Navigation Links
Treatment With VP20621 (Non-Toxigenic Clostridium difficile; NTCD) In A Phase 2 Study Resulted In High Rates Of Colonization And Statistically Significant Reductions In Recurrence Of C. difficile Infection
Date:4/22/2013

nd fractured a hip; death was attributed to renal failure and pulmonary sepsis.

"I am thrilled by the data from this Phase 2 study of VP20621, which confirm the therapeutic potential of non-toxigenic C. difficile," commented Dale Gerding , MD, Professor of Medicine at Loyola University Chicago Stritch School of Medicine and research physician at the Hines VA Hospital. "For the first time, we have been able to mimic the protective effect we have inferred from observing natural colonization of patients with non-toxigenic strains of C. difficile. As a clinician on the front lines of CDI research, I find these data to be extremely promising and suggestive of a novel approach to prevention of not only disease recurrence, but primary CDI as well."

Next steps
ViroPharma will complete the evaluation of these Phase 2 data which will help determine a future development pathway. The company reminds its investors that VP20621 was flagged as a non core asset at its September investor event. With these compelling Phase 2 clinical results, we will seek a partner to complete the development and commercialization of the asset.

About VP20621
Antibiotics including those used to treat acute C. difficile infection (CDI) disrupt the normal gastrointestinal flora which renders individuals susceptible to C. difficile colonization. Orally-dosed liquid VP20621 utilizes non-toxigenic spore-based technology as a potential means of recolonization and protection. The goal of VP20621 dosing following antibiotic exposure is to colonize with this non-toxigenic strain of C. difficile and to prevent colonization by toxigenic strains, thereby preventing disease. VP20621 may have therapeutic utility in the prevention of recurrence following treatment of acute CDI and in the primary prevention of CDI. ViroPharma acquired VP20621 in 2006, through a licensing agreement with Dr.
'/>"/>

SOURCE ViroPharma Incorporated
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Study Finds Utilizing Integrated Medical and Pharmacy Data Improves Ability to Forecast Use of High-cost Specialty Treatments
2. Aethlon Medical Note: An Unprecedented Data Point, The Single-Treatment Capture of Hepatitis C Virus (HCV) by the Aethlon Hemopurifier®
3. Onyx Pharmaceuticals Announces FDA Advisory Committee to Review Carfilzomib for the Treatment of Patients with Relapsed and Refractory Multiple Myeloma
4. Accuray Launches First Study to Compare CyberKnife® SBRT to Surgery and IMRT for Treatment of Early-Stage Prostate Cancer
5. Elekta, pioneer in treatment of cancer in brain disorders, to Move North America Headquarters to Atlanta
6. Ampio Awarded US and Canadian Patents that will Bolster the Commercialization of Optina™ for the treatment of Diabetic Macular Edema (DME)
7. National Patient Advocate Foundation Praises Signing of the Delaware Cancer Treatment Access Act into Law
8. Zogenix Submits New Drug Application (NDA) to U.S. Food and Drug Administration (FDA) for Zohydro™ for Treatment of Chronic Pain
9. Janssen Research & Development Submits XARELTO® (rivaroxaban) to U.S. FDA for the Treatment and Prevention of Recurrent Venous Thromboembolism
10. Study Results Demonstrate Analytical Treatment Interruption to Assess Antiviral Activity of Argoss Arcelis™ Personalized Immunotherapy for Treatment of HIV Patients, AGS-004, Is Acceptable Strategy for At Least 16 Weeks
11. Alder BioPharmaceuticals Inc. Initiates Phase 1 Clinical Study of Antibody Therapeutic Candidate for Treatment of Migraine, ALD403
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/18/2014)... , Oct. 18, 2014  In a ... Campaign (HRC), the nation,s largest lesbian, gay, bisexual ... the use of Truvada for Pre-Exposure Prophylaxis (PrEP). ... used to prevent the spread of a disease ... only brand name anti-HIV drug combination currently approved ...
(Date:10/17/2014)... UBM Medica US announces that Neurology Times ... for neurologists and other healthcare providers, features special coverage on ... discussions of the latest developments in approaches to diagnosis. ... , more than the total of those who have multiple ... can be difficult because there are no confirmatory medical tests. ...
(Date:10/17/2014)... MONICA, Calif. , Oct. 17, 2014 A ... Orange County doctor with a history of ... television ad for Yes on Prop 46 today, highlighting how ... random drug and alcohol testing. The ad ... goes off reading "911-Report To ER."  Proposition 46 will enact ...
Breaking Medicine Technology:HRC Endorses PrEP, Calls for Bold Action to Expand Access to Anti-HIV Drug 2HRC Endorses PrEP, Calls for Bold Action to Expand Access to Anti-HIV Drug 3Neurology Times Features Coverage of Parkinson and Alzheimer Disease 2Neurology Times Features Coverage of Parkinson and Alzheimer Disease 3Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 2Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 3Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 4
(Date:10/19/2014)... 19, 2014 Visual Impact Frequency ... just been released to the public generating a ... building and fitness community. The commotion surrounding the ... Vin Delmonico prompting an investigative review. , "Many ... what is commonly known as a training 'plateau' ...
(Date:10/19/2014)... stem cell-based research could improve understanding of intestinal diseases ... suggests. Scientists used stem cells to grow "organoids" ... They then transplanted the organoids into mice, creating a ... researchers. "This provides a new way to study ... failure, from genetic disorders appearing at birth to conditions ...
(Date:10/19/2014)... OCTOBER 20, 2014 – The U.S. Government has ... treat Alzheimer,s disease by 2025. However, a workgroup ... the research milestones in the U.S. Government,s National ... in scope, increased in scale, and adequately funded ... series of proposals by the workgroup to enlarge ...
(Date:10/19/2014)... NY (PRWEB) October 19, 2014 Nearly ... Bard Inc. and Johnson & Johnson’s Ethicon unit have ... Court, where two state proceedings are continuing to move ... 7,201 lawsuits have been filed over products part of ... Case List updated on October 11th, 2014, which showed ...
(Date:10/19/2014)... Denver, Colorado (PRWEB) October 19, 2014 ... consider joining Colorado and Washington State in the outright ... some words of advice for pro-cannabis activists in those ... framework is in place, or prepare for chaos. , ... The Denver-based shop is one of Colorado’s first recreational ...
Breaking Medicine News(10 mins):Health News:Visual Impact Frequency Training Review: Rusty Moore's Latest Fitness Guide Released 2Health News:Scientists Grow, Implant Human Intestinal Tissue in Mice 2Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 2Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 3Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 4Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 5Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 6Health News:Transvaginal Mesh Litigations in New Jersey Tally More than 8,700 Lawsuits against C.R. Bard and Ethicon, Bernstein Liebhard LLP Reports 2Health News:Transvaginal Mesh Litigations in New Jersey Tally More than 8,700 Lawsuits against C.R. Bard and Ethicon, Bernstein Liebhard LLP Reports 3Health News:Transvaginal Mesh Litigations in New Jersey Tally More than 8,700 Lawsuits against C.R. Bard and Ethicon, Bernstein Liebhard LLP Reports 4Health News:Cannabis CEO Warns Those States Considering a Legal Marijuana Market to Do Their Homework First 2Health News:Cannabis CEO Warns Those States Considering a Legal Marijuana Market to Do Their Homework First 3
... WASHINGTON, May 9, 2011 Flakes of skin that people ... are not just a nuisance the source of dandruff, ... actually can be beneficial. A new study, published in the ... concludes that oil in those skin cells makes a small ...
... 2011) The John Theurer Cancer Center at Hackensack ... Symposium on Friday, May 20 from 7:30am - 1:00pm. ... latest neuro-oncology trends by leaders in the field. ... to bring together leaders in neuro-oncology to provide insights ...
... out in Valencia shows that 37.4% of children aged from 6 to ... those aged from 12 to 15 wake up feeling refreshed only once ... 4.26% of them fall asleep in class more than three times per ... sleep throughout our lives depends on how we learn to sleep as ...
... invaluable procedure for detecting problems in the colon and ... catch the warning signs of colorectal cancer. Perfecting the ... just how much practice makes perfect? That was ... Clinic research team set out to answer in their ...
... , SUNDAY, May 8 (HealthDay News) -- People ... the disorder, even if they show no symptoms, a new ... digestive problems in the small intestine when the person consumes ... number of U.S. residents with the disease has grown rapidly ...
... HealthDay Reporter , MONDAY, May 9 (HealthDay News) ... often get unneeded CT scans that expose them to high ... the outcomes of more than 40,000 children treated for minor ... 2004 and September 2006. They found that four to six ...
Cached Medicine News:Health News:The skinny on how shed skin reduces indoor air pollution 2Health News:The John Theurer Cancer Center to host Seventh Annual Neuro-Oncology Symposium 2Health News:One-third of Spanish children do not wake up feeling refreshed 2Health News:Mayo Clinic studies how much practice makes perfect when performing colonoscopies 2Health News:More People May Benefit From Going Gluten-Free 2Health News:Child's Head Injury Doesn't Always Need CT Scan: Study 2Health News:Child's Head Injury Doesn't Always Need CT Scan: Study 3
... The Seal-Away CS and ... are designed for the introduction ... the coronary sinus from a ... St. Jude Medical's outstanding peel-away ...
... Medtronic has been a key participant ... for more than a decade. Previous Medtronic ... for concentrated platelets, as well as to ... for producing platelet-rich plasma (PRP) for a ...
The AXIUS™ Blower/Mister provides controlled delivery of CO2 and saline to improve visibility during anastomosis....
... The SJM Pericardial Patch with EnCap ... great vessel reconstruction/repair and for pericardial ... and offers surgeons durability and flexibility, ... synthetic patches. Equally important in a ...
Medicine Products: