Navigation Links
The Medicines Company's Cangrelor - Is it better than Plavix for Acute Coronary Syndrome?
Date:11/26/2013

DUBLIN, Nov. 26, 2013 /PRNewswire/ --Research and Markets (http://www.researchandmarkets.com/research/h45rfk/the_medicines) has announced the addition of the "The Medicines Company's Cangrelor - Is it better than Plavix for Acute Coronary Syndrome?" report to their offering.

(Logo: http://photos.prnewswire.com/prnh/20130307/600769)

Cangrelor is a reversible, intravenous inhibitor of the P2Y12 receptor whose effect is to inhibit adenosine diphosphate-induced platelet aggregation. The Medicines Company is developing it for use in the setting of patients undergoing percutaneous coronary intervention procedures (PCI), specifically those who have not used Plavix or other P2Y12 inhibitors in the prior week. Two previous phase III trials failed to meet their primary endpoints. Thus, approval hangs on the results of a third trial, CHAMPION-PHOENIX that should report before year-end. This report explores the probability of a favorable phase III outcome, eventual approval, and the market opportunity.

Key Topics Covered:

INTRODUCTION

1. Acute coronary syndromes (ACS)

2. Thrombosis is at the center of causality

3. Clinicians use several approaches to platelet inhibition


CANGRELOR

1. Phase I/II trials

2. Pivotal trials


CLINICAL AND REGULATORY DISCUSSION

1. Why did CHAMPION-PCI and CHAMPION-PLATFORM fail?

2. Given the PCI and PLATFORM results, what are the lessons for PHOENIX?

3. Are there meaningful safety concerns associated with cangrelor?

4. Are there any bleeding concerns?

5. Possible adverse pulmonary effects of cangrelor

6. What are the regulatory issues that cangrelor will face?

7. Other relevant FDA guidance

8. In summary

MARKET OPPORTUNITY

1. Overview of issues

2. Market estimates

3. Pipeline products

Companies Mentioned

  • Eli Lilly,
  • Bristol Myers Squibb,
  • Astra Zeneca

For more information visit http://www.researchandmarkets.com/research/h45rfk/the_medicines

About Research and Markets
Research and Markets is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.

Media Contact:

Laura Wood , +353-1-481-1716, press@researchandmarkets.net




'/>"/>
SOURCE Research and Markets
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Worlds Only USDA Certified Organic and FDA Registered Homeopathic Medicines Guaranteed to Work
2. Lilly Expands Strategic Partnership with Chinese Manufacturer Novast to Serve Chinese Patients with High-Quality Branded Generic Medicines
3. Warning: Not All Cold Sore Medicines Are Created Equal
4. Kick Off Summer Vacation With Five Simple Tips to Safely Store Medicines While Traveling
5. Global pharmaceutical industry calls for broad-based cooperation to fight online sales of counterfeit medicines around the world
6. Unigene Provides Update Following Recent EMA Recommendation on Calcitonin-Containing Medicines
7. New Research Reveals Extent of Poor-Quality Antimalarial Medicines in South American Countries
8. Watson Applauds GPhA Study Demonstrating $1 Trillion in Prescription Drug Savings from Generic Medicines
9. Sigma-taus Antimalarial Awarded "Project of the Year" 2011 by Medicines for Malaria Venture
10. National Community Pharmacists Association and Purdue Pharma Urge Americans to Safeguard Rx Medicines This Holiday Season
11. PTC Therapeutics Announces European Medicines Agency Validation of Marketing Authorization Application for Ataluren in Duchenne Muscular Dystrophy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2019)... Colo. (PRWEB) , ... August 21, 2019 , ... ... improving patron experience by lowering pool chemical use with Clear Comfort’s Advanced Oxidation ... is able to save significant chemical expense dollars, simplify its water care protocol ...
(Date:8/19/2019)... ... August 19, 2019 , ... ... their 2nd Annual National Sports Summit, August 25-26 at the Hyatt Place in ... leaders from all major professional sports programs to discuss progress made over the ...
(Date:8/19/2019)... ... August 19, 2019 , ... ... today announced the findings of research validating the clinical impact of MedAware’s machine ... published 7 August 2019 in the Journal of American Medical Informatics Association ...
Breaking Medicine Technology:
(Date:8/16/2019)... ... August 16, 2019 , ... Tim ... throughout the Mid-Atlantic and North East at the 2019 Safety Academy sponsored through ... build on existing construction safety concepts and define not only a safety program ...
(Date:8/15/2019)... ... August 15, 2019 , ... ... annual Inc. 5000 list, the most prestigious ranking of the nation’s fastest-growing private ... the American economy’s most dynamic segment—its independent small businesses. Microsoft, Dell, Domino’s Pizza, ...
(Date:8/15/2019)... ... August 15, 2019 , ... With many students either starting college for the first time, ... demographic. According to the CDC , “there are about 20 million new cases of ... between the ages of 15 and 24. Young people are at greater risk of getting ...
(Date:8/15/2019)... ... August 15, 2019 , ... Heritage Woods of Rockford Administrator Jaclyn ... Living (NCAL). , This award is part of the NCAL Awards Program, which recognizes ... “The common element among this year’s recipients is that they all go out of ...
(Date:8/14/2019)... Colo. (PRWEB) , ... August 14, 2019 , ... Inc. ... #2008 on its annual Inc. 5000 list, the most prestigious ranking of the nation’s ... #41 among Colorado based companies and #153 in the Health sector. The list represents ...
Breaking Medicine News(10 mins):