Navigation Links
Topaz Pharmaceuticals' Ivermectin Cream In Vitro Data Demonstrates Activity Against Head Lice Eggs
Date:7/11/2011

HORSHAM, Pa., July 11, 2011 /PRNewswire/ -- In a study sponsored by Topaz Pharmaceuticals Inc., a privately held specialty pharmaceutical company, scientists from the University of Massachusetts, Amherst presented data showing that a 0.5% ivermectin (IVM) cream formulation was active against lice eggs from permethrin resistant head lice.  The data were presented in a poster presentation on Saturday, July 9, 2011 at the 37th Annual Meeting of the Society for Pediatric Dermatology in Baltimore, Maryland.  

"These data build on our earlier work showing this ivermectin formulation is active against head lice," said John M. Clark, Ph.D., Professor of Veterinary and Animal Sciences, University of Massachusetts Amherst.  "The data suggest that a single treatment with 0.5% ivermectin cream has the potential to fully break the head louse life cycle.   If approved by the FDA, ivermectin cream has the potential to provide physicians with an attractive treatment option."  

In the study, permethrin resistant head lice were allowed to lay eggs in tufts of human hair.  Adult lice were removed and the tufts with eggs were exposed to 0.5% ivermectin cream, to vehicle only, or to unformulated, diluted ivermectin. After a 10-minute exposure, tufts were thoroughly rinsed and incubated.  Any hatched lice were placed onto new tufts and moved to a feeding cup.  The hatchability of treated eggs was not affected by ivermectin. No differences were detected between the mortality rate of eggs exposed to 0.5% ivermectin cream and those exposed to unformulated ivermectin.  The percent of hatched lice from eggs exposed to 0.5% ivermectin cream that took a blood meal, relative to eggs exposed to placebo, was significantly decreased (by 82-95%).  All hatched lice from eggs treated with 0.5% ivermectin cream died within 48 hours.  

About Ivermectin
'/>"/>

SOURCE Topaz Pharmaceuticals Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Topaz Pharmaceuticals Announces New Drug Application for the Treatment of Head Lice Accepted by FDA
2. Topaz Pharmaceuticals Names Dr. Mark Strobeck Chief Business Officer
3. Topaz Pharmaceuticals Announces Completion of Pivotal Phase 3 Trials of Ivermectin Topical Cream
4. Topaz Pharmaceuticals Names Bob Radie Chief Executive Officer
5. TOPAZ Technologies and ML Weekes & Company Announce Partnership
6. Shareholder Class Action Filed Against SciClone Pharmaceuticals, Inc. by the Law Firm of Barroway Topaz Kessler Meltzer & Check, LLP
7. Topaz Pharmaceuticals Announces Positive Data from Topical Ivermectin Trials Presented at Society of Pediatric Dermatology
8. TOPAZ Technologies and Tecniplast USA Launch RFID Mobile Census
9. Shareholder Class Action Filed Against Rigel Pharmaceuticals, Inc. by the Law Firm of Barroway Topaz Kessler Meltzer & Check, LLP
10. Shareholder Class Action Filed Against Vertex Pharmaceuticals Incorporated by the Law Firm of Schiffrin Barroway Topaz & Kessler, LLP
11. Schiffrin Barroway Topaz & Kessler, LLP and Janet Jenner & Suggs, LLC Comment on Conagra Advisory Regarding Pot Pies Linked to Salmonella Outbreak
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)...  Research and Markets ( http://www.researchandmarkets.com/research/6k27gw/dental ) has announced the ... Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 ... (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ) ... in order to treat dental impairments, for tooth restoration ...
(Date:1/15/2014)... IRVING, Texas , Jan. 15, 2014  Novation, the ... company, awarded several new IT value-added reseller (VAR) national ... with IT goods and services at lower costs. These ... value-added services such as initiative assistance and ongoing IT ...
(Date:1/15/2014)... 2014 Shire plc (LSE: SHP, NASDAQ: ... Trading (OFT) approval condition to the announced tender offer for all ... As a result of the waiver, the transaction is no ... tender offer on January 24, 2014 following the currently scheduled expiration ...
Breaking Medicine Technology:Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3
... Pharmaceuticals, Inc. (Nasdaq: CADX ) today announced that ... of its common stock at a price to the public ... of the shares, after deducting the underwriting discounts and commissions ... million.  Cadence has granted the underwriters for the offering a ...
... NEW YORK, Nov. 15, 2011 Reportlinker.com ... is available in its catalogue: ... East Asia ... analysis of four pharmaceutical markets that present ...
Cached Medicine Technology:Cadence Pharmaceuticals Announces Pricing of Public Offering of Common Stock 2Cadence Pharmaceuticals Announces Pricing of Public Offering of Common Stock 3The Outlook for Pharmaceuticals in North East Asia 2The Outlook for Pharmaceuticals in North East Asia 3The Outlook for Pharmaceuticals in North East Asia 4
(Date:4/18/2014)... one of your worst memories? How did it make ... during a negative personal experience, such as how sad ... to emotional distress, especially when you can,t stop thinking ... up, thinking about the context of the memories, rather ... effective way to alleviate the negative effects of these ...
(Date:4/18/2014)... Fraser University psychologists have made a brain-related discovery ... attention-deficit disorders. , This discovery opens up the ... or suppress a specific brain activity that the ... , The Journal of Neuroscience has ... John McDonald, an associate professor of psychology and ...
(Date:4/18/2014)... . A ... A team led by Ludwik Leibler from the Laboratoire ... Letourneur from the Laboratoire Recherche Vasculaire Translationnelle (INSERM/Universits Paris ... principle of adhesion by aqueous solutions of nanoparticles can ... tissues. This easy-to-use gluing method has been tested on ...
(Date:4/17/2014)... in benign prostate tissue was associated with high-grade, ... found even in those with low prostate-specific antigen ... Cancer Epidemiology, Biomarkers & Prevention , a ... , An analysis of prostate tissue biopsies collected ... the Prostate Cancer Prevention Trial (PCPT) found that ...
(Date:4/17/2014)... first genetic variant specifically associated with the risk ... 10-15 per cent of all breast cancer cases. ... cancer sub-type, called invasive lobular carcinoma, gives researchers ... particular kind of breast cancer, which can be ... (Thursday) in the journal PloS Genetics , ...
Breaking Medicine News(10 mins):Health News:New study suggests a better way to deal with bad memories 2Health News:New study suggests a better way to deal with bad memories 3Health News:Scientists discover brain's anti-distraction system 2Health News:Innovative strategy to facilitate organ repair 2Health News:Innovative strategy to facilitate organ repair 3Health News:Chronic inflammation may be linked to aggressive prostate cancer 2Health News:Chronic inflammation may be linked to aggressive prostate cancer 3Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 3
... Nov. 26 David B. Snow,chairman & chief executive ... to address the Merrill Lynch & Co., Inc. 2007 ... presentation at Merrill Lynch headquarters, New York, will begin ... and Richard J.,Rubino, CPA, Medco,s controller and chief accounting ...
... CHICAGO, Nov. 26 All-terrain vehicles (ATVs) pose a,serious ... largest study ever,conducted of ATV injuries in children. The ... Radiological Society of North America (RSNA)., "Our experience ... be restricted," said Chetan C. Shah, M.D., radiology fellow ...
... women have a different understanding of screening mammography ... the findings of a Boston University Medical Center ... the Radiological Society of North America (RSNA). , ... ethnic and socioeconomic groups, said Nazia F. Jafri, ...
... PHILADELPHIA Researchers at the University of Pennsylvania School ... transcranial magnetic stimulation (TMS) a non-invasive technique that ... through the scalp is a safe and effective, ... major depression who have tried other treatment options without ...
... and its there in bright medical images: evidence of ... secondhand cigarette smoke. For the first time, researchers have ... but not previously detectable with medical imaging tools. ... public health efforts to restrict secondhand smoke. , ...
... FAAN, FAHA, a clinical professor of neurology at Boston ... the Framingham Heart Study, was recently awarded the Stroke ... award was presented at the AHAs recent Scientific Sessions ... Award recognizes and encourages those who actively work to ...
Cached Medicine News:Health News:Medco CEO to Present at the Merrill Lynch & Co., Inc. 2007 Health Services Investor Conference 2Health News:Injury Report Shows All-Terrain Vehicles Not Child's Play 2Health News:Injury Report Shows All-Terrain Vehicles Not Child's Play 3Health News:Attitudes toward mammography differ across ethnicities, cultures, backgrounds 2Health News:Penn research shows transcranial magnetic stimulation effective in treating major depression 2Health News:Secondhand smoke damages lungs, MRIs show 2
... and removal in the urinary tract. The nitinol ... shape following extreme torsion. The unique tipless design ... basket to open at the base of the ... reduces the likelihood of mucosal damage and perforation. ...
... Filiform Spiral Tip 12 Inch , 20 ... female thread. Available in 3,4,5 6Fr. These ... strong but flexible polymer material and have ... other brands. They are manufactured to the ...
... for stone manipulation and removal in the urinary ... Delta Wire. The revolutionary triangular shape of Delta ... largest possible wire mass. The superior mass of ... qualities of nitinol alloy, creates a basket with ...
... SILASTIC Brand Latex Foley Catheter, Smooth, ... build-up, Firm, but flexible, latex-based construction ... length - round tip with two ... (336xx) or two staggered eyes and ...
Medicine Products: