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Trana Discovery and Southern Research Institute Find Bioactive HIV Antiviral Compounds
Date:10/28/2009

dy the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. The NIAID is a component of the National Institutes of Health (NIH), the primary federal agency for conducting and supporting basic, clinical and translational medical research. Work for this project was performed under the DAIDS, NIAID contract N01-AI-70042; Roger Miller, Project Officer.

The HTS screening was conducted at the Southern Research High-Throughput Screening Center which consists of a suite of laboratories designed for efficient screening of large compound libraries and has the capacity for screening a wide variety of assay types. The Trana Discovery assay was recently validated in a 1536 well format, which increases the screening capabilities to over 100,000 compounds per day.

Organizations interested in licensing the Trana HIV 201 assay should contact Trana at info@tranadiscovery.com or by calling 866-390-3452 (toll free) or +1-919-342-6192. Parties interested in screening compounds using this assay at Southern Research Institute facilities may contact David Harris at d.harris@southernresearch.org or call +1-800-967-6774.

About Trana Discovery, Inc.

Trana Discovery, an anti-infective drug discovery technology company, helps its partners find new classes of drugs for the treatment of serious bacterial, viral, and fungal infectious diseases. Our proprietary assays identify compounds that work through a unique mechanism of action: inhibition of the target pathogen's ability to use transfer RNA (tRNA) essential for propagation. The use of high-throughput screening assays developed by Trana Discovery will reduce the cost and time for drug discovery. Our assays provide licensing opportunities for exclusive rights to ne
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SOURCE Southern Research Institute
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