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Trius Antibiotics to be Highlighted in 18 Presentations at ICAAC/IDSA
Date:10/19/2008

tor

-- F1-337: In Vivo Efficacy of Rx100472, A Novel Methionyl-tRNA Synthetase

(MetRS) Inhibitor

Sunday, October 26th

(Poster Session 92, 11:15 am - 12:15 pm)

-- A-985: Pharmacodynamics of TR-701 in a Mouse Thigh Infection Model

Against S. aureus ATCC 33591, a Methicillin-Resistant Isolate

Monday, October 27th

(Poster Session 196, 11:15 am - 12:15 pm)

-- F1-2060: MICs of TR-700, the Active Moiety of the Novel Oxazolidinone

Prodrug TR-701, for Linezolid-Susceptible and - Resistant Enterococci

and Staphylcocci

-- F1-2061: TR-700, a Novel Oxazolidinone, Tested Against

Linezolid-Resistant Gram-Positive Species with Well-Characterized

Resistance Mechanisms

-- F1-2062: In Vitro Pharmacodynamics of TR-700, the Active Moiety of

Prodrug TR-701, a Novel Oxazolidinone, in a Kill-Curve Model

-- F1-2063: Human Pharmacokinetics of TR-700 after Ascending Single Oral

Doses of the Prodrug TR-701, a Novel Oxazolidinone Antibiotic

-- F1-2064: Human Pharmacokinetics of TR-700 after Multiple Oral Doses of

200 and 400 mg of TR-701, a Novel Oxazolidinone Antibiotic

-- F1-2065: In Vitro and In Vivo Efficacy of TR-701 and TR-700 Versus the

Linezolid- and Methicillin-Resistant Staphylococcus aureus cfr Strain

CM/05

-- F1-2066: Demonstration of TR-701 Efficacy in a Mouse Inhalation Anthrax

Model

-- F1-2067: Absence of a Pressor Response to Oral Tyramine in Conscious

Telemeterized Rats Treated with the Novel Oxazolidinone TR-701:

Comparison to Linezolid

-- F1-2068: Quality Control Parameters for TR-700 Broth Microdilution

Susceptibility Tests

-- F1-2069: Relative Potency of TR-700, the Active Moiety of Prodrug

TR-701, Against Selected Bacterial Pathogens and Provisional Disk Test

Criteria

-- F1-2
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SOURCE Trius Therapeutics, Inc.
Copyright©2008 PR Newswire.
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