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Transparency Life Sciences Partners With Oncology Researchers At Icahn School Of Medicine At Mount Sinai To Assess Metformin In Prostate Cancer
Date:11/19/2013

NEW YORK, Nov. 19, 2013 /PRNewswire/ -- Transparency Life Sciences, LLC (TLS), the world's first drug development company based on open innovation, today announced that it is collaborating with Dr. Matthew Galsky, Associate Professor of Medicine, Division of Hematology/Oncology at the Icahn School of Medicine at Mount Sinai, to design and conduct a pilot trial assessing metformin as a potential treatment for prostate cancer. Metformin is a widely prescribed diabetes drug that has shown promising activity against prostate and other cancers in preclinical and clinical studies.

A second objective of the trial is to test the feasibility of using crowdsourcing to obtain broad-based input to the design of the clinical protocol and telemonitoring to replace most patient site visits, with the aim of increasing participation in cancer trials through greater engagement and by reducing the burden on patients. Crowdsourcing and telemonitoring are key elements of TLS's drug development strategy. TLS is partnering with AMC Health, a comprehensive provider of telehealth services, to conduct the metformin study.

Dr. Galsky commented, "One goal of this pilot study is to obtain a preliminary assessment of whether metformin can affect rising prostate specific antigen (PSA) levels in men who have been treated for localized prostate cancer. A second goal is to test whether it is feasible to conduct a cancer trial that incorporates crowdsourcing into the study design and uses telemonitoring to eliminate most patient site visits. Our prior research demonstrates that cancer trials are highly inefficient and geographically inaccessible to a large proportion of cancer patients. We are optimistic that a greater number of patients would participate if they were more engaged in the process and the burden of site visits were reduced."

"This study fits the TLS model perfectly," noted '/>"/>

SOURCE Transparency Life Sciences, LLC
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