Navigation Links
Tolero Pharmaceuticals announces Worldwide Agreement with Sanofi for the In-license of Alvocidib (Flavopiridol)
Date:5/1/2013

SALT LAKE CITY, May 1, 2013 /PRNewswire-iReach/ -- Tolero Pharmaceuticals, Inc., a biopharmaceutical company focused on the discovery and development of novel therapeutics to treat cancer and other serious human diseases, today announced that it has entered into a license agreement with Sanofi in which it received exclusive worldwide rights to develop and commercialize alvocidib (flavopiridol). Alvocidib is a small molecule inhibitor of the cyclin-dependent kinases that has demonstrated activity in clinical trials in several malignancies, including chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML).

Under the terms of the agreement, Tolero Pharmaceuticals will pay Sanofi an undisclosed upfront payment, and future payments on the successful achievement of milestones related to the commercialization of alvocidib. Sanofi will also receive tiered royalties on sales of alvocidib and maintains certain negotiation rights with respect to manufacturing the pharmaceutical product for Tolero and becoming a commercialization partner.

"We are tremendously excited about this new opportunity and feel fortunate to partner with Sanofi on this highly promising asset with near-term commercialization potential," said Dallin Anderson , Chairman and President of Tolero.

Dr. David Bearss , Tolero's Chief Executive Officer, added, "Alvocidib has been evaluated in more than forty Phase I and Phase II clinical trials and has demonstrated remarkable activity in multiple studies of acute and chronic leukemia as both a single agent and in combination with chemotherapy." Tolero continues to advance various preclinical assets targeting areas of unmet need and strong commercial opportunity in the treatment of various cancers.

About Tolero Pharmaceuticals

Tolero is a biopharmaceutical company dedicated to the discovery and development of novel therapeutic
'/>"/>

SOURCE Tolero Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Savient Pharmaceuticals to Hold First Quarter 2012 Financial Results Conference Call on Wednesday, May 9, 2012
2. Auxilium Pharmaceuticals to Present at the Deutsche Bank 37th Annual Healthcare Conference
3. Nouveau Life Pharmaceuticals (HRID) Contracts with U.S. Manufacturer to Produce New Female Supplement
4. BioElectronics Survey Indicates a Five-Fold Superior Pain Relief Compared to OTC Pharmaceuticals
5. Icahn Issues Statement Regarding Amylin Pharmaceuticals
6. Almost 50 Percent of the Glaucoma Patient Population Remains Untreated, Signifying a Vast Market for Glaucoma Pharmaceuticals, Finds Frost & Sullivan
7. Omthera Pharmaceuticals Announces Positive Top-Line Results from Phase 3 EVOLVE Study
8. Onyx Pharmaceuticals Announces FDA Advisory Committee to Review Carfilzomib for the Treatment of Patients with Relapsed and Refractory Multiple Myeloma
9. Jazz Pharmaceuticals Announces First Quarter 2012 Financial Results Conference Call On May 8, 2012
10. Inovio Pharmaceuticals Granted U.S. Patent Protection for Synthetic Vaccine for Cervical Dysplasia and Cancer
11. Avanir Pharmaceuticals To Present at Three Conferences In May
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... Jan. 15, 2014  Manufacturers, suppliers and distributors of ... to protect their most important business assets, intellectual ... ) Because of the highly-competitive nature ... one of the most litigious industry sectors of ...
(Date:1/15/2014)... Medical is very pleased to announce the appointment of Mr. ... Officer.  Mark was promoted from his current role of Chief ... facilities in Massachusetts , Mississippi ... in 2012 with 20+ years of broad-based operations, sales, engineering ...
(Date:1/15/2014)... , Jan. 15, 2014  Echo Therapeutics, Inc. (Nasdaq: ... its Symphony® CGM System as a non-invasive, wireless continuous ... Doman , Executive Chairman and Interim CEO of Echo ... Tenth Annual Equity Conference. Mr. Doman ...
Breaking Medicine Technology:Intellectual Property Insurance for Medical-related Products and Services 2Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 2Echo Therapeutics to Present at the Noble Financial Capital Markets' Tenth Annual Equity Conference 3
(Date:4/18/2014)... device is being prepped to enter the battle ... of certain diseases in remote areas, thanks in ... investigations aboard the International Space Station on the ... concept of capillary flow to diagnose infectious diseases ... Ph.D., a researcher at Northwestern University in Evanston, ...
(Date:4/18/2014)... Hopkins University School of Medicine researchers have been awarded ... diabetes, Novo Nordisk announced this month. Of the 110 ... Obesity Biologics Science Forum Program, only four projects were ... researchers. They are Jonathan Powell, M.D., Ph.D.; G. William ... Jonathan Powell, a professor of oncology, will use his ...
(Date:4/18/2014)... a brain-related discovery that could revolutionize doctors, perception ... opens up the possibility that environmental and/or genetic ... activity that the researchers have identified as helping ... Neuroscience has just published a paper about ... of psychology and his doctoral student John Gaspar, ...
(Date:4/18/2014)... to potential new treatments for breaking the cycle of ... or scarring, is a hallmark of the disease, and ... to serious organ damage and, in some cases, death. ... findings made by Swati Bhattacharyya, PhD, research assistant professor ... protein plays in promoting fibrosis. , "Our results ...
(Date:4/17/2014)... first genetic variant specifically associated with the risk ... 10-15 per cent of all breast cancer cases. ... cancer sub-type, called invasive lobular carcinoma, gives researchers ... particular kind of breast cancer, which can be ... (Thursday) in the journal PloS Genetics , ...
Breaking Medicine News(10 mins):Health News:Space-tested fluid flow concept advances infectious disease diagnoses 2Health News:Space-tested fluid flow concept advances infectious disease diagnoses 3Health News:Scientists discover brain's anti-distraction system 2Health News:New clues on tissue scarring in scleroderma 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 3
... long-term contract to provide medical billing services for the Seton Family ... delivering quality service and affordable medical billing solutions are cited in ... , ... Austin, Texas (PRWEB) May 10, 2009 -- ...
... Integrated Solution for Mail Server Data Protection and Quick Recovery ... ... CA and Melville, NY (PRWEB) May 11, 2009 -- MessageSolution, ... solutions for electronic discovery, litigation support, compliance and storage management, ...
... wipes are alcohol based. Over-use of hand sanitizers cause more health ... open a direct pathway to the human bloodstream. Q-Based Healthcare ... ... Erath, Louisiana (PRWEB) May 11, 2009 -- A Louisiana company, ...
... Released During National Women,s Health Week Points to Importance ... released today on gender-based differences in mental health shows ... suffer from major depression. The report addresses many ... trauma and violence can have on long term mental ...
... 11 , - New Hayfever Relief ... Available on the Internet , - With ... 200 years ago, however, it,s believed that,it now affects as many ... do suffer,with hayfever, it,s either complete misery with symptoms such as ...
... areas are more likely to develop late-stage cancer than those ... conclusion of a new study published in the June 15, ... the American Cancer Society. The study,s results indicate a need ... Diagnosing cancer at an early stage can improve outcomes. ...
Cached Medicine News:Health News:AMPM to Provide Medical Billing Services for Seton Community Health Centers in Austin 2Health News:MessageSolution and FalconStor Deliver Turnkey Solution for Enterprise Archiving, DR, and High-Availability 2Health News:MessageSolution and FalconStor Deliver Turnkey Solution for Enterprise Archiving, DR, and High-Availability 3Health News:MessageSolution and FalconStor Deliver Turnkey Solution for Enterprise Archiving, DR, and High-Availability 4Health News:MessageSolution and FalconStor Deliver Turnkey Solution for Enterprise Archiving, DR, and High-Availability 5Health News:Q-Based Healthcare Warns: Hand Sanitizers Increase Risk of Swine Flu Exposure 2Health News:Q-Based Healthcare Warns: Hand Sanitizers Increase Risk of Swine Flu Exposure 3Health News:Women at Greater Risk for Depression and Anxiety 2Health News:Women at Greater Risk for Depression and Anxiety 3Health News:'Qu-Chi' Acupressure Band Gives Hayfever Misery the Elbow 2Health News:'Qu-Chi' Acupressure Band Gives Hayfever Misery the Elbow 3Health News:City-dwellers have higher risk of late-stage cancer than rural residents 2
Eliminate preanalytical errors with automated QC module....
Non-invasive and continuous tcpCO2 and tcpO2 patient monitoring....
... Submit your analyzer data via the ... a worldwide peer group. , ... you to perform statistical analysis of ... often as you like. Peer-group data ...
Automated QC module...
Medicine Products: