Navigation Links
Transdel Pharmaceuticals Presents Phase 3 Study Data on Ketotransdel® at World Pain Congress in Montreal, Canada
Date:9/2/2010

, I am impressed by the excellent cutaneous/application site tolerability."

The presented poster titled "EFFICACY AND SAFETY OF KETOPROFEN 10% CREAM IN THE TREATMENT OF PAIN ASSOCIATED WITH ACUTE SOFT TISSUE INJURIES (PHASE 3 STUDY TDLP-110-001)" summarizes the key efficacy data from Intent-to-treat (ITT) analysis and safety data of all patients randomized. In agreement with statistical (ICH-E9) guidelines a total of 35 patients were excluded from the original ITT population of 361 patients since they did not meet study entry criteria and should not have been enrolled based on information that was not known at the time of enrollment.  This modified ITT (mITT) population included 326 patients.

Using the primary endpoint, which was the change from baseline in pain intensity during daily activity over the previous 24 hours at the Day 3 visit, the study demonstrated statistical significance (p=0.038) in the mITT population and approached statistical significance (p=0.087) in the original ITT population. Pain during activity scored 3 times daily by patients over seven days also supports the primary endpoint by demonstrating a consistent separation between the TDLP-110 and placebo groups over time, and showed statistical significance between the two groups in the ITT analyses.

The proportion of patients who were satisfied with the treatment and achieved moderate or higher pain relief - as recorded on a seven-point Likert Scale - was greater with TDLP-110 (p=0.023). Time to onset of meaningful pain relief was assessed and was about 40 minutes faster in TDLP-110 treated patients.  Time to end of meaningful analgesic effect was about 45 minutes longer in the TDLP-110 treated group.  

TDLP-110 demonstrated excellent safety and tolerability with a low overall incidence (18.1% vs. placebo 20.3%) of adverse events (AEs) and no treatment related gastrointestinal, cardiovascular, hepatic or other clinically relevant AEs. The incidence of
'/>"/>

SOURCE Transdel Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Transdel Pharmaceuticals Announces Management Reorganization
2. Transdel Pharmaceuticals to Webcast Presentation at 4th Annual BIOCOM Investor Conference
3. Transdel Enrolls First Patient for Ketotransdel(TM) Phase 3 Clinical Trial
4. Transdel Initiates Ketotransdel(TM) Phase 3 Clinical Program for Pain
5. Transdel Pharmaceuticals Advances Lead Topical Pain Drug into Phase 3 Program
6. Optimer Pharmaceuticals Announces Presentations of Additional Fidaxomicin Phase 3 Data at Upcoming ICAAC Annual Meeting
7. Optimer Pharmaceuticals to Present at September 2010 Investor Conferences
8. Pfizer to Acquire FoldRx Pharmaceuticals
9. Reportlinker Adds The Market for Pharmaceuticals in Brazil, Russia, India & China
10. Reportlinker Adds The Outlook for Pharmaceuticals In The Middle East And North Africa To 2015
11. Webcast Alert: Isis Pharmaceuticals Hosts Expert Panel Conference Call to Discuss Mipomersen Data Presented at the ESC Congress 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... 2014  CryoLife, Inc. (NYSE: CRY ), ... on cardiac and vascular surgery, announced today that ... Officer, has been elected to the Company,s Board of ... G. Anderson , Executive Chairman of CryoLife, stated, "Since joining ... an excellent leader who is well positioned to maximize ...
(Date:10/22/2014)... 2014 Oramed Pharmaceuticals Inc. ... pharmaceutical company focused on the development of oral ... results from its Phase IIa clinical trial of ... treat type 1 diabetes. The trial was conducted in ... a U.S. Food and Drug Administration (FDA) Investigational ...
(Date:10/22/2014)... , Oct. 21, 2014  Early symptoms of ... or unnoticed, but new technology, coupled with yearly, ... leading to earlier detection of eye diseases, including ... million Americans. If left untreated, these diseases can ... Recently, optometric researchers have deployed ...
Breaking Medicine Technology:Pat Mackin Joins CryoLife Board of Directors 2Pat Mackin Joins CryoLife Board of Directors 3Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 2Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 3Oramed Pharmaceuticals Reports Positive Top-Line Data from U.S. Phase IIa Trial with Oral Insulin in Type 1 Diabetes 4Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 2Technology Advancements Enhance Early Detection of Eye Diseases Associated with Diabetes 3
... ADA,s 2009 Convention -- When Shawnae Jebbia won the Miss ... fairytale career. She appeared at events throughout the world, worked ... Shawnae,s world unexpectedly changed when she was diagnosed with hearing ... she had a difficult time understanding and accepting the sudden ...
... Oct. 29 Mettler-Toledo International Inc. (NYSE: MTD ) today announced ... , Sales in local currency declined by 12% in ... negative currency impact. , Net earnings per diluted ... third quarter of 2008. Adjusted EPS was $1.36, a 6% ...
Cached Medicine Technology:Former Miss USA Shawnae Jebbia Shines with Siemens Pure 2Former Miss USA Shawnae Jebbia Shines with Siemens Pure 3Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 2Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 3Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 4Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 5Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 6Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 7Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 8Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 9Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 10Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 11Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 12Mettler-Toledo International Inc. Reports Third Quarter 2009 Results 13
(Date:10/20/2014)... 20, 2014 With a mere 19 ... Crist made a brief fundraising stop at the ... , Fresh from a debate last night with his ... stage for the first seven minutes because Crist had ... described the incident in one word: "weird." , Before ...
(Date:10/20/2014)... The Advocator Group, LLC is proud ... for Suicide Prevention’s (AFSP) Out of the Darkness walk ... that hosts hundreds of community walks throughout the country ... to help understand and prevent suicide through not only ... , The Advocator Group shares this passion for ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 Women’s health ... in Obstetrics & Gynecology of Columbus, Inc., A Division ... healthcare services to more than 100,000 patients annually. Dr. ... all ages and stages of a women’s life. She ... locations in Westerville and Dublin. , Dr. Murphy ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 hc1.com ... a secure cloud solution that enables healthcare organizations ... the ultimate healthcare-specific customer relationship management (“CRM”) solution. ... the unique needs of the healthcare industry, the ... for providers and patients by combining healthcare CRM, ...
(Date:10/20/2014)... Angeles, CA (PRWEB) October 20, 2014 ... fitness expertise, nutritional coaching, corporate wellness programming, authorship, international ... CPT, is excited to announce the release of the ... , After many years of coaching thousands of individuals ... nutrition tracking app that does not require calorie counting ...
Breaking Medicine News(10 mins):Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 2Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 3Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 2Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 3Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 2Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 3Health News:Healthcare Relationship Management (HRM) Leader hc1.com® Launches hc1® Quick Start™ 2Health News:JZ Fitness Nutrition App Launches on iTunes 2Health News:JZ Fitness Nutrition App Launches on iTunes 3
... Erica Davis, Subject ... and Heart Disease , ... CA (PRWEB) May 17, 2010 -- One of the race participants in this year’s Strawberry ... That person is Erica Davis., , , , , ,Since a one-in-five-million genetic anomaly left ...
... defence mechanism against heart disease could be switched on by ... University of Leeds. The University of Leeds biologists have ... can limit the production of inflammatory cytokines proteins that ... found that this protective effect can be triggered by pregnenolone ...
... had depression, substance abuse in youth, study finds , ... psychological disorders such as depression and substance abuse appear ... research suggests. , Those who experience mental health difficulties ... maximize their educational opportunities, and they are also likely ...
... ... how to achieve the highest conversion performance. , ... Encino, CA (PRWEB) May 14, 2010 -- T3Leads, a ... marketing industry. Founded in 2006, T3Leads has since provided unparalleled performance and cutting-edge efficiency ...
... ... is once again pleased to announce that a superb physician has joined the Practice — ... ... LLP (ENTA) is once again pleased to announce that a superb physician has joined the ...
... study published last week in Archives of Internal Medicine ... lowered total and LDL-cholesterol levels, in addition to triglycerides. ... counties, is the most comprehensive study of its kind and ... risk of cardiovascular disease. The report, authored by Dr. ...
Cached Medicine News:Health News:First Paraplegic Woman to Climb Mt. Kilimanjaro to Race at Vista's Strawberry Festival 2Health News:'Fountain of youth' steroids could protect against heart disease 2Health News:Kids' Psychological Problems Have Long-Term Effects 2Health News:T3Leads Provides Latest Industry News: Imperative Information to Help Publishers Maximize Profits 2Health News:T3Leads Provides Latest Industry News: Imperative Information to Help Publishers Maximize Profits 3Health News:ENT and Allergy Associates Welcomes Tamekia L. Wakefield, MD, Further Reinforcing its Pediatric Sinus Expertise and Capabilities in Queens , , 2Health News:ENT and Allergy Associates Welcomes Tamekia L. Wakefield, MD, Further Reinforcing its Pediatric Sinus Expertise and Capabilities in Queens , , 3Health News:Pistachios: A handful a day may keep the cardiologist away 2
Symbia T, a TruePoint SPECTCT system, combines a dual-detector variable angle gamma camera with a CT scanner optimized for rapid, accurate attenuation correction of the nuclear data....
... analyzer and data management system ,RADIANCE ... traditional needs of data management systems (DMS), ... management of STAT analyzer systems., ,The RADIANCE ... solution for both STAT analyzers and hospital ...
... is a comprehensive IT solution that ... admission to follow-up. This scalable solution ... diagnostic tools from syngo Dynamics with ... longitudinal clinical repository that becomes a ...
... the AXIOM Artis dBC Magnetic Navigation ... navigation system equipped with digital flat ... is uniquely capable of improving the ... to facilitate increased efficiency and productivity ...
Medicine Products: