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Top Ranked Equity Analyst Joins Vital Therapies, Inc.
Date:3/19/2012

tion the company to the public markets and in implementing our upcoming pivotal studies for marketing approval. His intimate knowledge of both clinical practice for liver disease and the breadth of new technologies under development is a compliment to the potential of ELAD in liver therapy."

About Vital Therapies, Inc.

Vital Therapies, Inc. is a private development-stage biotechnology company based in San Diego, California.  The company is developing ELAD®, an extracorporeal liver support system which functions by processing toxins and synthesizing proteins and metabolites that are the key processes of normal human liver function, and represents the first human allogeneic cellular therapy for acute liver failure.  Vital Therapies has completed seven clinical trials including a pivotal trial in China, which was used to file for marketing approval in China and which remains pending.  A US/EU pivotal trial plan to secure BLA and MAA approval has received written guidance from FDA and EMA. The first protocol under this plan, for a survival trial in acute alcoholic hepatitis, has been allowed by FDA. The trial should start soon.

About ELAD

ELAD is a bedside system whose central component is four cartridges containing 440 grams of immortalized human liver cells and 32,000 hollow fibers.  The patient's plasma flows inside of the hollow fibers to allow two-way transfer of metabolites.  During ELAD therapy the cells metabolize toxins and synthesize proteins and other liver specific products essential for life. The ELAD cell cartridges are produced at VTI's GMP-compliant facility in San Diego, California.

ELAD is a trademark of Vital Therapies, Inc.

STARMINE is a trademark of Thomson Reuters


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