Navigation Links
The Leukemia & Lymphoma Society and Memgen Collaborate on CLL Clinical Trial
Date:6/18/2008

WHITE PLAINS, N.Y., June 18 /PRNewswire/ -- The Leukemia & Lymphoma Society (LLS) and Memgen jointly announced an agreement today to collaborate on a new Phase I clinical trial. The trial will use Memgen's ISF35, an active immunotherapy approach for treating chronic lymphocytic leukemia (CLL).

Based on its alliance with LLS, Memgen plans to begin a Phase I clinical trial this year for up to 12 patients who have 17p-, refractory or resistant CLL with limited therapeutic options. Patients will receive three infusions of ISF35, followed by up to three courses of FCR (fludarabine, cyclophosphamide and rituximab). After treatment, the patients will be followed for at least one year to determine the safety and efficacy of the regimen.

Charles Prussak, Ph.D., Pharm.D., one of the founders of Memgen, said, "Memgen is very pleased to be working with The Leukemia & Lymphoma Society. ISF35 has the potential to become a cornerstone in treatments for leukemia and perhaps for lymphoma. In the initial Phase I CLL clinical trial of ISF35, conducted by William Wierda, M.D., Ph.D., at The University of Texas M. D. Anderson Cancer Center, a single infusion of ISF35 resulted in the rapid decline in circulating and lymph node bound leukemic cells, induced long-term immune based responses against these cells and sensitized them to standard chemotherapies, even in several patients with drug resistant disease."

In commenting on Memgen's upcoming clinical trial, Louis J. DeGennaro, Ph.D., LLS's chief scientific officer, said, "There is a clear unmet medical need for new therapies to treat refractory or relapsed CLL, in particular the 17p- patients. Many of these patients do not respond to current conventional therapy and their treatment options are severely limited. Our goal is to bring new treatment options to these patients more quickly. The partnership with Memgen accelerates the clinical testing of an immunotherapy and brings us closer to that goal."

T
'/>"/>

SOURCE The Leukemia & Lymphoma Society
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Xenomics Announces Implementation of its First Diagnostic Test for Acute Myeloid Leukemia Into Clinical Practice
2. CuraGen and TopoTarget Initiate Phase I/II Clinical Trial of Belinostat (PXD101) Combination Therapy for Acute Myeloid Leukemia
3. St. Jude Discovers Factors That Accelerate Resistance to Gleevec(TM) Targeted Therapy in Lymphoblastic Leukemia
4. September is Leukemia, Lymphoma and Myeloma Awareness Month
5. The Leukemia & Lymphoma Society is Encouraged by Promising News for Myeloma Patients
6. The Leukemia & Lymphoma Society and Cleveland Clinic Taussig Cancer Institute Announce Groundbreaking Partnership to Accelerate Drug Approvals
7. Leukemia Drug Proves Safe and Effective Over the Long Term
8. TREANDA Significantly Improves Clinical Outcomes in Patients with Chronic Lymphocytic Leukemia Compared to Chlorambucil
9. Preclinical Studies Show Promise for Novel Antibody Therapy to Treat Acute Myeloid Leukemia (AML)
10. Celator(R) Pharmaceuticals Reports CPX-351 Shows Anti-Cancer Activity in Leukemia Patients
11. Data Presented at 2007 ASH Meeting Demonstrate Activity of Forodesine HCl as a Single Agent or in Combination With Bendamustine in Certain Types of Leukemia and Lymphoma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... VALLEY, Pa. , July 28, 2014  Air ... reliable, uninterrupted supply of medical oxygen is vital to ... to technical innovations that not only improve the efficiency ... use. Air Products will highlight these systems—including systems for ... that reduce oxygen loss—from August 4-5 at the ...
(Date:7/28/2014)... BOULDER, Colo. , July 28, 2014 ... report financial results for the fourth quarter ... hold a conference call to discuss those ... Squarer, Chief Executive Officer and Michael ... the call.Conference Call InformationDate:Tuesday, August 12, 2014Time:9:00 ...
(Date:7/28/2014)... , July 28, 2014  Houston dentist ... he offers orthodontic treatment with Invisalign. With access ... can have their teeth straightened without feeling self-conscious ... benefits associated with other types of braces, but ... looks in addition to better support for their ...
Breaking Medicine Technology:Air Products Highlights Its Medical Oxygen Supply Systems for Emergency Oxygen Supply and Reduced Oxygen Loss at ASHE 2Air Products Highlights Its Medical Oxygen Supply Systems for Emergency Oxygen Supply and Reduced Oxygen Loss at ASHE 3Houston Cosmetic Dentist, Dr. Behzad Nazari, Now Offers Orthodontic Treatment with Invisalign 2
(Date:7/28/2014)... 2014 The “Tissue Diagnostics ... Digital pathology & Workflow, Special Staining), Disease ... Non Small Cell Lung Cancer and Others), ... companies, Research Laboratories, Contract Research Organizations and ... BRIC, Japan & RoW) - Trends & ...
(Date:7/28/2014)... “China Surgical Generators Market Outlook ... China Surgical Generators market. The report provides value, ... and average prices (in US dollars) within market ... and Argon Plasma Coagulation Generators. , The report ... for each of these market categories, and global ...
(Date:7/28/2014)... 28, 2014 Camp Soaring Eagle ... camp property in Cornville, AZ. The nonprofit organization, ... with the opportunity to attend medically supervised camps ... The organization offers a variety of programs to ... and life threatening illnesses including: Illness Specific Camping ...
(Date:7/28/2014)... Heights, MI (PRWEB) July 28, 2014 ... UHY, introduces the latest edition of UHY International Business ... provided by our members, on the most current business ... around the world. Issue 29 covers the following topics:, ... growth: Which industry sectors will thrive over the next ...
(Date:7/28/2014)... An estimated 68,000 women and men in the ... cancers – an aggressive form of the disease that ... of the body, such as the lungs, liver, bones, ... of Medicine have developed a compound directed at ... blocking tumor cells from “re-seeding.” Their discovery has been ...
Breaking Medicine News(10 mins):Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 2Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 3Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 4Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 5Health News:Key Market Data on China Surgical Generators Market to 2020 Report Available at MarketOptimizer.org 2Health News:Key Market Data on China Surgical Generators Market to 2020 Report Available at MarketOptimizer.org 3Health News:Key Market Data on China Surgical Generators Market to 2020 Report Available at MarketOptimizer.org 4Health News:Camp Soaring Eagle Announces New Camp Site 2Health News:Camp Soaring Eagle Announces New Camp Site 3Health News:Uhy International Business Issue 29 Now Available 2Health News:Uhy International Business Issue 29 Now Available 3Health News:Drexel Scientists Develop Compound to Stop Spread of Metastatic Cancer Cells 2Health News:Drexel Scientists Develop Compound to Stop Spread of Metastatic Cancer Cells 3
... the proposal of the Ministry of Health to hike the ... ,"A committee has been set up to review fees charged ... medical sector. This includes the licensing and renewal of licenses ... the medical or health establishments as well," said Dr Ibrahim ...
... Ahmedabad. A man suspected with avian influenza infection ... ,Qadar Abubhai Marghiwala, a 30-year-old resident of ... fever for a week., ,Gujarat's Health Minister ... as primary investigations revealed negative results., ,According ...
... taboo with a study on the mounting violence against women. ... supported with funds from the United Nations Development Fund for ... beaten -- usually by her husband or father. A campaign ... ,In Syria violence against women is usually from ...
... to six times as much sunlight as those with fair ... a new study// . ,Researchers at the Australian ... in the summer sunshine to produce enough Vitamin D whereas ... ,Acceptable levels of sunbathing also depends on geography ...
... people as young as 16 whereas the phenomenon once occurred only ... can escape stress in modern day life. Stress increases glucocorticoid levels. ... hair," Mumbai-based Sonal Shah said. ,"Initially, we used to ... to as low as 16 and 18," Shah told IANS on ...
... A new species that provides the missing evolutionary link between ... onto the land about 375 million years ago//, has been ... a skull, a neck, ribs and parts of the limbs ... ,These fossils, found on Ellesmere Island in Arctic ...
Cached Medicine News:Health News:Stress Can Cause Hair loss at 16 2Health News:Species Linking Fish And Land Animals Found 2Health News:Species Linking Fish And Land Animals Found 3
Straight 6 mm platform. McPherson handle. Manufactured in titanium. Overall length 3.3 inches....
Curved shafts and tips with 6.5 mm tying platform. Flat serrated handle with dull finish. Overall length 4.0 inches....
Angled shafts with 4 mm tying patform. Serrated handle with dull finish. Most popular size or model. Overall length 3.2 inches....
Ultra-fine 5 mm tying platform is valuable when manipulating delicate 10-0 and 11-0 sutures. Pin in handle keeps tips in alignment. Shafts available straight or angled 45 degrees, 8 mm from tip. Stra...
Medicine Products: