Navigation Links
Transdel Pharmaceuticals Presents Phase 3 Study Data on Ketotransdel® at World Pain Congress in Montreal, Canada
Date:9/2/2010

, I am impressed by the excellent cutaneous/application site tolerability."

The presented poster titled "EFFICACY AND SAFETY OF KETOPROFEN 10% CREAM IN THE TREATMENT OF PAIN ASSOCIATED WITH ACUTE SOFT TISSUE INJURIES (PHASE 3 STUDY TDLP-110-001)" summarizes the key efficacy data from Intent-to-treat (ITT) analysis and safety data of all patients randomized. In agreement with statistical (ICH-E9) guidelines a total of 35 patients were excluded from the original ITT population of 361 patients since they did not meet study entry criteria and should not have been enrolled based on information that was not known at the time of enrollment.  This modified ITT (mITT) population included 326 patients.

Using the primary endpoint, which was the change from baseline in pain intensity during daily activity over the previous 24 hours at the Day 3 visit, the study demonstrated statistical significance (p=0.038) in the mITT population and approached statistical significance (p=0.087) in the original ITT population. Pain during activity scored 3 times daily by patients over seven days also supports the primary endpoint by demonstrating a consistent separation between the TDLP-110 and placebo groups over time, and showed statistical significance between the two groups in the ITT analyses.

The proportion of patients who were satisfied with the treatment and achieved moderate or higher pain relief - as recorded on a seven-point Likert Scale - was greater with TDLP-110 (p=0.023). Time to onset of meaningful pain relief was assessed and was about 40 minutes faster in TDLP-110 treated patients.  Time to end of meaningful analgesic effect was about 45 minutes longer in the TDLP-110 treated group.  

TDLP-110 demonstrated excellent safety and tolerability with a low overall incidence (18.1% vs. placebo 20.3%) of adverse events (AEs) and no treatment related gastrointestinal, cardiovascular, hepatic or other clinically relevant AEs. The incidence of
'/>"/>

SOURCE Transdel Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Transdel Pharmaceuticals Announces Management Reorganization
2. Transdel Pharmaceuticals to Webcast Presentation at 4th Annual BIOCOM Investor Conference
3. Transdel Enrolls First Patient for Ketotransdel(TM) Phase 3 Clinical Trial
4. Transdel Initiates Ketotransdel(TM) Phase 3 Clinical Program for Pain
5. Transdel Pharmaceuticals Advances Lead Topical Pain Drug into Phase 3 Program
6. Optimer Pharmaceuticals Announces Presentations of Additional Fidaxomicin Phase 3 Data at Upcoming ICAAC Annual Meeting
7. Optimer Pharmaceuticals to Present at September 2010 Investor Conferences
8. Pfizer to Acquire FoldRx Pharmaceuticals
9. Reportlinker Adds The Market for Pharmaceuticals in Brazil, Russia, India & China
10. Reportlinker Adds The Outlook for Pharmaceuticals In The Middle East And North Africa To 2015
11. Webcast Alert: Isis Pharmaceuticals Hosts Expert Panel Conference Call to Discuss Mipomersen Data Presented at the ESC Congress 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... , Aug. 27, 2014 Reportbuyer.com ... Co-development Terms & Agreements in ... https://www.reportbuyer.com/product/2276221/Co-development-Terms--Agreements-in-Pharma-Biotech-and-Diagnostics.html The Co-development Terms ... report provides comprehensive understanding and unprecedented access ... into by the worlds leading life science ...
(Date:8/27/2014)... 2014 About 8 million Americans have peripheral ... of fatty plaque in the arteries, according to recent ... and in incidences of diabetes and obesity, the ... Extremity Arterial RevascularizatioN (LEARN) meeting, Oct. 9–11 in ... interested residents and fellows will be able to gain ...
(Date:8/27/2014)... Varian Medical Systems (NYSE: VAR) today broke ground on ... Lake City manufacturing facility and allow for the ... to ultimately create 1,000 new full time jobs ... " Utah is home to hardworking ... can be credited with Varian,s success in the manufacturing of ...
Breaking Medicine Technology:Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 2Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 3Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 4Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 5Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 6Co-development Terms & Agreements in Pharma, Biotech and Diagnostics 7LEARN to Treat Peripheral Arterial Disease Patients 2LEARN to Treat Peripheral Arterial Disease Patients 3Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 2Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 3Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 4
... Israel, Feb. 8, 2011 2P2D Ltd ., a ... today announced that it has appointed Mr. Tovi Bachar, former ... Tovi Bachar has completed seven years as Managing ... Systems, a leading diagnostic imaging equipment company. In 2008, Tovi ...
... Technologies (OTC Bulletin Board: PSTX ), today ... Annual Institutional Investor Conference in New York City at ... on, March 1, 2011 at 11:20 AM Eastern. Through ... provides a proven solution for improving patient safety and ...
Cached Medicine Technology:Patient Safety Technologies to Present at 22nd Annual Institutional Investor Conference 2
(Date:8/27/2014)... Lauderdale, FL (PRWEB) August 27, 2014 ... cost-effective money-saving dental plans, has launched in the ... consumers access to quality, affordable dental care services ... leading destination for Tennessee consumers looking to save ... reduced-fee dental rates as a member of discount ...
(Date:8/27/2014)... For those who want to build ... products are very practical. Top10BestSEOHosting.com today announces that ... the best ASP.NET hosting suppliers of this year. ... top web hosting provider for a long time, ... today. Recently proclaimed one of the fastest growing ...
(Date:8/27/2014)... Philadelphia, PA. Inc. magazine ranked Holganix ... list, an exclusive ranking of the nation’s fastest-growing privately ... at the most important segment of the economy - ... exposure as members of the Inc. 500 list include ... “Some of world’s greatest companies have had their start ...
(Date:8/27/2014)... Altena, AR (PRWEB) August 27, 2014 ... in August 2014, is about Seed Digging, which a ... mental health therapy models, yet works to bring permanent ... people with addictions and mental health disorders cured on ... clutter from their own minds and find incredible inner ...
(Date:8/27/2014)... August 28, 2014 Recently, iFitDress.com, a ... announced its new designs of romantic bridal gowns ... enjoy a promotional price (up to 66 percent off) ... the company’s product line has been updated with these ... and patient. iFitDress.com hopes that all clients can gain ...
Breaking Medicine News(10 mins):Health News:DentistSave.com Launches Discount Dental Plans in Tennessee for Consumers, Businesses, and Groups 2Health News:DentistSave.com Launches Discount Dental Plans in Tennessee for Consumers, Businesses, and Groups 3Health News:Top10BestSEOHosting.com Releases the Best ASP.NET Hosting Suppliers of This Year: Hostgator, Arvixe and FatCow 2Health News:Inc Magazine Unveils 33rd Annual List of America's Fastest-Growing Private Companies - the Inc. 500 2Health News:Shawna Burns, Counselor, Releases Debut Book, "Seed Digging," to Improve Lives of Children and Adults with Addictions and Mental Health Disorders 2Health News:Promotion For Romantic Bridal Gowns Launched By Professional Company iFitDress.com 2
... debilitating headaches, researchers say, , , MONDAY, March 9 (HealthDay News) ... migraines, it might not be all in your head. , ... are more likely to visit emergency rooms with migraines if ... effect, too, although it is not as significant. , The ...
... SplashPLEASANT GROVE, Utah, March 9 What,s in a ... www.myomed.com ), names like Tom Brady, LaDainian Tomlinson, Willie ... helping people. Endorsements by professional athletes of this caliber ... actually used the product for a couple of years ...
... Western Reserve University School of Medicine Department of Ophthalmology ... along with three individual awards that could total up ... (RPB) Foundation. These are the most grants awarded in ... sciences program since 1997. In that time, the program ...
... Time to World,s Largest Breast Cancer Organization Founded in Her ... the global breast cancer movement 29 years ago by promising ... of the disease, that she would do everything in her ... tenure as U.S. Chief of Protocol has ended, Ambassador Brinker ...
... Borrowing from the iconic I Love NY logo, Ogilvy ... in a new campaign logo for the American Red Cross ... designed to recruit New Yorkers to become Red Cross Reserve ... of Governor David Paterson -- is part of a multi-channel ...
... Martin,s Ashley Treatment Center in MarylandHAVRE DE GRACE, Md., ... noted authority and lecturer on alcoholism who co-founded Father ... Grace, MD, died today at his home in Havre ... lectures on alcoholism as a disease, delivered to alcoholics ...
Cached Medicine News:Health News:Warmer-Than-Average Temperatures Raise Migraine Risk 2Health News:Warmer-Than-Average Temperatures Raise Migraine Risk 3Health News:Tom Brady Endorsed Pain Cream Returns to Natural Products Expo 2Health News:Case Western Reserve awarded nearly $1 million from Research to Prevent Blindness Foundation 2Health News:Susan G. Komen for the Cure(R)'s Founder, Nancy G. Brinker, Reengages With Organization Following Tenure as U.S. Chief of Protocol 2Health News:American Red Cross of Greater New York Launches New Effort to Recruit 10,000 Disaster Volunteers 2Health News:American Red Cross of Greater New York Launches New Effort to Recruit 10,000 Disaster Volunteers 3Health News:The Rev. Joseph C. Martin, Leading Authority on Alcoholism and Addiction Treatment, Dies at 84 2Health News:The Rev. Joseph C. Martin, Leading Authority on Alcoholism and Addiction Treatment, Dies at 84 3Health News:The Rev. Joseph C. Martin, Leading Authority on Alcoholism and Addiction Treatment, Dies at 84 4
... graphic display and IOL power calculation software. ... include firmware module with SRKII, SRKT, Holladay ... tones increase in frequency the closer you ... alignment is achieved with corneal indentation. Triple ...
The CryoSurgery console is the control center for CryoCath's surgical probe. It is a modular system made up of a console control unit and a tank dolly system. The system can be used as a unit or in s...
... a malleable, single-use cryosurgical probe developed to ... probe will ablate cardiac tissue while a ... procedure, such as coronary artery bypass grafting ... repair and as part of the Maze ...
The Medtronic CardioRhythm Marinr Catheter is intended for use in diagnostic electrophysiologic procedures. These catheters are designed for recording intracardiac electrograms and temporary pacing a...
Medicine Products: