Navigation Links
Transave Completes Successful Phase II Clinical Program for ARIKACE in the Treatment of Pseudomonas Lung Infections
Date:10/19/2009

dies suggest that ARIKACE has the potential to improve upon the standard of care in the treatment of chronic Pseudomonas lung infections, and further studies are merited in an effort to bring this medicine to market."

In the U.S., ARIKACE was administered once daily for 28 days at 70 mg, 140 mg and 560 mg doses using a novel inhalation device, the eFlow® Electronic Nebulizer (PARI Pharma GmbH). This study included member institutions of the Cystic Fibrosis Foundation's Therapeutics Development Network. In Europe, ARIKACE was administered once daily for 28 days at 280 mg and 560 mg dosages, also using the eFlow® Electronic Nebulizer. Improved lung function was dose-related with the higher 560 mg dose resulting in the greatest improvement in lung function which was sustained for 28 days after treatment ended. Adverse events reported were consistent with those expected in a population of CF patients receiving inhaled medicine, and no differences between groups in the overall rates of adverse events.

"Once-a-day ARIKACE, providing sustained improvement even after therapy ends, suggests that it is possible to treat these stubborn Pseudomonas lung infections while reducing the treatment burden that these patients currently endure," said Dr. Clancy. "Further, the potential for ARIKACE to penetrate the biofilm and achieve a sustained improvement in lung function would be an important advance in this field."

Study results have consistently demonstrated significant reduction in Pseudomonas bacterial density in both mucoid and non-mucoid strains of Pseudomonas. Mucoid strains of Pseudomonas are associated with the presence of biofilms. A biofilm is a protective gel-like barrier formed by colonies of the common and often chronic Pseudomonas bacteria. The bacterial cells encased within the biofilm are difficult to kill because many antibiotics either stick to the surface of the bi
'/>"/>

SOURCE Transave, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Transave Announces Positive Phase II Results For Once-Daily ARIKACE(TM) in the Treatment of Non-CF Bronchiectasis Patients Who Have Pseudomonas Lung Infections
2. Transave Receives $2.2 Million Cystic Fibrosis Foundation Award for Development of ARIKACE(TM)
3. Transave Announces Positive Phase II Results for Once-Daily Arikace(TM) in the Treatment of Cystic Fibrosis Patients Who Have Pseudomonas Lung Infections
4. ProUroCare Medical Completes Multiple Site Clinical Study for Imaging Prostate Abnormalities
5. BMEYE B.V. Completes EUR 6 Million Series B Financing Round
6. Subsidiary of Nova Biomedical Completes Acquisition of Assets of CCS Medicals Subsidiary, Sanvita, Inc.
7. DBMS Consulting Successfully Completes Roll out of Oracle Health Sciences Applications (OHSA) Suite for SIRO Clinpharm
8. Tetraphase Pharmaceuticals Completes Series B Financing to Support the Advancement of Novel Antibiotic Drug Candidates
9. PDL BioPharma Completes October 1 Special Dividend Payment
10. SyntheMed Completes $1.0 Million Equity Placement
11. ThermalTherapeutic Systems Completes $2.75 Million Series A Financing With Originate Ventures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... DALLAS , July 11, 2014 ... report "Scintillator Market by Composition of Material, Application ... and others), End Product (Personal Instrument, Hand-Held Instruments, ... Forecast and Analysis to 2013 - 2020", published by MarketsandMarkets, ... a CAGR of 5.62% from 2014 to 2020, ...
(Date:7/11/2014)... July 11, 2014 On ... down 0.52%, the Dow Jones Industrial Average finished the day ... 1,964.68, down 0.41%. The losses were broad based as eight ... S&P 500 Health Care Sector Index ended the day at ... the last one month. Investor-Edge has initiated coverage on the ...
(Date:7/11/2014)... Show organisers report ... Expo 2014 were a brand new audience ... London , plus a 10% increase ...      (Logo: http://photos.prnewswire.com/prnh/20130723/629764-a) ...      (Photo: http://photos.prnewswire.com/prnh/20140711/696892-b ) ...
Breaking Medicine Technology:Scintillator Market will be worth $479.16 Million by 2020 2Scintillator Market will be worth $479.16 Million by 2020 3Scintillator Market will be worth $479.16 Million by 2020 4Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 4UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 2UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 3UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 4
... Ontario, April 1, 2011 Promius Pharma, LLC, an ... ), and Valeant Pharmaceuticals International, Inc. (NYSE: ... have signed a collaboration agreement for Cloderm® (clocortolone pivalate ... an upfront payment and pay future royalties as the ...
... CarePoint Partners, one of the largest, fastest growing ... launched a food drive today throughout its twenty-one locations ... the communities where it operates. Called the "Got Food?" ... of April. CarePoint Partners is partnering with its healthcare ...
Cached Medicine Technology:Promius Pharma and Valeant Form Collaboration to Market Cloderm® Cream in the United States 2Promius Pharma and Valeant Form Collaboration to Market Cloderm® Cream in the United States 3Promius Pharma and Valeant Form Collaboration to Market Cloderm® Cream in the United States 4CarePoint Partners Kicks Off Food Drive to Help Fight Hunger in Twenty-One Local Communities 2
(Date:7/13/2014)... July 13, 2014 Chromatography system ... components from various types of biological samples such ... the sample mixture into two phase, namely mobile ... mobile phase run over the stationary phase, followed ... components that provide the separation of mixture. Chromatography ...
(Date:7/13/2014)... 13, 2014 Recently, MillionaireCasket.com, a well-known casket ... oak caskets . Additionally, the company’s chief executive officer has ... new oak caskets are offered at discounted prices, from 15 ... concerned, quality caskets are in huge demand in the current ... caskets . We have a lot of high quality products ...
(Date:7/13/2014)... BC (PRWEB) July 13, 2014 Victorian ... excitement by promoting the rental of bikes for its ... historic downtown Victorian Hotel to tour the area using ... plus tax. Bicycle enthusiasts love to call Vancouver home, ... options for cycle travel and picturesque journeys through the ...
(Date:7/13/2014)... The North American water storage systems market is ... million by 2018, at a CAGR of 21.0%, from 2013 ... a rapid pace in North America. The U.S. is experiencing ... & wastewater storage and collection, and the increased spending on ... at a healthy rate in Canada, and is rising at ...
(Date:7/13/2014)... 13, 2014 Micro irrigation systems are ... water dispersal as wells as to maintain soil quality. ... projected to become a dominant revenue generator for manufacturers ... to reduce resource costs has led to the adoption ... and has further caused massive demand for micro irrigation ...
Breaking Medicine News(10 mins):Health News:North America Chromatography Systems Market Is Expected to Reach $6593.4 Million by 2018 - New Report by MicroMarket Monitor 2Health News:North America Chromatography Systems Market Is Expected to Reach $6593.4 Million by 2018 - New Report by MicroMarket Monitor 3Health News:Cheap Oak Caskets Recently Unveiled By China Casket Manufacturer MillionaireCasket.com 2Health News:Victorian Hotel Creates Excitement by Adding "Cycle the City" Bike Rentals for Its Vancouver Hotel Rooms 2Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 2Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 3Health News:Agricultural Micro Irrigation System Market is Expected to Grow at a CAGR of 18.1%, from 2013 to 2018 - New Report by MicroMarket Monitor 2Health News:Agricultural Micro Irrigation System Market is Expected to Grow at a CAGR of 18.1%, from 2013 to 2018 - New Report by MicroMarket Monitor 3
... , ... York, PLLC (APNY), a group of 18 established and highly regarded pediatrics practices in Queens, ... the reach of their care to extend to thousands more New York children than in ... (Vocus) March ...
... ... ... ... ...
... ... ... , , , , ... ...
... depression, PTSD, bipolar disorder in most cases, study ... -- A single-page questionnaire can help primary-care doctors ... report. , Called My Mood Monitor (M-3), the ... depression, bipolar disorder, anxiety disorders and post-traumatic stress ...
... research into how diabetics could possibly preserve their eyesight ... of children afflicted with retinoblastoma. Dolores Takemoto, a ... protein kinase C gamma in the lens of the ... when she discovered a correlation between the protein Coonexin46 ...
... Promega and ... monitoring apoptosis in live mammals, an important biomarker in cancer studies. , ... Madison, WI (PRWEB) March 9, 2010 -- Promega ... for monitoring apoptosis in live mammals, an important biomarker in cancer studies. Under the agreement, ...
Cached Medicine News:Health News:Long Island Pediatric Group Announces Policy Changes That Will Help More New Yorkers 2Health News:Long Island Pediatric Group Announces Policy Changes That Will Help More New Yorkers 3Health News:Parrish Medical Center Sees 30 Percent Improvement in Mortality Using Real-Time Clinical Surveillance Solution from Thomson Reuters 2Health News:Parrish Medical Center Sees 30 Percent Improvement in Mortality Using Real-Time Clinical Surveillance Solution from Thomson Reuters 3Health News:Parrish Medical Center Sees 30 Percent Improvement in Mortality Using Real-Time Clinical Surveillance Solution from Thomson Reuters 4Health News:Parrish Medical Center Sees 30 Percent Improvement in Mortality Using Real-Time Clinical Surveillance Solution from Thomson Reuters 5Health News:K-State Study Finds Abundance of Food Stores, Not Lack of Them, Puts Low-Income Women In Small Cities at Higher Risk of Obesity 2Health News:K-State Study Finds Abundance of Food Stores, Not Lack of Them, Puts Low-Income Women In Small Cities at Higher Risk of Obesity 3Health News:K-State Study Finds Abundance of Food Stores, Not Lack of Them, Puts Low-Income Women In Small Cities at Higher Risk of Obesity 4Health News:K-State Study Finds Abundance of Food Stores, Not Lack of Them, Puts Low-Income Women In Small Cities at Higher Risk of Obesity 5Health News:K-State Study Finds Abundance of Food Stores, Not Lack of Them, Puts Low-Income Women In Small Cities at Higher Risk of Obesity 6Health News:Survey May Help Docs Diagnose Mood Disorders 2Health News:K-State professor finds link between low oxygen levels in body and cancer-aiding protein 2Health News:Promega - TOP srl Agreement Enables Live Animal Imaging for Cancer Studies 2