Navigation Links
Tolero Pharmaceuticals announces Worldwide Agreement with Sanofi for the In-license of Alvocidib (Flavopiridol)
Date:5/1/2013

SALT LAKE CITY, May 1, 2013 /PRNewswire-iReach/ -- Tolero Pharmaceuticals, Inc., a biopharmaceutical company focused on the discovery and development of novel therapeutics to treat cancer and other serious human diseases, today announced that it has entered into a license agreement with Sanofi in which it received exclusive worldwide rights to develop and commercialize alvocidib (flavopiridol). Alvocidib is a small molecule inhibitor of the cyclin-dependent kinases that has demonstrated activity in clinical trials in several malignancies, including chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML).

Under the terms of the agreement, Tolero Pharmaceuticals will pay Sanofi an undisclosed upfront payment, and future payments on the successful achievement of milestones related to the commercialization of alvocidib. Sanofi will also receive tiered royalties on sales of alvocidib and maintains certain negotiation rights with respect to manufacturing the pharmaceutical product for Tolero and becoming a commercialization partner.

"We are tremendously excited about this new opportunity and feel fortunate to partner with Sanofi on this highly promising asset with near-term commercialization potential," said Dallin Anderson , Chairman and President of Tolero.

Dr. David Bearss , Tolero's Chief Executive Officer, added, "Alvocidib has been evaluated in more than forty Phase I and Phase II clinical trials and has demonstrated remarkable activity in multiple studies of acute and chronic leukemia as both a single agent and in combination with chemotherapy." Tolero continues to advance various preclinical assets targeting areas of unmet need and strong commercial opportunity in the treatment of various cancers.

About Tolero Pharmaceuticals

Tolero is a biopharmaceutical company dedicated to the discovery and development of novel therapeutic
'/>"/>

SOURCE Tolero Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Savient Pharmaceuticals to Hold First Quarter 2012 Financial Results Conference Call on Wednesday, May 9, 2012
2. Auxilium Pharmaceuticals to Present at the Deutsche Bank 37th Annual Healthcare Conference
3. Nouveau Life Pharmaceuticals (HRID) Contracts with U.S. Manufacturer to Produce New Female Supplement
4. BioElectronics Survey Indicates a Five-Fold Superior Pain Relief Compared to OTC Pharmaceuticals
5. Icahn Issues Statement Regarding Amylin Pharmaceuticals
6. Almost 50 Percent of the Glaucoma Patient Population Remains Untreated, Signifying a Vast Market for Glaucoma Pharmaceuticals, Finds Frost & Sullivan
7. Omthera Pharmaceuticals Announces Positive Top-Line Results from Phase 3 EVOLVE Study
8. Onyx Pharmaceuticals Announces FDA Advisory Committee to Review Carfilzomib for the Treatment of Patients with Relapsed and Refractory Multiple Myeloma
9. Jazz Pharmaceuticals Announces First Quarter 2012 Financial Results Conference Call On May 8, 2012
10. Inovio Pharmaceuticals Granted U.S. Patent Protection for Synthetic Vaccine for Cervical Dysplasia and Cancer
11. Avanir Pharmaceuticals To Present at Three Conferences In May
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/29/2014)... SAN DIEGO , 29 septembre ... désignée Daiichi Sankyo) (TSE : 4568) et Ambit Biosciences ... d,un accord de fusion définitif en vertu duquel ... actions ordinaires en circulation d,Ambit Biosciences à 15 ... d,une offre publique d,achat qui sera suivie d,une ...
(Date:9/29/2014)...  Bob Pack, who lost his two young children ... Medical Association to immediately cease airing a television ad ... Mercury News called "shamelessly deceptive" and of which the ... believe about the measure is wrong." ... that doctors check California,s existing ...
(Date:9/29/2014)... Sept. 29, 2014  Volcano Corporation (Nasdaq: ... improving patient and economic outcomes on a global ... coronary and peripheral visualization, physiology diagnostics and therapies, ... Board of Directors from Engaged Capital, LLC.  The ... Volcano welcomes the perspectives of its ...
Breaking Medicine Technology:Daiichi Sankyo va acquérir Ambit Biosciences 2Daiichi Sankyo va acquérir Ambit Biosciences 3Daiichi Sankyo va acquérir Ambit Biosciences 4Daiichi Sankyo va acquérir Ambit Biosciences 5Daiichi Sankyo va acquérir Ambit Biosciences 6Daiichi Sankyo va acquérir Ambit Biosciences 7Daiichi Sankyo va acquérir Ambit Biosciences 8Daiichi Sankyo va acquérir Ambit Biosciences 9Father Calls On CA Medical Assn To Pull TV Ad Called "Jaw-Droppingly Deceptive" and "Baloney" By LA Times & "Shamelessly Deceptive" By San Jose Mercury News, Says Consumer Watchdog Campaign 2Father Calls On CA Medical Assn To Pull TV Ad Called "Jaw-Droppingly Deceptive" and "Baloney" By LA Times & "Shamelessly Deceptive" By San Jose Mercury News, Says Consumer Watchdog Campaign 3Father Calls On CA Medical Assn To Pull TV Ad Called "Jaw-Droppingly Deceptive" and "Baloney" By LA Times & "Shamelessly Deceptive" By San Jose Mercury News, Says Consumer Watchdog Campaign 4Father Calls On CA Medical Assn To Pull TV Ad Called "Jaw-Droppingly Deceptive" and "Baloney" By LA Times & "Shamelessly Deceptive" By San Jose Mercury News, Says Consumer Watchdog Campaign 5Volcano Issues Statement Regarding Letter From Engaged Capital 2Volcano Issues Statement Regarding Letter From Engaged Capital 3
... ... if (typeof(lpUnit)==,undefined,) var ... var shortURL = ""; BitlyCB.alertResponse = function(data) ... grab the first one. for (var r in data.results) { first_result = data.results[r]; break; } for (var ...
... (Nasdaq: KOOLD ), a leading supplier of innovative ... said today that revenues for the fourth quarter of fiscal ... the same quarter a year ago. Revenues in the third ... Company recorded disposable revenues of $4.8 million in the fourth ...
Cached Medicine Technology:Creabilis Appoints George F. Horner III as its Chairman 2Creabilis Appoints George F. Horner III as its Chairman 3Creabilis Appoints George F. Horner III as its Chairman 4Creabilis Appoints George F. Horner III as its Chairman 5Creabilis Appoints George F. Horner III as its Chairman 6Creabilis Appoints George F. Horner III as its Chairman 7ThermoGenesis Announces Fourth Quarter Revenues of $7.2 Million; Reduces Net Loss to $171,000 2ThermoGenesis Announces Fourth Quarter Revenues of $7.2 Million; Reduces Net Loss to $171,000 3ThermoGenesis Announces Fourth Quarter Revenues of $7.2 Million; Reduces Net Loss to $171,000 4ThermoGenesis Announces Fourth Quarter Revenues of $7.2 Million; Reduces Net Loss to $171,000 5ThermoGenesis Announces Fourth Quarter Revenues of $7.2 Million; Reduces Net Loss to $171,000 6ThermoGenesis Announces Fourth Quarter Revenues of $7.2 Million; Reduces Net Loss to $171,000 7
(Date:9/30/2014)... (PRWEB) September 30, 2014 A trailblazer at ... and seeks out upcoming medical breakthroughs in spine repairs. ... has seen in his patients in which he has implanted ... and its components are state-of-the art and mimic normal human ... Mobi-C has also been proven to be an exceptional replacement ...
(Date:9/30/2014)... Influenza is a significant clinical and ... the efficacy of therapy, minimize overuse of antibiotics, conserve ... healthcare settings. Diagnostic tests available today vary widely in ... your laboratory makes in selecting the correct test, along ... key to effective use of influenza diagnostics. , ...
(Date:9/30/2014)... North Carolina (PRWEB) September 30, 2014 ... 200, a 203 mile relay race beginning in Raleigh, ... and awareness for Alzheimer’s support and care. , Associate ... Seniors Guide – the comprehensive senior resource for the ... 13 years. , Seniors Guide will be helping their ...
(Date:9/30/2014)... Dogs are social animals, and love to go everywhere with ... travelling from place to place. Many dog owners choose to ... this is not only unsafe for the dog, but unsafe ... shares with readers why keeping a dog restrained in a ... ways a dog can become injured by riding freely in ...
(Date:9/30/2014)... 30, 2014 Doctors often order breast ultrasounds ... results. Most breast ultrasounds are done at a specialized ... Imaging in Miami . The Center for Diagnostic Imaging ... to MRI. Most patients find ultrasounds to be more ... do not have to remain perfectly still. , ...
Breaking Medicine News(10 mins):Health News:Alere Webinar Spotlights Optimal Flu Diagnostics to Keep Your Lab Ahead of the Curve 2Health News:Alere Webinar Spotlights Optimal Flu Diagnostics to Keep Your Lab Ahead of the Curve 3Health News:Seniors Guide To Run in 203 Mile Alzheimer’s Awareness Relay in Raleigh, North Carolina 2Health News:Seniors Guide To Run in 203 Mile Alzheimer’s Awareness Relay in Raleigh, North Carolina 3Health News:Royal Flush Havanese Offers Tops On the Importance of Restraining Dogs In Cars 2Health News:Royal Flush Havanese Offers Tops On the Importance of Restraining Dogs In Cars 3Health News:Breast Ultrasounds Are a Comfortable and Convenient Option for Patients and Referring Doctors 2
... Nov. 19 2009 has been a monumental year ... "moneyvation," from QUITPLAN Services, QuitCash Challenge, helped the 31-year-old ... win The Challenge. Nearly 2,000 Minnesotans, including Doug, attempted ... to win the $5,000 grand prize. , On Thursday, ...
... , Official Statement by Teamsters General President Jim ... President Jim Hoffa issued the following statement today about the ... higher-cost health plans that will mean a huge middle-class tax ... that would impose an excise tax on insurers for higher-cost ...
... , FAIRFIELD, N.J., Nov. 19 Monogram Energy, Inc. ... completed the acquisition of Triad Therapeutics, Inc. ("Triad"), which ... the terms of the Stock Purchase and Recapitalization Agreement, ... of Triad in exchange for approximately 95% ownership to ...
... who directs the University of Southern California Center ... effort to evaluate robots as exercise coaches for adults ... elderly. The effort, entitled "Robot Motivator: Towards Adaptive ... influence of virtual social characters on people,s motivation to ...
... , New Video Educates Kids on How to Prevent ... learn the five things that they can do to prevent the ... a new music video released today by the Department of Health. ... the simple ways to prevent H1N1 flu in a manner that ...
... WASHINGTON, Nov. 19 Now that a bill has been ... of the Democratic Caucus to vote to allow debate to ... promise of quality, affordable health care for all. , "Majority ... forward," said USAction Program Director Alan Charney. "Now it,s time ...
Cached Medicine News:Health News:First-Time Father-to-Be Quits Smoking, Wins $5,000 in The QuitCash Challenge(TM) 2Health News:First-Time Father-to-Be Quits Smoking, Wins $5,000 in The QuitCash Challenge(TM) 3Health News:Monogram Energy, Inc. Acquires Triad Therapeutics, Inc. 2Health News:Pennsylvania Department of Health Releases H1N1 Flu Prevention Music Video 2Health News:60 Votes: Democratic Caucus Must Move Forward With Promise of Quality, Affordable Health Care for All With a Public Insurance Option 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: