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The Zacks Analyst Blog Highlights: Anthera Pharmaceuticals, Amgen, Eli Lilly, Actelion and InterMune
Date:7/21/2014

from IPF in the U.S. Results from the study showed that treatment with Esbriet significantly reduced IPF disease progression at week 52, thus meeting its primary objective.

Esbriet also demonstrated significant treatment effects in the six-minute walk test distance change and progression-free survival. Moreover, the drug demonstrated favorable safety and tolerability profiles.

Esbriet is already approved and available in several EU countries including Germany, France, Italy and the UK among others. The drug is also approved in countries like Canada, Japan, China, India, Argentina and Mexico. The company recorded Esbriet sales of $30.3 million in the first quarter of 2014. Esbriet sales in 2014 are expected in the range of $130 million to $140 million.

Though Esbriet is the only approved medicine for IPF, several companies are developing their candidates to tap the IPF market. The nearest threat for InterMune is from Boehringer Ingelheim's IPF candidate nintedanib, which was filed in the U.S. in Jul 2014. Nintedanib was also granted a breakthrough therapy designation by the FDA earlier in the month. Nintedanib is under review in the EU as well.

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