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TransGenRx Protein Therapeutics Technology to Support Research Related to Protein-Based HDL Therapies at Esperion Therapeutics
Date:6/21/2010

PLYMOUTH, Mich. and BATON ROUGE, La., June 21 /PRNewswire/ -- Esperion Therapeutics, a privately held biopharmaceutical company working to discover, develop and commercialize treatments for cardiovascular and metabolic diseases, today announced that TransGenRx, a global leader in transgenic technology, will produce protein-based therapeutics to be used in the company's research efforts targeting HDL therapies for the treatment of cardio-metabolic disease. Under the terms of the agreement, TransGenRx will coordinate production of protein-based therapies for a range of research needs using a proprietary expression system.

Researchers at Esperion are working to develop novel therapies to treat cardio-metabolic disease including therapies based on HDL, the body's "good" cholesterol, which has been shown to play an important role in lipid management. The company's development platform includes therapies designed to mimic or enhance the function of HDL in managing and removing cholesterol and other lipids from atherosclerotic plaques. Researchers at Esperion have initiated preclinical and clinical research related to a variety of pathways for better lipid regulation to treat the full spectrum of cardio-metabolic diseases, from early risk factors to acute coronary syndromes and atherosclerosis.

"While HDL continues to show great promise in the treatment of cardiovascular disease, there have been significant challenges in the development of protein-based drug therapies. By working with the outstanding research and technology team at TransGenRx, we are positioned to access one of the most advanced, cost-effective protein expression technologies in the world to supply the protein-based therapies we will use in our research," said Roger Newton, Ph.D., President and CEO of
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SOURCE Esperion Therapeutics, Inc.
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