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ThermoGenesis Announces MXP Involvement in New Regenerative Medicine Initiatives
Date:1/29/2009

PROGRAMS INCLUDE BONE MARROW CLINICAL TRIAL IN ITALY

RANCHO CORDOVA, Calif., Jan. 29 /PRNewswire-FirstCall/ -- ThermoGenesis Corp. (Nasdaq: KOOL), a leading supplier of innovative products and services that process and store adult stem cells, said today that its MarrowXpress(TM) (MXP(TM)) device is now being used in two new regenerative medicine programs.

These efforts include use of the MXP, which is used to concentrate stem cells from bone marrow, in an ongoing Phase II clinical trial being conducted at the University of Naples in Italy to study the effect of bone marrow derived mononuclear cells on patients with critical limb ischemia (CLI). In addition, ThermoGenesis announced the launch of its distribution agreement with Celling Technologies, an orthopedics company focusing on the cell therapy market.

The University of Naples trial will involve 30 patients and include 12-month follow-up to determine the impact of the treatment. The lead investigators are Dr. Gilda Cobellis and Professor Vincenzo Sica, who has been treating CLI patients with mononuclear cells derived from bone marrow for several years. The early results from his efforts indicate the treatment has resulted in significant improvement in patients' clinical status. The trial in Naples represents the first human use of the ThermoGenesis MXP System for the treatment of CLI patients.

Within one year of being diagnosed with CLI, 40-50 percent of the more than 20 million patients suffering from diabetes in the U.S. will experience a major amputation. The utility of bone marrow derived stem cells to prevent amputation by restoring blood flow to the affected limb is being studied in a number of clinical settings.

"We are pleased that our new MXP System has been selected for this CLI trial with the University of Naples,
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SOURCE ThermoGenesis Corp.
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