Navigation Links
Trubion Initiates Phase 1/2 Study of TRU-016 in CLL, Announces Next-Generation Product Candidate for RA and Provides Product Pipeline Update
Date:3/27/2008

rward to the results of TRU-016's ongoing clinical evaluation," said Peter Thompson, M.D., FACP, president, CEO and chairman of Trubion. "Our proprietary product candidate, TRU-016, has demonstrated potent anti-tumor activity in pre-clinical evaluation and may provide patients with improved therapeutic options or benefits when used alone or in conjunction with chemotherapy or CD20-targeted immunopharmaceuticals."

SBI-087 for RA

Trubion also announced today that its collaboration partner Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), has filed an investigational new drug (IND) application for SBI-087 for rheumatoid arthritis (RA), and clinical trial sites are preparing to enroll patients in a Phase 1 study. In collaboration with Trubion, Wyeth Pharmaceuticals is developing SBI-087 and other CD20-directed products. SBI-087 for RA builds on Trubion and Wyeth's clinical experience with Trubion's lead compound, TRU-015, and is based on Trubion's Small Modular ImmunoPharmaceutical (SMIP(TM)) technology.

With SBI-087, Trubion's pipeline now includes two differentiated compounds under development for the treatment of autoimmune and inflammatory diseases. Trubion and Wyeth are leveraging Trubion's SMIP(TM) technology to create a portfolio of product candidates with customized mechanisms of action in an effort to optimize patient safety, efficacy and convenience.

The Phase 1 SBI-087 dose escalation clinical trial is designed to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of a single dose of SBI-087 in patients with RA. Pre-clinical research suggests that SBI- 087, a fully humanized CD20-directed SMIP, has enhanced potency in B-cell depletion in vivo compared to Rituxan and other CD20-directe
'/>"/>

SOURCE Trubion Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. Trubion Announces Initiation of Phase I/II Clinical Trial of TRU-015 for the Treatment of B-Cell Non-Hodgkins Lymphoma
2. Trubion Pharmaceuticals Announces Presentation of Positive Data From Phase IIb and Re-treatment Studies With TRU-015 in Patients With Rheumatoid Arthritis
3. Trubion Announces Preliminary Analysis of Phase IIb Results With TRU-015 in Rheumatoid Arthritis
4. Repligen Initiates Phase 3 Clinical Trial of RG1068 for Pancreatic MRI Imaging
5. Metabolex Initiates Phase 1 Trial of MBX-2982
6. Phosphagenics Initiates its Phase 2 Clinical Trial in Type 1 Diabetes
7. Nventa Enrolls and Initiates Dosing of Final Cohort in HspE7 Phase 1 Cervical Dysplasia Trial
8. Ception Therapeutics Initiates Phase II/III Clinical Trial for Its Lead Product Reslizumab in Eosinophilic Esophagitis (EE) in Children
9. Pharmacopeia Initiates Second Phase 2 Hypertension Study with PS433540 (DARA)
10. Phosphagenics Initiates U.S. Clinical Trials for Its Topical Retinoic Acid
11. Alexza Initiates AZ-007 (Staccato(R) Zaleplon) Phase 1 Clinical Trial and Updates Clinical Pipeline Development Status
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/17/2013)... Fla. , May 17, 2013 Fuse Science, ... delivery technology company that is developing new, patent-pending technologies poised ... announced today that it will hold a business update teleconference ... May 22 nd , 2013 at 4:30 PM ET. ... will host the call and will be joined ...
(Date:5/17/2013)... , May 17, 2013 Oramed ... of oral drug delivery systems, announced today that the ... the Company,s Investigational New Drug application(IND) for ORMD-0801, its ... to have the FDA clearance to proceed," stated ... upcoming trial is a major milestone for Oramed and ...
(Date:5/16/2013)... N.J. , May 16, 2013  PTC Therapeutics, ... statement on Form S-1 with the U.S. Securities and ... offering of its common stock. The number of shares ... offering have not been determined. (Logo:  ... Suisse are acting as joint book-running managers for the ...
Breaking Medicine Technology:Fuse Science, Inc. to Hold Business Update Webcast and Teleconference on May 22nd 2Oramed Receives FDA Clearance to Initiate Oral Insulin Trials in the U.S. 2Oramed Receives FDA Clearance to Initiate Oral Insulin Trials in the U.S. 3PTC Therapeutics, Inc. Files Registration Statement for Proposed Initial Public Offering 2
(Date:5/19/2013)... 6Webs.com is the leader in reviews ... are considering an alarm system can do a comparison ... security system providers online at 6Webs.com. Just recently finishing ... home security system companies, 6Webs.com currently is announcing ... home security companies before ranking the home security system ...
(Date:5/19/2013)... 19, 2013 Americans live closer to ... newest American Veterinary Medical Association (AVMA) U.S. Pet Ownership ... owners consider their dog a member of the family, ... as much five years earlier. , According to the ... the national income dedicated to pets has increased every ...
(Date:5/19/2013)... Los Angeles (PRWEB) May 19, 2013 Yeast ... infections can appear in sensitive areas of the human body. ... by Yeastrol. This new formula provides a unique method of ... This new spray solution is now provided to men and ... Yeast is naturally absorbed in the body through food and ...
(Date:5/19/2013)... Buenos Aires, Argentina: Yoga classes ( clases de Yoga ... by the Sivananda Yoga Vedanta Center. The center ... Norte). Classes are 90 minutes and are offered all ... a calm environment, allowing visitors to enjoy the benefits ... among others. , The Yoga classes follow the following ...
(Date:5/19/2013)... 2013 The Da Vinci robot lawyers ... in the nation’s first trial involving a Da Vinci ... State Superior Court, was filed by the widow of ... complications in a robot-assisted prostate removal, according to a ... robotic surgery lawsuit alleges those complication’s hastened his ...
Breaking Medicine News(10 mins):Health News:Top Rated DIY Home Security System Companies Published by 6Webs.com 2Health News:Dogs Becoming Part of the Family: Dog Bite Injuries Decreasing 2Health News:Dogs Becoming Part of the Family: Dog Bite Injuries Decreasing 3Health News:A Safe & Homeopathic Yeast Infection Relief by Yeastrol Now Available at HealthCareSupplementz.com with Massive Discount 2Health News:Clases de Yoga in Buenos Aires, Argentina (Yoga Classes) Now Offered by Sivananda Yoga Vedanta Center 2Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 2Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 3Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 4
... to experience 25% less muscle and joint pain in their ... study has also revealed that people who regularly participate in ... than non-runners even though they are more likely to suffer ... of the level of pain in a group of runners ...
... belief new studies point in the direction that a dose ... ,"High levels of daily stress are linked to a ... study carried out at the National Institute of Public Health, ... 18 years and asked about their routine levels of stress ...
... Compared to bare metal stents, placement of stents ... of the artery re-narrowing nine months following angioplasty ... to an article in the September 14 issue ... treatment of atherosclerotic coronary artery disease, according to ...
... on findings of a recent study researchers say that certain ... used to help current and former smokers ward off development ... worldwide. ,Researchers say their study provides significant insight ... by which the process can be slowed down after exposure ...
... early detection of breast cancer and the health officials recommend ... of the breasts for lumps every month for early diagnosis ... to start an early treatment which will give better treatment. ... England Journal of Medicine has shown that the newly developed ...
... has shown that there are few clinical comparisons available ... seeking the best individual drug for their children with ... to help make that choice. ,There are few ... relatively large variety of drugs prescribed for ADHD and ...
Cached Medicine News:Health News:Stents That Release Medication To Check Artery Narrowing 2Health News:Digital Mammogram For Detection Of Breast Cancer In Women With Dense Breasts 2Health News:Clinical Comparisons Between ADHD Drugs Are Less 2
... provider of Telemedicine monitoring and diagnostic ... service commitment to patients and prescribing ... testing devices that provide enhanced diagnostic ... standard telephone lines. TransMedEx's product line ...
... Raytel Cardiac Services is a ... uniquely qualified people, combined with state-of-the-art ... clinical information that supports healthcare professionals ... Cardiac Services uses telecommunications and ECG ...
... has developed a new, integrated technology ... heartbeat-by-heartbeat, ECG monitoring, analysis and response, ... service is initially focused on helping ... arrhythmia. Time is of the essence ...
... microplate incubator is an extremely compact ... single microplate up to 50C. ... requiring higher temperatures up to 65C. ... low cost and high performance for ...
Medicine Products: