Navigation Links
The Use of New Replikins Synthetic Vaccines to Prevent Pandemics to be Presented at Influenza Congress Nov. 12 in Washington DC
Date:11/6/2012

ze current Replikins synthetic TransFlu™(including H5N1) vaccine. The data suggests that any vaccines, which might be active against H5N1, should be produced and tested as soon as possible.

Methods

The methods have been detailed in references 1-4. All 4,588 HA gene sequences and 3,163 p B1 gene sequences reported in the Pubmed data base from 2003 to 2011 were analyzed for Replikin peptides.

Results

HA Gene

The Figure shows that in 2001, bird and human H5N1 virus HA genes, had a high concentration or Replikin Count (greater than 4.0 Replikins per 100 amino acids) (Replikin Count=number of Replikins per 100 amino acids) which comprised 60% of the Replikins of the total H5N1 population. Low Counts (4.0 and below) are associated with 'resting' non-outbreak states of the virus (4). This concentration decreased after 2001 to only 20% in 2009. Then in 2010, more H5N1 HA genes had higher Replikin Counts. By 2011, H5N1 HA genes with Replikin Counts greater than 4.0 now have been found to comprise 82% of the total H5N1 population, the highest such concentration ever found.

p B1 Gene

Similarly, the Figure shows that the p B1 gene 'high' Replikin Count increased almost four-fold from 2001 to 2010, two-fold from 2009 to 2010, and peaked one year before outbreaks in Cambodia and Vietnam. In influenza, increasing Replikin Counts at p<0.001 have been followed by an outbreak in seven of seven previous Replikins prediction trials, including two for H5N1 (4).

In addition, not shown separately in the Figure, in 2011, human H5N1 Mean Replikin Counts also peaked; HA Mean Counts were 4.9(+/-0.8), and p B1 Mean Counts  12.7(+/-15.1).

The following pattern has now repeatedly been observed: genomic Replikin Counts increase to high levels, accompanied by sporadic lethal human cases, as recently seen in Cambodia (1), followed by an outbreak of rapidly replicating spreading lethal human d
'/>"/>

SOURCE Replikins
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Inovio Pharmaceuticals Granted U.S. Patent Protection for Synthetic Vaccine for Cervical Dysplasia and Cancer
2. Synthetic Biologics Appoints Carol Reed, M.D., as Senior Vice President of Clinical & Regulatory Affairs
3. Synthetic Biologics Reports Second Quarter 2012 Financial Results
4. Synthetic Biologics Initiates Development of Monoclonal Antibodies for Treatment of Acinetobacter Infections
5. Global Human Vaccines Industry
6. Chinese Compulsory Immunization Program for Livestock Creates Massive Opportunity for Animal Vaccines and Biologics Developers
7. iBio Announces Important Expansion of its Intellectual Property Portfolio: Allowance of Patent for Anthrax Vaccines and Further Application of Modulator Platform
8. Global Veterinary Vaccines Industry
9. Whats Next In Vaccines (Malaria, Diabetes, Alzheimers, Allergies and 30 Other Targets in the 2012-2021 Vaccine Pipeline)
10. Whats New with Flu this Season: Industry Recommendations, New Vaccines and 100% Paperless Flu Program Solution
11. Sanofi Pasteur to add 2D barcode to six more vaccines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... Hampshire , und BARCELONA ... -- (Stand Nr. 4410) iCAD, Inc. (Nasdaq: ... von moderner Bildanalyse, Lösungen für Behandlungsabläufe und ... Krebserkrankungen, hat heute die sofortige Verfügbarkeit des ... Electronic Brachytherapy (eBx ® ) System ® ...
(Date:4/24/2015)... Today, humanity takes a massive step toward reaching our shared ... CONTACTS announces their new Apple Watch app which allows the ... Two taps. New contacts. From your watch. We live ... LensGauge which helps keep track of how long your lenses ... "Since our inception, we,ve been dedicated to providing our ...
(Date:4/24/2015)... , April 24, 2015   Bernstein ... Pharmaceuticals, Inc. ("Aerie" or the "Company") (NASDAQ: ... to investors in violation of the federal securities ... Aerie breached their fiduciary duties to shareholders. ... on the discovery, development and commercialization of first-in-class ...
Breaking Medicine Technology:Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 2Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 3Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 4Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 5Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 6Attention: We live in the future. Order contact lenses from your wrist with the 1-800 CONTACTS app for Apple Watch 2Bernstein Liebhard LLP Investigates Claims On Behalf Of Those Who Invested In Aerie Pharmaceuticals, Inc. 2
... YORK, Sept. 15, 2011 Close to 100 openly HIV-positive ... around the world have signed a new letter ( http://tinyurl.com/pozPrEPletter ... than on fear or misinformation," of the challenges and opportunities ... and bisexual men and transgender women. The new open letter ...
... Qualitest Pharmaceuticals today issued a voluntary, nationwide, retail-level ... is being implemented because of a packaging error, where ... reversing the weekly tablet orientation and making the lot ... error and the potential for this error to have ...
Cached Medicine Technology:Open Letter From HIV-Positive Prevention Advocates Rejects Misinformation About Pre-Exposure Prophylaxis (PrEP) 2Open Letter From HIV-Positive Prevention Advocates Rejects Misinformation About Pre-Exposure Prophylaxis (PrEP) 3Qualitest Pharmaceuticals Issues a Nationwide Voluntary Recall of Oral Contraceptives 2
(Date:4/25/2015)... Islands, BWI (PRWEB) April 25, 2015 ... has celebrated three months of successfully welcoming visitors to ... 5, 2015. , As part of a major ... Providenciales airport was completely redesigned to speed up arrivals. ... the process of getting out of the airport and ...
(Date:4/25/2015)... Illinois (PRWEB) April 25, 2015 ... enrichment and wellness, management and operations, and sales ... Meeting and Exhibition scheduled to be held from ... , LeadingAge Illinois is the largest eldercare association ... providers of services for older adults, including senior ...
(Date:4/25/2015)... (PRWEB) April 25, 2015 Parker and Sons ... and cooling, has spiked in Arizona alongside the growing economy. ... additional forty employees for April to help account for the ... forty employees in April is something we are enthusiastic about. ... said Paul Kelly, president at Parker and Sons. , Indeed, ...
(Date:4/25/2015)... April 25, 2015 The URO CENTER of ... has been chosen by the New York Academy of Medicine ... medicine in the field of Urology. , Dr. Ferdinand Valentine, ... speciality, Genito-Urinary diseases. He was a man of rare ... of urology. Not only did he devote his life ...
(Date:4/25/2015)... April 25, 2015 Sports controversies continue to revolve ... confines, as was the case with the Miami Dolphins and Richie ... seen in the Ray Rice domestic abuse case. In a recent ... News discusses the implications of locker room culture on teams. ... what other teams should do to improve the locker room as ...
Breaking Medicine News(10 mins):Health News:The Tuscany on Grace Bay Celebrates Providenciales Airport Expansion With Summer Specials to Travelers! 2Health News:Gardant Management Solutions Staff Shares Operational Expertise 2Health News:Parker and Sons Plans to Expand in 2015 2Health News:The 2015 Valentine Award Comes From The Heart and Goes To Famous New York Urologist 2Health News:The 2015 Valentine Award Comes From The Heart and Goes To Famous New York Urologist 3Health News:David Steele Discusses Locker Room Culture on SCI TV 2Health News:David Steele Discusses Locker Room Culture on SCI TV 3
... Danaher Corporation,(NYSE: DHR ) announced that Executive ... will be presenting at the Goldman Sachs Global,Industrials ... 5, 2008 at,8:00 a.m. EST. The audio will ... Danaher Corporation is a leading manufacturer of Professional,Instrumentation, ...
... leaving ,hard-core, group behind, experts say , , TUESDAY, ... current smokers trying to kick the habit are now ... study finds. , In fact, nicotine dependence has risen ... of highly nicotine-dependent people has gone up 32 percent, ...
... 28 Nationwide,Health Properties, Inc. (NYSE: NHP ) ... per share dividend on our common stock that will,be ... on November 14, 2008., In addition, our Board ... Series B cumulative convertible preferred stock that will,be paid ...
... Vessels, Healthy ... Ability to Relax, ST. LOUIS, Oct. ... may enhance the function of arteries,in stroke patients, and help all Americans ... disease is the,nation,s number one killer while stroke is the third leading ...
... WellSpring Pharmaceutical,Corporation, a growing North American-based pharmaceutical ... Chief Operating Officer.,Formerly, Ms. Shusko held the position ... early 2000. In her new role as COO, ... areas of oversight,to operations with an initial focus ...
... help consumers get,accurate, dependable information about healthcare ... support consumer,engagement and improved quality in healthcare, ... consumer-focused, internet-based public,reporting. These guidelines will assist ... in an evidence-based and,consumer-friendly format that can ...
Cached Medicine News:Health News:Today's Smokers More Addicted to Nicotine 2Health News:Today's Smokers More Addicted to Nicotine 3Health News:NHP Declares Quarterly Cash Dividends on Common Stock and Series B Preferred Stock 2Health News:NHP Declares Quarterly Cash Dividends on Common Stock and Series B Preferred Stock 3Health News:Study Shows How Soy Compound Lowers Blood Pressure and Stroke Risk 2Health News:WellSpring Pharmaceutical Corp. Names Wendy Shusko as New Chief Operating Officer 2Health News:NQF Endorses Guidelines for Consumer-Focused Public Reporting 2Health News:NQF Endorses Guidelines for Consumer-Focused Public Reporting 3Health News:NQF Endorses Guidelines for Consumer-Focused Public Reporting 4Health News:NQF Endorses Guidelines for Consumer-Focused Public Reporting 5
Open ring design for globe fixation during various ocular procedures. Blunt fixation points. Swivel handle provides increased flexibility. Manufactured in titanium....
Corneal fixation ring with broad teeth. Notches on anterior surface for guiding cardinal suture placement....
Adult size. Loops retract lids. Polished finish....
...
Medicine Products: