Navigation Links
Tolerx Presents Baseline Data from DEFEND-1 Study Validating C-Peptide as Critical Clinical Measure for New-Onset Type 1 Diabetes
Date:6/28/2010

body may work in patients with type 1 diabetes who have residual beta cells by blocking the function of effector T cells that mistakenly attack and destroy insulin-producing beta cells, while stimulating regulatory T cells that are understood to protect against effector T cell damage, thus preserving the beta cells' ability to make insulin. 

About Tolerx

Tolerx, Inc., a world leader in the understanding of T cell function, is developing novel therapies intended to treat autoimmune diseases, diabetes, and cancer by specifically modulating T cell activity.  The company's pipeline includes its lead candidate, otelixizumab, a targeted T cell immunomodulator in Phase 3 development for the treatment of type 1 diabetes that is partnered with GlaxoSmithKline.  TRX1, a Phase 1 candidate, is a nonlytic anti-CD4 antibody that is being developed for the treatment of aberrant or untoward immune responses.  The company also has three pre-clinical candidates, TRX518, TRX585 and TRX385, that enhance immune responses and as such are being evaluated for potential benefit in the treatment of cancer and chronic infections. Tolerx is a privately held company headquartered in Cambridge, MA USA.  For more information, please visit www.tolerx.com.


'/>"/>
SOURCE Tolerx, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Tolerx Presents Preclinical Data on Novel T-cell Modulator, TRX518, for Antitumor Immune Response at Federation of Clinical Immunology Societies Scientific Meeting
2. Tolerx Presents Data at 69th Scientific Sessions of the American Diabetes Association
3. Tolerx Initiates Dosing of Otelixizumab, a Novel Type 1 Diabetes Agent, in DEFEND, a Phase 3 Clinical Trial
4. Tolerx Announces Achievement of Milestones upon anti-CD4 Antibody Program Advancement and Initiation of Phase 1 Clinical Trial
5. Tolerx Advancing Novel Type 1 Diabetes Agent into Phase III Clinical Trial Program Following End of Phase II FDA Meeting
6. Tolerx Achieves Milestone with Completion of Phase Ib Clinical Study of TRX1 in Cutaneous Lupus Erythematosus
7. Lexicon Presents Data Describing LX4211 Positive Phase 2 Clinical Results and Novel Mechanism of Action for Type 2 Diabetes
8. Onyx Pharmaceuticals Presents Interim Results of Phase 1b Carfilzomib Combination Trial
9. Lilly Presents New Data in Advanced Melanoma - A Difficult-To-Treat Cancer That Causes Majority of Skin Cancer Deaths
10. Mpex Pharmaceuticals Presents Positive Phase 2 Clinical Trial Results of Aeroquin(TM) (MP-376) Treatment in Cystic Fibrosis Patients
11. Spectros Presents at the Pediatric Academic Societies (PAS) National Conference 2010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... , Sept. 15, 2014  Patients in today,s ... care more frequently in an outpatient setting versus a ... curve and to ensure that patients continue to receive ... the launch of its new internal medicine residency program. ... more often in office, clinic and even virtual settings. ...
(Date:9/15/2014)... /PRNewswire-iReach/ -- On September 8, 2014, Dr. ... a Citizen Petition to Dr. Margaret Hamburg ... another Black Box Warning to Levaquin, Cipro, and ... a Black Box Warning for the following psychiatric ... or acts, loss of consciousness, delirium, depressed level ...
(Date:9/15/2014)... , Sept. 15, 2014  Decision ... MedTech Physician™ 2014, finds that online information ... for brands to differentiate their offering and ... medical device purchasing decisions rely on websites, ... learning about devices—and these physicians are looking ...
Breaking Medicine Technology:Kaiser Permanente Hawaii Launches New Internal Medicine Residency Program 2Kaiser Permanente Hawaii Launches New Internal Medicine Residency Program 3Quinolone Vigilance Foundation Supports Citizen Petition Requesting Another Black Box Warning for Levaquin, Cipro, Avelox 2Quinolone Vigilance Foundation Supports Citizen Petition Requesting Another Black Box Warning for Levaquin, Cipro, Avelox 3Physician device decision-makers show strong demand for device manufacturer digital content and support 2Physician device decision-makers show strong demand for device manufacturer digital content and support 3
(Date:9/16/2014)... September 16, 2014 Antioch University has ... Arts in Clinical Mental Health Counseling from Antioch ... list of programs offered through Antioch’s online campus. The ... January 2015. , "Antioch University New England’s MA in ... the field and a track record of preparing graduates ...
(Date:9/16/2014)... The rapidly increasing cost of compounded medications has ... PBMs as spending on these specialized drugs has catapulted ... concentrated, patient-specific practice, compounding has become commonplace in the ... Inc. (AIS), “Controlling the Cost of Compounded Medications: ... one leading health insurer and its internal PBM are ...
(Date:9/16/2014)... Madisonville, Louisiana (PRWEB) September 16, 2014 ... packaging for one of its most popular products - ... been designed to educate the general public about the ... weight management and building lean muscle mass. As well ... now detail product benefits, supplement facts, and nutritional information ...
(Date:9/16/2014)... 16, 2014 The Living Ethics lecture ... fall. Reflecting on what it means to live in ... investigates unique and thought-provoking topics. , “The Museum’s job ... to look at their world differently. The Living ... stage for truly enlightening dialogue,” says Richard Conti, Chief ...
(Date:9/16/2014)... September 16, 2014 DiaperBuys, a national ... ‘Healthy Aging’ Month this September. Healthy Aging Month was ... across the nation on the positive aspects of growing ... with conditions or side effects from medications that cause ... Outreach Manager for DiaperBuys.com. “This can seem daunting to ...
Breaking Medicine News(10 mins):Health News:Antioch University Launches Online Master’s Degree Program in Clinical Mental Health Counseling 2Health News:Sept. 25 Webinar to Offer Health Plan, Employer Strategies to Control Compounded Medication Costs 2Health News:BQuick Nutrition Announces Newly Branded BURN Clarinol CLA Powder 2Health News:BQuick Nutrition Announces Newly Branded BURN Clarinol CLA Powder 3Health News:Expanding Community Vision at the Science Museum of Virginia 2Health News:DiaperBuys Honors ‘Healthy Aging’ Month throughout September 2Health News:DiaperBuys Honors ‘Healthy Aging’ Month throughout September 3
... Md., Dec. 4 Nabi,Biopharmaceuticals (Nasdaq: ... completed the,sale of assets constituting its Biologics ... a wholly-owned subsidiary of Biotest,AG, for $185 ... arrangements described,below, Biotest has acquired or will ...
... 4 ConsumerLab.com, LLC claims to,be a leading provider ... and healthcare professionals evaluate health, wellness, and,nutrition products. ... of,Revatrol, a red-wine 100MG resveratrol supplement -- is ... by ConsumerLab.com on red wine,supplements analyzed a formulation ...
... more than one in ten infants in the U.S. is ... problems associated with premature births is brittle bones, or osteopenia ... in the infant, and osteoporosis later in life. , ... that aims to make preemies bones stronger. Dr. Dan Nemet ...
... Florida State University professor will share a $3.3 million ... Vermont to develop an innovative method that will help ... psychology Professor Brad Schmidt and UVM psychology Professor Michael ... each campus -- to participate in the study over ...
... In response to the growing body of research ... for Cancer Research (AACR) announces the launch of a ... submissions of papers. This important new journal is the ... from preclinical research to clinical trials. , In the ...
... that only vertebrates have sophisticated adaptive immune systems that ... being infected by them just once has been revised ... also have a form of immune memory that protects ... encountered. This was just one of the striking discoveries ...
Cached Medicine News:Health News:Nabi Biopharmaceuticals Completes Sale of Nabi Biologics to Biotest AG 2Health News:Nabi Biopharmaceuticals Completes Sale of Nabi Biologics to Biotest AG 3Health News:Renaissance Health Publishing, LLC Asks Key Credibility Questions of ConsumerLab.com 2Health News:Tel Aviv University gives preemies a fighting chance 2Health News:FSU researcher lands $3.3 million grant to help smokers kick habit 2Health News:AACR introduces Cancer Prevention Research 2Health News:AACR introduces Cancer Prevention Research 3Health News:Violent sex acts boost insect's immunity system 2Health News:Violent sex acts boost insect's immunity system 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: