Navigation Links
Tracleer(R) Shows Clinical Benefit as Combination Therapy with Sildenafil for Pulmonary Arterial Hypertension
Date:10/23/2007

stage PAH patients as a monotherapy.

About Tracleer(R) in Pulmonary Arterial Hypertension (PAH)

Tracleer(R) (bosentan), the first oral dual endothelin receptor antagonist, is approved for the treatment of pulmonary arterial hypertension (PAH) and made available by Actelion Ltd. subsidiaries in the United States, the European Union, Japan, Australia, Canada, Switzerland and other markets worldwide.

Tracleer requires attention to two significant safety concerns: potential for serious liver injury (including rare cases of liver failure and unexplained hepatic cirrhosis in a setting of close monitoring) and high potential for major birth defects. Liver monitoring of all patients is essential prior to initiation of treatment and monthly thereafter. Pregnancy must be excluded and prevented by two forms of birth control; monthly pregnancy tests should be obtained. Because of these risks, Tracleer is only supplied through a controlled distribution system.

About Actelion Pharmaceuticals

Actelion Pharmaceuticals has pioneered research and development in the pulmonary arterial hypertension (PAH) disease area. More than 40,000 PAH patients have been prescribed Actelion's product Tracleer(R) (bosentan), an orally available dual endothelin receptor antagonist for patients with World Health Organization (WHO) Class III or IV PAH in the U.S., and Class III PAH in Europe. Tracleer was approved in 2001 as the first oral treatment for PAH, and is currently approved in the U.S., the European Union, and other markets worldwide. In January 2007, Actelion acquired CoTherix, Inc., whose product Ventavis(R) (iloprost) Inhalation Solution is approved and marketed in the United States for the treatment of patients with WHO Class III or IV PAH.


'/>"/>
SOURCE Actelion Pharmaceuticals US, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Clinical Study Shows Regenecare Relieves Pain and Itching of Skin Rashes Caused by Widely Used Cancer Drugs
2. International ENDORSE Study Shows That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE prophylaxis
3. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
4. MediGene Announces Cancer-Fighting Virus Shows Promise in Early Clinical Trial
5. Study Shows Ixabepilone Demonstrated Clear Activity in Patients with Metastatic Breast Cancer Resistant to Anthracycline, Taxane, and Capecitabine
6. Ceragenix Compound Shows Promise for Treating Lethal Cystic Fibrosis Infections
7. Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types
8. CombinatoRx Product Candidate CRx-150 Shows Activity on DAS28 and Pain, but Not CRP
9. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
10. First Phase II Short-Term Study on Dapagliflozin Shows Results on Safety, Tolerability and Glycemic Markers in Subjects With Type 2 Diabetes
11. New Poll Shows Men, Women Incorrectly Blame Symptoms of Low Testosterone on Normal Aging
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)...  Hill-Rom Holdings, Inc. (NYSE: HRC ) ... the Morgan Stanley Global Healthcare Conference on September 8, ... invited to listen to the live discussion via the ... directly at http://cc.talkpoint.com/morg007/090814a_ac/?entity=26_7CLOGQP .  A recorded replay of ... of the live event and accessible at the links ...
(Date:8/27/2014)... , Aug. 27, 2014 North American lighting ... prestigious R&D 100 Award for the new OSRAM ITOS ® ... LED-based white light module for microscopy, endoscopy and surgical head ... with significantly higher efficacy and lamp life. "We,re ... one of the most innovative new technologies of the past ...
(Date:8/27/2014)... , Aug. 27, 2014 Amgen (NASDAQ: ... Drug Administration (FDA) has granted priority review designation for ... Ivabradine is an oral drug that inhibits the ... sinoatrial node, the body,s cardiac pacemaker. 1 Ivabradine ... on myocardial contractility or ventricular repolarization. 1 Heart ...
Breaking Medicine Technology:OSRAM ITOS PHASER 3000 Laser and LED Light Module Recognized With Prestigious R&D 100 Award 2OSRAM ITOS PHASER 3000 Laser and LED Light Module Recognized With Prestigious R&D 100 Award 3FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 2FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 3FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 4FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 5FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 6FDA Grants Amgen Priority Review Designation For Ivabradine For The Treatment Of Chronic Heart Failure 7
... 2011 Omthera Pharmaceuticals, Inc., a privately-held emerging ... President and Chief Executive Officer, will present at ... the Westin St. Francis Hotel in San Francisco, ... PT. About Omthera Pharmaceuticals, Inc.Founded ...
... Medical Technologies, Inc. today announced that Allina Hospitals ... company,s integrated electronic health record (EHR) practice management ... across Minnesota and western Wisconsin. ... ability to interface tightly with Allina,s Epic-based electronic ...
Cached Medicine Technology:Greenway's PrimeSUITE Endorsed by Allina Hospitals & Clinics 2Greenway's PrimeSUITE Endorsed by Allina Hospitals & Clinics 3
(Date:8/28/2014)... MarijuanaDoctors.com is enthralled to announce the addition ... Livermore, California. As always, MarijuanaDoctors.com prides itself on affiliating ... in accordance with that, we are excited to introduce ... , Initially finding his calling for healing and interest ... shaped by his mother’s severe arthritis to finally become ...
(Date:8/28/2014)... Texas (PRWEB) August 28, 2014 The need ... growth over the past few years. The new location - ... offer higher quality and larger office space than TLC had ... , “We are pleased about our new location because ... “While our suite will be double in size compared to ...
(Date:8/27/2014)... Villanova, PA (PRWEB) August 28, 2014 ... (published by iUniverse) takes readers on the thrilling adventures ... The book, published in 2012, is gearing up for ... 2014. , Split into two novellas , “Prescription: ... orthopedic surgeon who finds himself dodging assassination attempts and ...
(Date:8/27/2014)... Recently, BambooIndustry.com, an innovative company that provides many kinds of ... panels are now offered on its website. In addition, ... All people that place an order for its newly released ... percent off. , The company’s senior spokesman was excited ... our new and old customers can buy cheap bamboo panels ...
(Date:8/27/2014)... National Resident Matching Program International ... Medical Education in Europe (AMEE) Conference being held at ... – September 3, 2014. As an exhibitor, NRMPI ... community, share the benefits of its matching services, and ... in countries throughout the world. , “Exhibiting ...
Breaking Medicine News(10 mins):Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 2Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 3Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 4Health News:William H. Simon Launches New Marketing Campaign for Book 2Health News:BambooIndustry.com: Cheap Bamboo Panels for Clients Worldwide Offered Online 2Health News:National Resident Matching Program International (NRMPI) to Exhibit at the 2014 AMEE Conference 2
... 23 James. G. Schwade, M.D. announces the newly enhanced CyberKnife ... ( www.cyberknifemiami.com ). , The CyberKnife treatment for cancer ... cells with no invasive surgical incision. The length of the ... usually completed in 1- 5 treatments. , As the ...
... 20 percent get infected within one year of starting to ... News) -- As many as one in four U.S. teenage ... soon after their first sexual encounter, a new government report ... reminds us that we can,t ignore this," said study author ...
... is leading an initiative that could result in a paradigm ... Morehouse University School of Medicine and University of ... care physicians across Georgia to serve as "medical homes" for ... sends them to the hospital and seeking better prevention and ...
... , ... Instacare Corp. (OTC Bulletin Board: ISCR) announced today that its ... e-health technologies have been successfully engineered to seamlessly function on ... hand-held interactive medical software to the Apple iPhone, the Palm ...
... , NEW ORLEANS, Nov. 23 Thanksgiving weekend marks the 36th annual ... the sportsmanship and pride of two schools but it is so much ... in attendance. , For the crew of the new U.S. Coast Guard ... before they work to test and launch a brand new ship to ...
... ... and Automate Billing, Claims, Enrollment and Eligibility, , ... (PRWEB) November 23, 2009 -- BridgeGate ... the launch of new products within its healthcare integration suite, designed to help ...
Cached Medicine News:Health News:One in Four Teen Girls Have STDs 2Health News:One in Four Teen Girls Have STDs 3Health News:Initiative could result in paradigm shift in the care of sickle cell patients 2Health News:Initiative could result in paradigm shift in the care of sickle cell patients 3Health News:Initiative could result in paradigm shift in the care of sickle cell patients 4Health News:Initiative could result in paradigm shift in the care of sickle cell patients 5Health News:ISCR Becomes Instant Player in the Obamacare EMR/Cost Savings Sweepstakes 2Health News:ISCR Becomes Instant Player in the Obamacare EMR/Cost Savings Sweepstakes 3Health News:Nothing Is Like Being There 2Health News:BridgeGate Launches New Healthcare Integration and Interoperability Products 2Health News:BridgeGate Launches New Healthcare Integration and Interoperability Products 3Health News:BridgeGate Launches New Healthcare Integration and Interoperability Products 4
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: