Navigation Links
Transave Announces Positive Phase II Results For Once-Daily ARIKACE(TM) in the Treatment of Non-CF Bronchiectasis Patients Who Have Pseudomonas Lung Infections
Date:9/14/2009

MONMOUTH JUNCTION, N.J., Sept. 14 /PRNewswire/ -- Transave, Inc., today reported positive results from a Phase II clinical trial in non-cystic fibrosis (CF) bronchiectasis patients for its lead investigational drug, ARIKACE(TM) (liposomal amikacin for inhalation). The Phase II data indicated that ARIKACE, delivered once daily for 28 consecutive days, demonstrated superior clinical benefit compared to placebo as measured by patient and physician reported outcomes and reduction in Pseudomonas aeruginosa density. In addition, ARIKACE was well-tolerated with overall adverse events comparable to placebo. Results were presented today at the European Respiratory Society Meeting in Vienna, Austria by Anne E. O'Donnell, MD, Professor of Medicine and Chief of the Division of Pulmonary, Critical Care and Sleep Medicine, Georgetown University Hospital, and co-lead investigator of the study.

The double-blind, placebo-controlled study was designed to evaluate ARIKACE in non-CF patients who have bronchiectasis with Pseudomonas lung infections. Sixty-four adult patients were randomized to receive ARIKACE - either 280 mg or 560 mg daily dosages - or placebo. Patients received 28 days of therapy followed by a 28-day off-treatment observation period. ARIKACE and placebo were administered once daily using an eFlow (R) Nebulizer System (PARI Pharma GmbH), a novel, highly efficient, portable aerosol delivery system. Sixteen clinical sites throughout Europe and India participated in the study.

"The positive efficacy and tolerability profile demonstrated by ARIKACE in this study is encouraging for non-CF bronchiectasis patients that have pseudomonas lung infections and for physicians who treat them," said Dr. O'Donnell. "These successful results with ARIKACE are especially important since there is nothing currently approved to treat bronchiectasis patients with these types of infections."'/>"/>

SOURCE Transave, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Transave Receives $2.2 Million Cystic Fibrosis Foundation Award for Development of ARIKACE(TM)
2. Transave Announces Positive Phase II Results for Once-Daily Arikace(TM) in the Treatment of Cystic Fibrosis Patients Who Have Pseudomonas Lung Infections
3. Tobira Therapeutics Inc. Announces In Vitro Data of TBR-652 for the Treatment of HIV
4. Exsulin Corporation Announces Next Phase II Trial of Novel Islet Regeneration Treatment in Type 1 Diabetes
5. ISTA Pharmaceuticals Announces Preliminary Results of T-Pred Studies
6. BHR Pharma Announces Phase 3 SyNAPSe Study of Progesterone as a Neuroprotective Agent for Traumatic Brain Injury
7. DOR BioPharma Announces NIH Grant Award to Support Phase 1/2 Clinical Trial of DOR201 in Radiation Enteritis
8. BioSpecifics Technologies Corp. Announces XIAFLEX(TM) CORD I Study Published in New England Journal of Medicine
9. Shire Announces FDA Approval of Once-Daily INTUNIV(TM) (guanfacine) Extended Release Tablets for the Treatment of ADHD in Children and Adolescents Aged 6 to 17
10. Vion Pharmaceuticals Announces Results of the Oncologic Drugs Advisory Committee Meeting for Onrigin(TM)
11. Sagent Pharmaceuticals Announces Launch of Adenosine Injection, USP, in 6 mg per 2 mL Single-Dose Vials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... , Nov. 26, 2014  Avanir Pharmaceuticals, ... the U.S. Food and Drug Administration (FDA) has ... Drug Application (NDA) for AVP-825. AVP-825 is an ... powder delivered intranasally utilizing a novel Breath Powered ... Response letter, and consistent with the preliminary feedback ...
(Date:11/26/2014)... -- BioScrip ® , Inc. (NASDAQ: BIOS ) announced today ... will present at the Bank of America Merrill Lynch 2014 Leveraged ... , , , Wednesday, December 3, 2014 , , , ... , , Location: , , , Boca Raton Resort and Club, ... BioScrip, Inc. is a leading national provider of ...
(Date:11/26/2014)... 26, 2014  Aridis Pharmaceuticals, Inc., a biopharmaceutical ... for infectious diseases, announced today the addition of ... key opinion leader in the areas of pneumonia ... Founder and Chief Executive Officer, ... Opal,s extensive experience investigating bacterial toxins and key ...
Breaking Medicine Technology:Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 2Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 3Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 4Aridis Pharmaceuticals Appoints Dr. Steven Opal to Scientific Advisory Board 2Aridis Pharmaceuticals Appoints Dr. Steven Opal to Scientific Advisory Board 3
(Date:11/28/2014)... 29, 2014 The report “Poxvirus ... on the therapeutic development for Poxvirus Infections, complete ... by drug target, mechanism of action (MoA), route ... latest updates, and featured news and press releases. ... therapeutic development for Poxvirus Infections and special features ...
(Date:11/28/2014)... Recently, PrettyTailor.com has developed and created its ... around the world in celebration of the coming holiday ... launched a special offer on all these outfits. ... pioneer in the garment industry, PrettyTailor.com brings together art ... and small. The business carries quite a few in ...
(Date:11/28/2014)... The holiday season is fast approaching. As a ... collection of fashionable party dresses. What’s more, the company is ... brand new outfits; the special offer is valid until Dec. ... supplier and it has received a lot of requests for ... designed to flatter various body shapes; they are available in ...
(Date:11/28/2014)... York, NY (PRWEB) November 28, 2014 ... Salvage ( http://www.rustysautosalvage.com ), one of the nation's leading ... junk and salvage vehicles to be more competitive and ... customer’s lives during this festive time of year. , ... many car owners across the US also deal with ...
(Date:11/28/2014)... York (PRWEB) November 28, 2014 ... to move forward in New Jersey’s Bergen County ... a consolidated litigation established there is quickly approaching ... updated on November 18th shows 1,293 lawsuits now ... for lawsuits that allege complications resulting from spontaneous ...
Breaking Medicine News(10 mins):Health News:Poxvirus Infections and Vestibular Diseases Pipeline Market Drugs and Companies Review H2 2014 2Health News:Poxvirus Infections and Vestibular Diseases Pipeline Market Drugs and Companies Review H2 2014 3Health News:Poxvirus Infections and Vestibular Diseases Pipeline Market Drugs and Companies Review H2 2014 4Health News:2015 Wedding Dresses from PrettyTailor.com Available Now 2Health News:Trendy Party Dresses For The Coming Holiday Season From Balfleet.com 2Health News:Rusty's Auto Salvage Increasing Their Cash Offers to Help Drivers Save Throughout the Busy Holiday Season 2Health News:Nearly 1,300 Mirena Lawsuits Now Filed in Consolidated New Jersey Litigation, Bernstein Liebhard LLP Reports 2Health News:Nearly 1,300 Mirena Lawsuits Now Filed in Consolidated New Jersey Litigation, Bernstein Liebhard LLP Reports 3
... site, Best Branded ... WEST CONSHOHOCKEN, Pa., March 10 Cadient Group, ... today it has received multiple nominations for the 2008,DTC ... the DTC,National Advertising Awards Dinner on April 17, 2008., ...
... 8 a.m. EDT, SHENZHEN, China, March 10 /Xinhua-PRNewswire-FirstCall/ ... ("Nepstar" or "the Company"), the,largest drugstore chain in China ... that it will report financial results for the,fourth quarter ... market,opens on March 19, 2008., The Company will ...
... and SUZHOU, China, March 10 ,Wyeth (NYSE: ... $280 million to,build a state-of-the-art nutritional manufacturing facility ... facility will primarily,produce infant formula milk powder and ... one of the world,s largest nutritional,manufacturing facilities., ...
... Conn., March 10 Therap Services announces,the appointment ... Services is a web-based service bureau offering an ... Therap has a,customer support team consisting of former ... "We are happy to have Anna in ...
... Scientists funded by the Biotechnology and Biological Sciences ... the journal Molecular Pharmacology identifying the structure of ... such as epilepsy and pre-menstrual tension. The same ... sensitive to alcohol. , The University of Cambridge ...
... after breathing, stretching program still evident 3 months ... -- Yoga helps ease hot flashes and other menopausal ... , Some of the 37 women who,d had early ... of Awareness" program, while others were assigned to a ...
Cached Medicine News:Health News:Cadient Group Receives Multiple Nominations for 2008 DTC National Advertising Awards 2Health News:China Nepstar Chain Drugstore to Announce Fourth Quarter 2007 Financial Results on March 19 2Health News:China Nepstar Chain Drugstore to Announce Fourth Quarter 2007 Financial Results on March 19 3Health News:Wyeth to Invest $280 Million to Build State-of-the-Art Nutritional Manufacturing Facility in China 2Health News:Wyeth to Invest $280 Million to Build State-of-the-Art Nutritional Manufacturing Facility in China 3Health News:Therap Services Welcomes Anna Keith to the US Customer Support Team 2Health News:Scientists determine structure of brain receptor implicated in epilepsy and PMT 2Health News:Yoga Eases Menopause Symptoms in Breast Cancer Survivors 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: