Navigation Links
ThromboGenics and BioInvent to Receive EUR10 Million Milestone as Partner Roche Begins New Clinical Study with TB-403
Date:5/17/2010

LEUVEN, Belgium and LUND, Sweden, May 17, 2010 /PRNewswire-FirstCall/ --

- Trial to Study Patients with Colorectal and Ovarian Cancer

ThromboGenics NV (Euronext Brussels: THR) and BioInvent International AB (OMXS: BINV) announce today that their partner Roche (SIX: RO, ROG; OTCQX: RHHBY) will begin an imaging study with the novel anti-cancer antibody TB-403 (RG7334) in patients with metastatic, treatment-refractory, colorectal and ovarian cancers. ThromboGenics and co-development partner BioInvent will receive a milestone payment of EUR10 million from Roche under the terms of the strategic alliance agreement signed in June 2008. ThromboGenics, which discovered TB-403, receives 60% and BioInvent 40% of all revenue from the alliance with Roche for this anti-cancer antibody.

This trial is a multi-centre, open-label (monotherapy), dose-finding study with intravenous TB-403. The primary objective of the study will be to establish the TB-403 concentration-pharmacodynamic (PD) effect relationship using DCE-MRI (dynamic contrast-enhanced magnetic resonance imaging) and to identify the minimally PD effective dose. The trial will recruit up to 50 patients across three European sites.

With the start of this study, Roche will assume responsibility for all future development of TB-403, continuing the work started by ThromboGenics and BioInvent. A Joint Steering Committee made up of representatives from Roche, ThromboGenics and BioInvent will continue to oversee research and development activities. In addition, Roche will continue to provide funding to ThromboGenics and BioInvent for re
'/>"/>

SOURCE ThromboGenics NV
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. ThromboGenics Completes Patient Enrolment in the Phase IIb Trial of Microplasmin in Vitrectomy (MIVI III)
2. ThromboGenics Announces Promising Results of MITI IV Phase II Trial in the Treatment of Acute Stroke with Microplasmin
3. ThromboGenics Begins Phase III Program With Microplasmin for the Non-surgical Treatment of Back of the Eye Disease
4. ThromboGenics and BioInvent Receive Technology Transfer Success Fee From Roche for the Novel Anti-Cancer Antibody, TB-403 (Anti-PIGF)
5. ThromboGenics Completes Patient Enrolment for Phase II Trial of Microplasmin for the Treatment of Diabetic Macular Edema (MIVI II DME)
6. ThromboGenics Microplasmin Phase III Program Progressing According to Schedule
7. ThromboGenics and BioInvent Start Recruitment of Second 100 Patient Cohort in Phase II DVT Prophylaxis Study With TB-402
8. ThromboGenics Completes Patient Enrolment in US Phase III Trial of Microplasmin for the Non-Surgical Treatment of Eye Disease
9. ThromboGenics and BioInvent Complete Patient Recruitment of Phase II DVT Prophylaxis Study With Anti-Factor VIII (TB-402)
10. ThromboGenics Completes Patient Enrolment of Second Phase III Trial of Microplasmin for the Non-Surgical Treatment of Eye Disease
11. ThromboGenics Announces Start of Phase II Trial of Microplasmin for the Treatment of Age-Related Macular Degeneration (AMD)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)...   AcelRx Pharmaceuticals, Inc.  (Nasdaq: ACRX ... and commercialization of innovative therapies for the treatment of ... for Zalviso remains July 27, 2014.  The ... the Food and Drug Administration (FDA) had approved Zalviso.  ... notification to the company from the FDA regarding the ...
(Date:7/24/2014)... PLAINFIELD, N.J. , July 24, 2014  PTC ... that the Company will host a webcast conference call ... provide an update on the company,s business and outlook ... before the opening of the market. ... (domestic) or (973) 935-8152 (international) five minutes prior to ...
(Date:7/24/2014)... , Deutschland, und MARSEILLE ... -- , Weltweite ... ermöglicht QIAGEN die Entwicklung von Tests ... für Blutkrebs  Neuer Test weist ... mit Knochenmarkserkrankungen (myelodysplastischen Syndromen) einen günstigen Krankheitsverlauf ...
Breaking Medicine Technology:AcelRx Pharmaceuticals Confirms July 27, 2014 PDUFA Date for Zalviso 2QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 2QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 3QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 4QIAGEN erweitert Pipeline für die personalisierte Medizin um vielversprechende genomische Biomarker zur Prognosebestimmung bei Blutkrebsbehandlungen 5
(Date:7/25/2014)... A new study conducted by the Hospital for Sick ... all children in the survey under the age of four had ... children during the years of 2011 and 2013. The children in ... final result was that about two out of every five children ... from lower-income families and were of East Asian heritage. , The ...
(Date:7/25/2014)... A new study of participants in the National Lung ... in Cancer , found evidence that men and women ... abnormal finding on a lung cancer screening test did not ... those who were screened and found to be cancer-free. ... “We expected that participants with an abnormal finding would be ...
(Date:7/25/2014)... Tucson, AZ (PRWEB) July 25, 2014 ... Solutions , a Nuanced Media client and the ... medical and dental employee handbooks, announced their partnership ... , TransAct is a registered ISO/MSP of Chase ... in the transaction processing industry. Companies that are ...
(Date:7/25/2014)... TX (PRWEB) July 25, 2014 ... the current state of the Galactooligosaccharides (GOS) ... a basic overview of the industry, including definitions, ... and Chinese domestic market analysis are provided with ... landscape of the market. A comparison between the ...
(Date:7/25/2014)... Drexel University College of Medicine is ... has been appointed vice dean for education, effective October 1, ... Commonwealth Medical College, where she is currently chair of the ... professor of medicine. , As a member of the ... a major role in many aspects of the development of ...
Breaking Medicine News(10 mins):Health News:North York Dental Provides Services to Toronto Children in Light of Growing Demand 2Health News:North York Dental Provides Services to Toronto Children in Light of Growing Demand 3Health News:Full Explanation Reduces Seniors’ Worries about Lung Cancer Screening 2Health News:Full Explanation Reduces Seniors’ Worries about Lung Cancer Screening 3Health News:Full Explanation Reduces Seniors’ Worries about Lung Cancer Screening 4Health News:Full Explanation Reduces Seniors’ Worries about Lung Cancer Screening 5Health News:Nuanced Media Client, CEDR HR Solutions, Partners with TransAct to Serve Medical, Dental, and Eye Care Professionals 2Health News:GOS Market (Galacto-oligosaccharides) Development in Global & China Regions Now Available at DeepResearchReports.com 2Health News:GOS Market (Galacto-oligosaccharides) Development in Global & China Regions Now Available at DeepResearchReports.com 3Health News:Valerie D. Weber, MD, Appointed Vice Dean for Education at Drexel University College of Medicine 2Health News:Valerie D. Weber, MD, Appointed Vice Dean for Education at Drexel University College of Medicine 3
... more unclimbed ... mountains to challenge., SEATTLE, June 23 Late on Saturday, ... that they,had reached the safe limits of their attempt to climb one ... rock to,move within 500 vertical feet of the summit of Peak 8290 ...
... Educational Activities Beyond the Call ... ... The American Dental,Hygienists, Association and Johnson & Johnson Healthcare Products ... Recognition Program designed to salute dental hygienists,outstanding commitment to promote oral ...
... , - European Health Ministers Meet to Focus on ... Expected to be Signed, It has long been accepted ... does the reverse apply? Does greater health lead,to greater wealth, ... week (25-27 June), ministers of health, international experts, and,over 500 ...
... An Open Letter to Barack Obama, LOUISVILLE, Ky., ... Obama was published in Sunday,s Chicago Tribune., "Quitting ... Dear Sen. Obama, I viewed with great ... As a professor of medicine with a long-term research,program ...
... Ariz., June 23 Inspired by last year,s "Live,Your Best ... Oprah Magazine,Miraval will continue the legacy of giving back by ... a spa vacation. Through a contest,people all across the country ... spa vacation. The selected winners will enjoy a four-day,three-night retreat ...
... Emile Hirsch joined,with international agency Oxfam to raise ... Republic of Congo. Emile spent five,days visiting the ... deadly,conflicts since World War II, where over 5.4 ... violence and rape are a daily threat., ...
Cached Medicine News:Health News:Big Expedition Ends Peak 8290 Attempt 500 Feet From the Summit 2Health News:Big Expedition Ends Peak 8290 Attempt 500 Feet From the Summit 3Health News:Big Expedition Ends Peak 8290 Attempt 500 Feet From the Summit 4Health News:Big Expedition Ends Peak 8290 Attempt 500 Feet From the Summit 5Health News:American Dental Hygienists' Association and Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc. Unveil Honorees of Inaugural HYGIENIST HERO(TM) Recognition Program 2Health News:American Dental Hygienists' Association and Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc. Unveil Honorees of Inaugural HYGIENIST HERO(TM) Recognition Program 3Health News:American Dental Hygienists' Association and Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc. Unveil Honorees of Inaugural HYGIENIST HERO(TM) Recognition Program 4Health News:American Dental Hygienists' Association and Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc. Unveil Honorees of Inaugural HYGIENIST HERO(TM) Recognition Program 5Health News:Does Better Health Lead to Better Wealth? 2Health News:Does Better Health Lead to Better Wealth? 3Health News:'Quitting Isn't That Easy' 2Health News:'Quitting Isn't That Easy' 3Health News:Miraval Tucson to Continue Legacy of Awarding Spa Vacation 2Health News:Emile Hirsch Visits the Democratic Republic of Congo With International Aid Agency Oxfam 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: