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Trubion Pharmaceuticals Announces Presentation of Positive Data From Phase IIb and Re-treatment Studies With TRU-015 in Patients With Rheumatoid Arthritis
Date:11/8/2007

SEATTLE, Nov. 8 /PRNewswire-FirstCall/ -- Trubion Pharmaceuticals Inc. (Nasdaq: TRBN) today announced presentation of positive data from a Phase IIb study that showed that Trubion's TRU-015 for rheumatoid arthritis (RA) provided statistically significant efficacy after a single infusion of 800 mg or 1,600 mg. In addition, Trubion also announced presentation of data showing that repeat administration with TRU-015 was well tolerated and resulted in a consistent pharmacokinetic (PK) and pharmacodynamic (PD) profile. Trubion is co-developing TRU-015 with Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), for the treatment of rheumatoid arthritis.

These data will be presented during two poster sessions at the annual meeting of the American College of Rheumatology (ACR) on Nov. 8 and 9, 2007. The posters are available in the Events section of Trubion's Web site at http://investors.trubion.com/events.cfm.

"TRU-015's ability to significantly improve RA signs and symptoms following a single infusion could represent a new level of convenience for patients and physicians. These results also suggest that clinical responses may be maintained during B-cell recovery," said Peter Thompson, M.D., FACP, president, chief executive officer and chairman of Trubion. "We and our partner have agreed on a design for our next study that we believe could be supportive of a registration package, and we look forward to TRU
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SOURCE Trubion Pharmaceuticals Inc.
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