Navigation Links
Trana Discovery and Southern Research Institute Announce the First RNA-RNA High Throughput Drug Screening Assay Platform for HIV Antivirals
Date:9/17/2007

this novel mechanism of action.

At the state-of-the-art High Throughput Screening Center at Southern Research, the Trana Discovery RNA assay was adapted to the robotics platform. By using precision robotics, highly accurate low volume liquid handling devices, sensitive detectors and powerful data processing software, the HTS assay that was developed will allow researchers to quickly conduct millions of tests that identify active compounds. The data generated from a large screen like this provides the starting point for drug design and development. Using this newly validated assay, the HTS Center at Southern Research can screen 50,000 compounds per day.

"We consider the HIV HTS assay as a major breakthrough in the development of new techniques in the early-stage drug discovery and development process," said David Harris, director of Drug Discovery Business Development at Southern Research. "The addition of the tRNA assay platform adds to our service offerings that lead to the improvement of people's lives around the world."

Trana Discovery and Southern Research are currently developing other HTS assays to identity compounds that interrupt the lifecycle of bacteria, such as E.coli and Methicillin-resistant Staphylococcus aureus (MRSA).

"The development of the HTS assay validates that our technology can be adapted to the automated platforms used for high throughput screening, and signals a major step forward in its advancement," said Steve Peterson, CEO of Trana Discovery. The patented technology has been under extensive development at North Carolina State University. "We are now ready for the commercialization and licensing of this technology to discover new classes of compounds that will inhibit HIV via a unique mechanism of action," said Peterson.

Trana Discovery is seeking diverse collections of compounds or compounds with known bioactivity against HIV but unknown mechanism of action to identify candidates for drug development. Organiz
'/>"/>

SOURCE Southern Research Institute
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Bentley Reports Positive Results with Nasulin Intranasal Insulin Spray at the American Diabetes Association Meeting
2. Trial Results with Intranasal Fentanyl Hold Promise for Treatment of Breakthrough Pain in Cancer
3. Roxro Pharma’s Novel Intranasal Pain Reliever Effective, Well Tolerated in Phase 3 Study
4. Javelin Pharmaceuticals Phase II Rylomine (Intranasal Morphine) Data Published in Pain Medicine
5. Daytrana (methylphenidate transdermal system) Provides Significant Effectiveness in ADHD Symptom Relief in Both Boys and Girls
6. 12-Month Study Demonstrated Tolerability and Efficacy of DAYTRANA (methylphenidate transdermal system)
7. Major New Review Supports the Broader Potential of CeNeS COMT Inhibitor Discovery Programme
8. Discoverys KL-4 Surfactant Technology Demonstrates Novel Anti-Inflammatory Properties
9. Discovery Labs Presents Surfaxin and Aerosurf Data At the Pediatric Academic Societies Annual Meeting
10. Major Discovery Raises Prospect of Better Patient Care By Improving Platelet Life Span
11. Southern Research Institute to Present at the 2007 American Association For Cancer Research Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... DIEGO , Dec. 23, 2014 ResMed (NYSE: ... significant patent infringement action against Chinese medical device manufacturer BMC ... (ITC) ruled today that BMC,s masks listed below infringe ResMed,s ... or selling these masks in the United States ... iVolve N2 nasal mask , Willow nasal pillows mask ...
(Date:12/24/2014)... ALEXANDRIA, Va. , Dec. 23, 2014 /PRNewswire-USNewswire/ ... stringent diastolic blood pressure target for people with ... either moderate or high doses of statins, in ... risk management enacted by the American College of ... recommendations are reflected in the most recent changes ...
(Date:12/22/2014)... , Dec. 22, 2014  CytoSorbents Corporation ... its CytoSorb® blood purification technology to help fight ... in 28 countries worldwide, today announced the appointment ... MD, FACS, as its Senior Vice President of ... Dr. Di Russo is an ...
Breaking Medicine Technology:ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 2New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 3New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5
... Depomed, Inc. (NASDAQ: DEPO ) today ... payment from Ironwood Pharmaceuticals, Inc. following the development and ... candidate meeting pre-specified attributes under its Research Collaboration and ... in July 2011. Under the terms of the agreement, Depomed ...
... China, May 11, 2012 /PRNewswire-Asia/ -- Simcere Pharmaceutical Group ... a leading pharmaceutical company specializing in the development, manufacturing, ... today announced that the annual general meeting of shareholders ... 2012 at 10 a.m. Beijing time. The meeting will ...
Cached Medicine Technology:Depomed Announces Receipt of $1 million Milestone Payment From Ironwood Pharmaceuticals, Inc. 2Simcere Pharmaceutical Group Provides Notice of Annual General Meeting 2
(Date:12/25/2014)... This is a professional and in-depth ... industry with a focus on the Chinese market. The ... the Sterilizers manufacturers and is a valuable source of ... the industry. This report provides a basic overview of ... In this part, the report presents the company profile, ...
(Date:12/25/2014)... York (PRWEB) December 25, 2014 Product ... DePuy ASR hip recall ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to ... According to an Order issued in the U.S. District ... Court will convene an open conference on January 7, ... United States Courthouse in West Palm Beach, Florida. The ...
(Date:12/25/2014)... The short film “Color of Honor” by ... of a true 9/11 hero, Welles Remy Crowther. It has ... 24 hours of Nuremberg International Short Film Festival and the ... Actress, screenwriter and director Luciana Lagana plays the mother ... her husband, Gregory Graham - Graham plays a ...
(Date:12/25/2014)... FL (PRWEB) December 25, 2014 When head ... find themselves in a frenzy to get rid of it ... But families in Coral Gables now have the solution right ... second salon clinic location, Lice Troopers provides full spectrum head ... the Coral Gable area, including Sunset, Key Biscayne, Brickell, Coconut ...
(Date:12/25/2014)... 2014 (HealthDay News) -- Overeating is common during the holidays, ... moderation, an expert says. "Don,t arrive at a party ... you know you,ll be attending a party, but deprivation leads ... dietitian at Northern Westchester Hospital in Mount Kisco, N.Y., said ... healthy during the day and even to have a snack ...
Breaking Medicine News(10 mins):Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 3Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2
... potential therapeutic value in children with respiratory disorders for ... of difficulty breathing and for lessening a child,s discomfort ... adjunct to conventional treatment and its ability to use ... explored in a provocative paper in Pediatric Asthma, ...
... in humans, research shows , FRIDAY, Feb. 12 (HealthDay News) -- ... on the balls of your feet or on your toes, a ... 83 percent more energy to walk on your toes and 53 ... according to the University of Utah researchers. They measured energy expenditure ...
... ... signature solution, to present the use of digital signatures in clinical trial management applications ... ... February 12, 2010 -- ARX, the leading provider of digital signature solutions, will be ...
... , MIAMI , ...  With everything in place for a passionate Valentine,s Day ... fumble before the tumble spoil the perfect evening.  Sensis makes applying ... partners. , "Our number one goal is to help people ...
... May Be Alternative to Allergy Shots , PITTSBURGH , ... under the tongue is a safe and effective alternative to injections ... study published today in the Journal of Allergy and Clinical Immunology ... used in Europe , but not yet approved by the ...
... of suffering a stroke are linked to the presence of ... new study from Karolinska Institutet shows. The researchers hope to ... body,s own defence against arteriosclerosis and stroke. The ... previously demonstrated that high levels of a certain type of ...
Cached Medicine News:Health News:Hypnosis can relieve symptoms in children with respiratory diseases 2Health News:Heel-First Walking Conserves Energy 2Health News:Digital Signatures Presented at Electronic Document Management Conference 2Health News:Sensis Condoms With QuikStrips(TM) Reminds Lovers To Protect The Passion This Valentine's Day 2Health News:Sensis Condoms With QuikStrips(TM) Reminds Lovers To Protect The Passion This Valentine's Day 3Health News:Allegheny General Hospital Study Demonstrates Safety and Potential Efficacy of Oral Allergy Treatment 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: