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Transdermal Drug Delivery - Technologies, Markets, and Companies
Date:1/3/2012

croneedle Array Patch technology 49

Macroflux microprojections technology 49

Companies developing microneedles for transdermal drug delivery 49

Needlefree injections 50

Glide SDI® solid dose injector 50

Jet injection 50

Mini-Ject needlefree delivery system 51

MicroJet for painless injections 51

Nanoliter-volume pulsed microjets 51

SUMAVEL™ DosePro™ needle-less injection 52

Skin ablation or abrasion for drug delivery 52

Nanotechnology-based transdermal drug delivery 52

Nanoparticles and nanoemulsions for skin disorders 53

Transdermal nanoparticle preparations for systemic effect 53

Nanotechnology-based transdermal vaccination and immunotherapy 54

Delivery of nanostructured drugs from transdermal patches 54

NanoCyte transdermal drug delivery system 54

Effect of mechanical flexion on penetration of bucky balls through the skin 55

Safety issues of applications of nanomaterial carriers on the skin 55

Comparison of transdermal drug delivery systems 55

Role of microelectronics in transdermal drug delivery 56

Transdermal drug design 56

In vitro testing of transdermal drug delivery systems 56

In vivo testing of drug delivery systems 57

Infrared spectroscopy for evaluation of transdermal drug delivery 58

Modeling of transport through the skin 58

Concluding remarks on transdermal drug delivery technologies 59

Future developments in transdermal drug delivery 59

3. Transdermal Therapeutics 61

Introduction 61

Drugs that can be administered transdermally 61

Skin disorders 64

Psoriasis 64

Nanoemulsions for paclitaxel delivery in psoriasis 64

Iontophoresis for treatment of psoriasis 64

Hair loss 64

Cardiovascular disorders 65

Angina pectoris 65

Transdermal drug delivery for hypertension 66

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3. Transdermal Drug Delivery - Technologies, Markets, and Companies
4. Zosano Pharma, Inc. and Asahi Kasei Pharma Corporation Enter Exclusive Licensing Agreement for a Weekly Transdermal Patch Formulation of Teribone™ (teriparatide acetate) for Osteoporosis
5. Results of a Pivotal Phase 3 Efficacy and Safety Study for Butrans® (Buprenorphine) Transdermal System CIII Published in The Journal of Pain
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