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The Use of New Replikins Synthetic Vaccines to Prevent Pandemics to be Presented at Influenza Congress Nov. 12 in Washington DC
Date:11/6/2012

LONDON, Nov. 6, 2012 /PRNewswire/ -- In the lead paper to be presented at the Influenza Congress USA in Washington DC on November 12, 2012, Dr. Samuel Bogoch of Bioradar UK Ltd. will discuss how new synthetic Replikin vaccines may prevent the development of influenza virus outbreaks and pandemics. Pandemic prevention, not previously possible, is being considered for the first time because quantitative changes in Replikins® in the virus genome have been shown to predict strain-specific outbreaks and the particular geographic locations where outbreaks will occur (1-5).       

(Photo: http://photos.prnewswire.com/prnh/20121106/PH07162-INFO )           

The H1N1 pandemic of 2009 was predicted one year in advance by observing an increased Replikin®Count. Currently, the human lethality rate of H5N1 has increased to its highest level ever, as predicted by the increasing Replikin®Count of the p B1 'Lethality' Gene (1) as well as clinically (Figure).

The H5N1 virus previously has not been very infectious and has not spread easily to humans. (WHO total of 566 human cases since 2003.) However, in 2010, the Replikin®Count of the HA 'Infectivity' gene of H5N1 increased (2) predicting the outbreaks which have occurred in Cambodia and Vietnam in 2011-12 (1). In 2011 the Count has increased further to its highest level since the discovery of H5N1 in 1959 (p<0.001) (Figure).

Thus the risk of further H5N1 outbreaks, and in a more infectious and more lethal form, appears also to have increased in view of the demonstrated relationship of rising genomic Replikin®Counts to clinical outbreaks (1-5). This information is being used to synthesi
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