Navigation Links
Transave Announces Positive Phase II Results For Once-Daily ARIKACE(TM) in the Treatment of Non-CF Bronchiectasis Patients Who Have Pseudomonas Lung Infections
Date:9/14/2009

MONMOUTH JUNCTION, N.J., Sept. 14 /PRNewswire/ -- Transave, Inc., today reported positive results from a Phase II clinical trial in non-cystic fibrosis (CF) bronchiectasis patients for its lead investigational drug, ARIKACE(TM) (liposomal amikacin for inhalation). The Phase II data indicated that ARIKACE, delivered once daily for 28 consecutive days, demonstrated superior clinical benefit compared to placebo as measured by patient and physician reported outcomes and reduction in Pseudomonas aeruginosa density. In addition, ARIKACE was well-tolerated with overall adverse events comparable to placebo. Results were presented today at the European Respiratory Society Meeting in Vienna, Austria by Anne E. O'Donnell, MD, Professor of Medicine and Chief of the Division of Pulmonary, Critical Care and Sleep Medicine, Georgetown University Hospital, and co-lead investigator of the study.

The double-blind, placebo-controlled study was designed to evaluate ARIKACE in non-CF patients who have bronchiectasis with Pseudomonas lung infections. Sixty-four adult patients were randomized to receive ARIKACE - either 280 mg or 560 mg daily dosages - or placebo. Patients received 28 days of therapy followed by a 28-day off-treatment observation period. ARIKACE and placebo were administered once daily using an eFlow (R) Nebulizer System (PARI Pharma GmbH), a novel, highly efficient, portable aerosol delivery system. Sixteen clinical sites throughout Europe and India participated in the study.

"The positive efficacy and tolerability profile demonstrated by ARIKACE in this study is encouraging for non-CF bronchiectasis patients that have pseudomonas lung infections and for physicians who treat them," said Dr. O'Donnell. "These successful results with ARIKACE are especially important since there is nothing currently approved to treat bronchiectasis patients with these types of infections."'/>"/>

SOURCE Transave, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Transave Receives $2.2 Million Cystic Fibrosis Foundation Award for Development of ARIKACE(TM)
2. Transave Announces Positive Phase II Results for Once-Daily Arikace(TM) in the Treatment of Cystic Fibrosis Patients Who Have Pseudomonas Lung Infections
3. Tobira Therapeutics Inc. Announces In Vitro Data of TBR-652 for the Treatment of HIV
4. Exsulin Corporation Announces Next Phase II Trial of Novel Islet Regeneration Treatment in Type 1 Diabetes
5. ISTA Pharmaceuticals Announces Preliminary Results of T-Pred Studies
6. BHR Pharma Announces Phase 3 SyNAPSe Study of Progesterone as a Neuroprotective Agent for Traumatic Brain Injury
7. DOR BioPharma Announces NIH Grant Award to Support Phase 1/2 Clinical Trial of DOR201 in Radiation Enteritis
8. BioSpecifics Technologies Corp. Announces XIAFLEX(TM) CORD I Study Published in New England Journal of Medicine
9. Shire Announces FDA Approval of Once-Daily INTUNIV(TM) (guanfacine) Extended Release Tablets for the Treatment of ADHD in Children and Adolescents Aged 6 to 17
10. Vion Pharmaceuticals Announces Results of the Oncologic Drugs Advisory Committee Meeting for Onrigin(TM)
11. Sagent Pharmaceuticals Announces Launch of Adenosine Injection, USP, in 6 mg per 2 mL Single-Dose Vials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... Electrophysiologist Kevin Makati, M.D. with St. ... Boston, MA to speak about ... Society conference. These scientific sessions drew more than ... people and technology that propel their specialty forward. ... invasive cardiac operation that combines the expertise of ...
(Date:5/22/2015)... , May 22, 2015  RegeneRx Biopharmaceuticals, Inc. (OTCQB: ... protection, repair and regeneration, today announced that J.J. ... to present a corporate overview at two upcoming investor ... the SeeThruEquity 4 th Annual Microcap Conference on ... City at 11:00 am EDT.  A webcast ...
(Date:5/22/2015)... ROCKVILLE, Md. , May 22, 2015 /PRNewswire/ ... "RegeneRx") today announced a peer-reviewed publication of the ... study evaluating RGN-259 (RegeneRx,s preservative-free eye drops) for ... Inc.,s controlled adverse environment (CAE ® ) model.  ... and the results, which were previously disseminated by ...
Breaking Medicine Technology:St. Joseph's Hospital Heart Institute Physician Presents at Heart Rhythm Society 2St. Joseph's Hospital Heart Institute Physician Presents at Heart Rhythm Society 3RegeneRx to Present at 2 Investor Conferences 2RegeneRx to Present at 2 Investor Conferences 3Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 2Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 3Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 4
(Date:5/25/2015)... (PRWEB) May 25, 2015 Decora Preset ... ‘Leviton’ is now available on ‘The Hardware City.’ The product ... has to set a time and the related electronic device ... contacted a representative of the company said, “We are glad ... City.’ Now customers can buy Countdown Timer Switch in just ...
(Date:5/24/2015)... 24, 2015 Women’s Excellence ... pressure measurements in patients’ bladder and urethra. This provides ... it if they have reported symptoms of stress urinary ... Women’s Excellence in Bladder Control is a comprehensive center ... or problems with overall control of their bladder. The ...
(Date:5/24/2015)... 24, 2015 Indiana Fiber Network, LLC ... Midwest Telecom of America, Inc. (MTA) has selected IFN ... Cory Childs, IFN Enterprise Sales Manager, fiber route diversity ... “IFN’s fiber transport provides MTA with the diverse fiber ... Tier 1 Internet and voice carriers located at Henry ...
(Date:5/23/2015)... Washington, D.C. (PRWEB) May 23, 2015 ... demonstration of powers of a youngster's yogic power learned ... by Sri Nithyananda Swami in Bangalore, India. , Yogamaatha, ... of more than 50 high profile professionals attending the ... D.C. by reading fluently -- blindfolded. , In ...
(Date:5/23/2015)... 2015 Manufacturers are now required to produce ... of 8.2. Experts in the field agree that the regulation ... The HSPF score is what miles per gallon is to ... unit. Although the minimum HSPF score has been raised to ... HSPF score north of 12. Indeed, the regulation was welcomed ...
Breaking Medicine News(10 mins):Health News:Leviton's Decora 60 Minute Countdown Timer Available On ‘The Hardware City’ 2Health News:Indiana Fiber Network, LLC Enables Midwest Telecom of America with Fiber Route Diversity 2Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 2Health News:Nine-Year-Old Reads Blindfolded at Business Advocacy Summit 3Health News:Parker & Sons Welcomes the Department of Energy’s Water Heater Regulation 2
... prior team, DELRAY BEACH, Fla., Sept. 9 ... important addition to,its board of directors. Mr. Geary Cotton ... two persons that Mr. Carl DeSantis has the right ... CDS Ventures of South,Florida, LLC. Mr. Cotton has 15 ...
... know that sugar,makes good foods taste better, helps breads ... of jams and jellies. But,did you know the same ... help heal wounds?, Sugar is one of Mother ... make sugar an excellent food preservative also bestow,it with ...
... 9 Focus 28, Inc. announced today,that it ... generation line of,meal replacements and nutritional supplements designed ... According to the company,Bariatric RX not only features ... Double A Technology (AAT), a unique nutritional,delivery system., ...
... Researchers from the University of Pennsylvania School of Medicine ... and suppression of esophageal cancers and perhaps carcinomas ... tissue samples, they found that Fbx4, a naturally occurring ... another protein called Cyclin D1, which is thought to ...
... Findings urge push for broad-based admission policies that reflect ... Attending medical schools with high levels of racial and ... care for minority patients, U.S. researchers say. , The ... graduating medical students from 118 medical schools. It found ...
... 9 Governor Edward G.,Rendell today announced the ... as Secretary of the Pennsylvania Department of Health ... passionate voice for protecting and improving,the health of ... as an effective leader, addressing a variety of,issues ...
Cached Medicine News:Health News:Celsius Strengthens Board With Prior Rexall Sundown CFO 2Health News:Sugar's Healing Powers 2Health News:Focus 28 Begins Shipping Next Generation Line of Meal Replacements and Food Supplements for Bariatric Patients 2Health News:Penn researchers identify natural tumor suppressor 2Health News:Med School Diversity May Help Whites Care Better for Minorities 2Health News:Med School Diversity May Help Whites Care Better for Minorities 3Health News:Governor Rendell Announces Resignation of Health Secretary Dr. Calvin Johnson 2
For the qualitative detection of antibodies to HIV-1 and HIV-2 in human serum, plasma and whole blood specimens...
For the qualitative detection of antibodies to HIV-1 and HIV-2 in human serum, plasma and whole blood specimens...
For the qualitative detection of antibodies to HIV-1 and HIV-2 in human serum, plasma and whole blood specimens...
... insulin pen with a memory. HumaPen MEMOIR records the ... (including priming doses). You can see exactly when and ... you simply "dial" your dose by turning the dose ... initial set-up. If you dial too many units, you ...
Medicine Products: