Navigation Links
Trovagene, Inc., Announces Issuance of U.S. Patent for NPM Mutants to Diagnose and Monitor Acute Myeloid Leukemia
Date:7/18/2012

SAN DIEGO, July 18, 2012 /PRNewswire/ -- Trovagene, Inc. (Nasdaq:  TROV), a developer of transrenal molecular diagnostics, received notice of U.S. Patent 8,222,370, titled "Nucleophosmin protein (NPM) mutants, corresponding gene sequences and uses thereof."  This is the first U.S. patent issued around this mutation, and is part of a family of filed patents for Trovagene around NPM. Mutation analysis of nucleophosmin-1 (NPM1) is currently used for the diagnosis, stratification and monitoring of patients with acute myeloid leukemia (AML). 

(Logo: http://photos.prnewswire.com/prnh/20120620/LA28014LOGO)

AML is a clinically heterogeneous disease with about 200,000 new cases per year worldwide. Subgrouping of AML patients using karyotypic abnormalities provides for more individualized patient prognosis. However, in almost half of AML cases the karyotype appears normal and provides no guidance for the physician. A discovery by Drs. Falini and Mecucci, at the Institute of Hematology at the University of Perugia in Italy, showed that many AML patients have mutations in the NPM1 gene, and these mutations are a marker for more favorable clinical outcomes.

The National Comprehensive Cancer Network (www.nccn.org), which sets clinical standards for cancer treatment, has included testing for NPM mutations in their clinical practice guidelines (NCCN Guidelines™ Version 2.2011 – Acute Myeloid Leukemia). NPM1 mutation analysis helps physicians to select more appropriate treatment strategies for AML patients. NPM1 testing may also be useful for monitoring the effectiveness of treatment, minimal residual disease monitoring and detecting relapse, and stratifying AML patients when enrolling in clinical trials.

Trovagene holds an exclusive worldwide license to the patent.  To date, the Company has granted nonexclusiv
'/>"/>

SOURCE Trovagene, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Keith McCormick Joins Trovagene, Inc. as Head of Commercial Operations
2. A New Audio Interview With Ronald Adams President Of Medical Alarm Concepts Holding, Inc., Is Now At SmallCapVoice.com
3. Aperture Health, Inc., Targeting the Strong Growth in the Long Term Disease Management arena
4. Precision Optics Corporation Announces $1 Million Order for Microprecision™ Based Endoscopes
5. Young Innovations, Inc. Announces Record Sales and EPS for the Quarter Ended March 31, 2012
6. JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies
7. Misonix Announces New Distribution Agreement For Panama
8. University of Maryland BioPark Announces MedImmunes Dr. Bahija Jallal as Newest Member of Board of Directors for UM Health Sciences Research Park
9. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
10. Boston Scientific Announces CE Mark and European Launch of Emerge™ PTCA Dilatation Catheter
11. Soligenix Announces Further Progress with ThermoVax™ for Long-Term Vaccine ThermoStability
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... October 22, 2014 A new ... Market (Product type, Form, End user, Application and Geography) ... Analysis, Research, Report, Opportunities, Segmentation and Forecast, 2013 - ... market. Based on key trends tracked, it is anticipated ... $7.9 billion by 2020, registering a CAGR of 6.2% ...
(Date:10/22/2014)... , Oct. 21, 2014  Early symptoms ... subtle or unnoticed, but new technology, coupled with ... and leading to earlier detection of eye diseases, ... 29 million Americans. If left untreated, these diseases ... blindness. Recently, optometric researchers have ...
(Date:10/22/2014)... NEW YORK , Oct. 22, 2014 ... an August 2014 report by Global Research & Data ... 6.2% per year from 2014 through 2018, as demand ... United States is the world,s largest market ... market with advanced thermometers is Sanomedics International Holdings, Inc. ...
Breaking Medicine Technology:Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 2Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 3Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 4Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 2Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 3Sanomedics International Holdings Analyst Report: Taking Some Heat by BrokerBank Securities, Inc. 2
... /PRNewswire-Asia/ -- ShangPharma Corporation (NYSE: SHP ) ... biotechnology research and development outsourcing company, today announced that ... growing capacity needs of one of its largest customers, ... it has signed a multi-year extension of its contract ...
... 10, 2012 Reportlinker.com announces that ... available in its catalogue: ... Market Outlook in BRICS (Brazil, Russia, ... http://www.reportlinker.com/p0750215/Magnetic-Resonance-Imaging-MRI-Systems-Market-Outlook-in-BRICS-Brazil-Russia-India-China-South-Africa-to-2017.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Imaging ...
Cached Medicine Technology:ShangPharma Announces Opening of New Facility to Support Lilly's Pipeline 2ShangPharma Announces Opening of New Facility to Support Lilly's Pipeline 3Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 2Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 3Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 4Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 5Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 6Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 7Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 8Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 9Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 10Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 11Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 12Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 13Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 14Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 15Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 16Magnetic Resonance Imaging (MRI) Systems Market Outlook in BRICS (Brazil, Russia, India, China, South Africa) to 2017 17
(Date:10/22/2014)... October 22, 2014 Best Cheap Hosting ... the world. The site has recently announced that iPower ... supplier for people from around the world. , “iPower ... operation today and is providing various kinds of useful ... company insists on offering excellent customer service and a ...
(Date:10/22/2014)... King of Prussia, PA (PRWEB) October 22, 2014 ... Group, is recognized as an industry leader with over ... industry award winning team leader in the areas related ... In addition, Mr. Carlson is an Editorial Advisory Board ... Group Healthcare Council Educator. Blue Fin Group is ...
(Date:10/22/2014)... Tara Haelle HealthDay Reporter ... among young adult men may lead to increased blood pressure, ... cause a similar rise in blood pressure for young adult ... when young adult women drank lightly or moderately, their risk ... found. "This finding parallels studies in older adult men ...
(Date:10/20/2014)... The newly updated Worldwide Medical Market Forecasts to ... figures and forecasts on the global medical markets. , ... the Worldwide Medical Market Forecasts to 2019 ... the worldwide medical market to reveal key insights into ... for 2010-2019, covering each country market individually, allowing you ...
(Date:10/20/2014)... Columbus, OH (PRWEB) October 20, 2014 ... joined Specialists in Obstetrics & Gynecology of Columbus, Inc., ... specialized women’s healthcare services to more than 100,000 patients ... care though all ages and stages of a women’s ... office locations in Westerville and Dublin. , ...
Breaking Medicine News(10 mins):Health News:Best Cheap Hosting USA Has Recently Announced The Best Cheap Web Hosting Companies In 2014 2Health News:Rich Carlson and Marc Duey to Hold Workshop at CBI’s Specialty Pharmacy and Distribution Networks Conference 2Health News:Binge Drinking May Boost Blood Pressure in Young Men 2Health News:Binge Drinking May Boost Blood Pressure in Young Men 3Health News:Binge Drinking May Boost Blood Pressure in Young Men 4Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 2Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 3Health News:Worldwide Medical Market Forecasts to 2019 a New Research Report Added to ReportsnReports.com 4Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 2Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 3
... One of the leading forensic experts on ... Mulholland, is joining forces with a network of ... facing the United States today.Collaborating with top toxicologists, ... and construction specialists and individuals with laboratory and ...
... 50% Drop in Mexico Hotel Search but 30% Increase in ... Poll Says Nearly One in Four Consider Safeguarding with Mask ... the world,s most popular and largest travel community, today announced ... Caribbean hotels, presumably in light of the recent ...
... In celebration of Asian Pacific Islander Heritage Month, SEIU-UHW ... Fresno on Saturday, May 2. The event is designed ... information about the various community organizations that provide services ... Access Program, and the Fresno Health Consumer Center.KQEQ -- ...
... Excelsior Medical Corporation, a leading medical device manufacturer headquartered ... 510 (k) clearance to sell their SwabCap(TM) Luer Access ... the caregiver and protect the patient by disinfecting their ... maintaining antiseptic conditions between line accesses - all in ...
... Calif., May 1 Managed Pharmacy Care, Inc., is ... represents but the general public in several matters of ... order programs in various counties, but it is pleased ... investigating yet another health-care crisis striking our country. For ...
... to Compile International Laws, RulesWASHINGTON, May 1 As ... close eye on pharmaceutical safety doesn,t end with government ... of the blood thinner heparin made in China were ... to treat arthritis. The contaminated heparin caused dozens of ...
Cached Medicine News:Health News:Toxic Chinese Drywall Experts Join Forces to Find Remedial Solutions for Homeowners 2Health News:Photos: Traveler Interest Shifts From Mexico to the Caribbean in Light of Swine Flu 2Health News:Photos: Traveler Interest Shifts From Mexico to the Caribbean in Light of Swine Flu 3Health News:Excelsior Medical Corporation Receives FDA Approval to Market SwabCap(TM) Luer Access Valve Disinfection Cap 2Health News:New FDLI Book Maps Out Pharmacovigilance Provisions in More Than a Dozen Countries 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: