Fundraising for Haiti Recovery 3Health News:Fitness4HomeOnline.com Features Fitness Equipment Online with Free Shipping and Guaranteed Lowest Price 2Health News:Shots Relieve Children's Hay Fever, Cut Expenses 2
... new Propaq LT is the perfect monitor ... basic parameters of continuous vital signs monitors ... making it perfect for just about any ... Light enough to clip on an IV ...
Exxcel Soft ePTFE vascular graft, designed for exceptional kink resistance and crush resistance, maintains a Soft touch for easier handling during peripheral vascular bypass procedures and vascular a...
... is used for the processing ... independent medical billers. It is ... generate and transmit claims to ... commercial insurance carriers. It utilizes ...
BillingPro...
Medicine Products: