Navigation Links
TheraVasc Releases Phase I Trial Data Demonstrating Safety of Drug in Diabetic Patients
Date:9/20/2011

CLEVELAND, Sept. 20, 2011 /PRNewswire/ -- TheraVasc (www.theravasc.com) announced the successful completion of a Phase I clinical trial of a drug, TV1001, to diabetic patients. The trial included 12 diabetic patients who each received a single dose of two different oral formulations of TV1001, an enteric coated and a non-enteric coated capsule, to determine safety and blood levels of the drug.  Based on prior studies conducted in animals, the circulating blood levels in all patients were in the range believed to be therapeutic.

"Many of the patients treated in this study have severe chronic wounds for which no effective treatments are available. Based on the safety of the drug we observed in this study and the ability to achieve a therapeutic benefit in animals at the dose tested in this study, this drug offers hope that someday we might have a way of effectively treating these diabetic ulcers," said Dr. Frank Greenway, the Principal Investigator of the Study and Director of the Outpatient Clinic at the Pennington Biomedical Research Center.

Few adverse events were reported during the trials and there was no significant increase in methemoglobin levels, which would have prevented the release of oxygen in the blood, at the dose tested, the most likely adverse event associated with the treatment.  

TheraVasc's previously conducted animal studies using TV1001 showed that when taken chronically, similar blood levels resulted in the generation of new blood vessels in oxygen-deprived limbs, improvement in wound healing, and inhibition of tissue necrosis. The company expects to complete Phase IIa trials in mid-2012 in which the safety of multiple doses of chronically administered TV1001 will be assessed, along with testing for evidence of biological activity.

TheraVasc is initially developing TV1001 as a treatment for diabetic patients with Peripheral Arterial Disease (PAD), a condition affec
'/>"/>

SOURCE TheraVasc Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Sarasotas Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes
2. CEL-SCI Corporation Releases Letter to Shareholders
3. AcroMetrix Releases New OptiQuant(R) HIV-1 Quantification Panel
4. Cardinal Health Releases New Tool to Combat MRSA Infections in Hospitals
5. Immunosyn Corporation Releases SF-1019 Study Results
6. TCS Healthcare Technologies Releases Three New Clinical Care Programs Within ACUITY
7. Immunosyn Releases Wound Healing Photographs From the First Phase Proof of Concept Trial in Europe for Treatment of Diabetic Ulcers With Biopharmeceutical SF-1019
8. QRxPharma Releases Successful Phase 3 Study Results for Dual Opioid Pain Therapy
9. CenterWatch Releases State of the Clinical Trials Industry 2008 - A Key Industry Resource for Market Research and Competitive Intelligence
10. QRxPharma Releases Additional Phase 3 Data for Q8003IR Dual Opioid Pain Therapy
11. Genaera Releases Phase 1 Data and New Preclinical Data on the CNS Function of Trodusquemine (MSI-1436) at CBI Obesity Summit
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2015)...  This industry report package offers the most up-to-date market data on ... the world and in the top 10 global countries. Along with a ... following countries: Australia , China ... Italy , Japan , ... , United States The reports ...
(Date:3/3/2015)... PARK, Calif. , March 3, 2015  BioPharmX ... the development of novel drug delivery products to address ... announced that Jim Pekarsky , chief executive officer ... th Annual Roth Capital Partners Conference on Wednesday, ... Laguna Niguel in ...
(Date:3/3/2015)... DUBLIN , Mar. 03, 2015 Research and ... addition of the "Global POC Diagnostics Market 2015-2019" ... The analysts forecast the Global POC Diagnostics market to ... period 2014-2019. POC diagnostics are IVD ... outside a clinical laboratory setting. The use of these ...
Breaking Medicine Technology:Global Safety Glass Market to 2019 - Market Size, Top 10 Countries, Trends, and Forecasts 2BioPharmX Corporation To Present At 27th Annual Roth Capital Partners Conference On March 11, 2015 2BioPharmX Corporation To Present At 27th Annual Roth Capital Partners Conference On March 11, 2015 3Global POC Diagnostics Market 2015-2019 with Abbott Labs, Alere, Bayer Healthcare, Danaher, F. Hoffmann-La Roche & Johnson & Johnson Dominating 2
... Wis., Sept. 16 Top researchers at the Gastrointestinal ... Dallas are exploring the clinical applications of BCM-95®, a ... bioavailability. Previous studies have shown that ... forms of curcumin, and had a retention time in ...
... Mich., Sept. 16 Metabolic Solutions Development Company (MSDC), ... Association for the Study of Diabetes (EASD) annual conference ... indicates that the company,s clinical candidate, MSDC-0160, promotes the ... to the creation of more brown fat.  The research ...
Cached Medicine Technology:BCM-95 Demonstrates Superior Anti-Inflammatory Effects 2Metabolic Solutions Development Company to Present Research Findings to European Association for the Study of Diabetes 2
(Date:3/3/2015)... (PRWEB) March 03, 2015 The ... public’s expectation of excellence in care and safe practice ... position of the RNS that biologic infusions are administered ... the direct supervision of a registered nurse (RN), as ... including anaphylaxis can occur in patients receiving these medications ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 The human ... of the augmentation market. The wearable augmentation sector is ... of size in the upcoming years. , The ... owing to a big number of new products launches ... American region, high technological advancements as well as the ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 US Air ... efficiency air purification systems, is pleased to announce that all ... brief supply interruption related to the west coast port strikes. ... just around the corner. , The port ... expected to slow fourth quarter economic growth by as much ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 The first ... the National Sleep Foundation. The event brings recognition to ... over. , According to the Centers for ... problems of one form or another. Too little or ... risk of physical illness and depression, and even a ...
(Date:3/3/2015)... 2015 Today is International Ear Care ... the occasion to applaud and promote the launch of ... Health Organization (WHO) for stemming the threat of noise-induced ... young people to practice safe listening when they recreate, ... or sporting events, or engaging in other forms of ...
Breaking Medicine News(10 mins):Health News:Administration of Biologic Infusions: A Position Statement of the Rheumatology Nurses Society 2Health News:Human Augmentation Market to Pose 43.5% CAGR Through 2020, States MarketsandMarkets in its New Research Study Now Available at MarketPublishers.com 2Health News:Rabbit Air Purifiers Back In Stock at US Air Purifiers LLC 2Health News:Rabbit Air Purifiers Back In Stock at US Air Purifiers LLC 3Health News:Medicationdiscountcard.com recognizes sleep awareness week with discounts on sleep meds including Ambien, Lunesta, and Sonata 2Health News:Medicationdiscountcard.com recognizes sleep awareness week with discounts on sleep meds including Ambien, Lunesta, and Sonata 3Health News:ASHA Applauds Launch of New WHO Campaign 2
... Unitrin Direct, an,auto insurance company that has become ... coverage with outstanding personal,service, has implemented a new ... is dramatically reducing the time customers spend on,the ... have to hold if a Unitrin Direct,representative isn,t ...
... issue of the Journal of Periodontology (JOP) found that smokers ... than non-smokers. , The study followed 10 smokers and 10 ... smoke on the long term outcomes of a treatment to ... teeth. After two years, residual gum recession around the ...
... BUFFALO, N.Y. -- "We are the bouncers, the bodyguards, the ... organizers, the managers and leaders for the patient ... Often ... event. See us, hear us, feel us.", Welcome to the ... This telling reflection on the profession appears in a paper ...
... health, blood pressure and quality of life improve ... News) -- Undergoing dialysis at home most nights ... kidney patients, health than conventional three-times-a-week dialysis, new ... comparing frequent nocturnal dialysis to standard dialysis therapy, ...
... years experience in vendor, provider and consulting ... ATLANTA, Sept. 18 Health Level Seven (HL7), ... representation, today announced the appointment of John Quinn,as ... reached an,agreement in principle and Quinn, who is ...
... MR Now Available for All Three Major MR ... Scanner ... of the 3.0T Prostate eCoil (TM) MR Endorectal Coil compatible,with magnetic ... prostate eCoil for GE scanners in 2006. (Logo: http://www.newscom.com/cgi-bin/prnh/20040309/MEDRADLOGO ...
Cached Medicine News:Health News:New Technology at Unitrin Direct Gives Customers an Alternative to Waiting 2Health News:New Technology at Unitrin Direct Gives Customers an Alternative to Waiting 3Health News:Nurses describe dedication, frustration associated with their jobs 2Health News:Nurses describe dedication, frustration associated with their jobs 3Health News:Nighttime Home Dialysis a Boon for Kidney Patients 2Health News:Nighttime Home Dialysis a Boon for Kidney Patients 3Health News:Health Level Seven Appoints John Quinn as CTO 2Health News:Health Level Seven Appoints John Quinn as CTO 3Health News:MEDRAD Announces eCoil(TM) for Siemens, Philips 3.0T MR Scanners 2Health News:MEDRAD Announces eCoil(TM) for Siemens, Philips 3.0T MR Scanners 3
... super series slit lamp ... viewing of the posterior ... diagnostic capability, specifically addressing ... view, fundus image resolution ...
Volk indirect lenses. Standard BIO examinations....
... the "Super 90". Volk's SuperField has become ... for today's discriminating practitioner. Its ideal .76x ... it perfect as the primary high resolution ... has been specifically designed for increased working ...
Precision has its new line of programmable autoclaves which are easy to use bench-top autoclaves or models to fit any need. It has 4 adjustable sterilization programs, touch button control panel, man...
Medicine Products: