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Traitement du cancer primaire du foie : l'étude SARAH désormais accessible aux patients concernés sur l'ensemble du territoire français
Date:6/20/2013

aussi appelée radioembolisation, est une thérapie innovante des cancers hépatiques inopérables permettant de délivrer de très fortes doses de radiation directement aux tumeurs, tout en épargnant les tissus sains. C'est un traitement peu invasif qui consiste à injecter, via un cathéter, des millions de microsphères SIR-Spheres radioactives (diamètre compris entre 20 et 60 microns) dans les artères hépatiques afin de cibler directement la/les tumeur(s) avec une dose d'irradiation interne jusqu'à 40 fois plus importante qu'avec une radiothérapie conventionnelle.

Références :

  1. SorAfenib versus Radioembolization in Advanced Hepatocellular carcinoma (SARAH): http://clinicaltrials.gov/ct2/show/NCT01482442.
  2. Sangro B, Carpanese L, Cianni R et al on behalf of European Network on Radioembolization with yttrium-90 resin microspheres (ENRY). Survival after 90Y resin microsphere radioembolization of hepatocellular carcinoma across BCLC stages: A European evaluation. Hepatology 2011; 54: 868-878.
  3. GLOBOCAN. Liver Cancer Incidence and Mortality Worldwide in 2008. http://globocan.iarc.fr/factsheets/cancers/liver.asp accessed 28 June 2011.


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SOURCE SARAH trialists
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