Navigation Links
The Leukemia & Lymphoma Society and Memgen Announce New Chronic Lymphocytic Leukemia Clinical Trial
Date:12/3/2008

WHITE PLAINS, N.Y., Dec. 3 /PRNewswire/ -- The Leukemia & Lymphoma Society (LLS) and Memgen, LLC jointly announce the beginning of a new clinical trial of ISF35, a cancer vaccine, at the University of California, San Diego (UCSD).

LLS is collaborating on this trial in the hopes that it will speed the development and approval of a novel approach aimed at treating patients with fludarabine refractory and/or 17p deleted chronic lymphocytic leukemia (CLL).

Doctors at UCSD have already begun treating the first patient with ISF35. They plan to enroll up to twelve patients. These patients will receive a vaccine expressing an immune-boosting molecule, ISF35 (Immune Stimulatory Factor 35), followed by three courses of rituximab plus the chemotherapy drugs fludarabine and cyclophosphamide (FCR).

"This clinical study builds upon three previous trials already completed at M.D. Anderson and here at UCSD," said Januario E. Castro, M.D., assistant clinical professor at the UCSD School of Medicine and the Moores Cancer Center, who leads the work. "Those trials showed remarkable results for ISF35 in patients with high risk and treatment-resistant CLL. Most importantly, ISF35 was well-tolerated with only minimal side effects, reduced CLL cells and lymph nodes in nearly every patient, and when combined with chemotherapy produced complete or partial remissions in patients with 17p deleted CLL."

"There is a clear unmet medical need for new therapies to treat refractory or relapsed CLL, and in particular 17p- patients," said Louis J. DeGennaro, Ph.D., LLS's chief scientific officer. "Our goal is to bring new treatment options to these patients quickly."

For more information about participating in this clinical trial, contact Denise Darrah, at the Moores UCSD Cancer Center, 858-822-5375, or '/>"/>

SOURCE The Leukemia & Lymphoma Society
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Sunesis Announces New Data on Voreloxin for Acute Myeloid Leukemia To Be Presented at ASH
2. St. Jude Identifies Genomic Causes of a Certain Type of Leukemia Relapse
3. Sunesis Pharmaceuticals Presents Clinical Trial Data of Voreloxin in Patients with Acute Myeloid Leukemia and Ovarian Cancer at the Chemotherapy Foundation Symposium
4. Genmab and GlaxoSmithKline Announce Positive Top-Line Results in Ofatumumab Chronic Lymphocytic Leukemia Pivotal Study
5. University of Rochester Researcher Named Millennium Pharmaceuticals Career Development Scholar of The Leukemia & Lymphoma Society
6. The Leukemia & Lymphoma Society and Memgen Collaborate on CLL Clinical Trial
7. Sunesis Pharmaceuticals Presents Data from Clinical Trials of Voreloxin (formerly SNS-595) in Patients with Acute Myeloid Leukemia at the 13th Congress of the European Hematology Association
8. Exelixis Presents Clinical Data Supporting the Safety and Initial Clinical Activity of XL228 in Chronic and Acute Leukemia
9. Micromet and MedImmune Commence Treatment in Phase 2 Trial of BiTE Antibody Blinatumomab (MT103/MEDI-538) in Patients with Acute Lymphoblastic Leukemia
10. Vion Pharmaceuticals Announces Presentation of Interim Data from Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Acute Myelogenous Leukemia at the ASCO(R) Annual Meeting
11. Sunesis Pharmaceuticals to Present Interim Clinical Data From Voreloxin (Formerly SNS-595) Ovarian Cancer Trial at 44th ASCO Annual Meeting and Acute Myeloid Leukemia Trials at 13th EHA Congress
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2015)... Alexza Pharmaceuticals, Inc. (Nasdaq: ALXA ) ... 31, 2015.  The net loss and the loss from ... $13.0 million, respectively, compared to $10.7 million and $8.8 ... March 31, 2015, Alexza had consolidated cash, cash equivalents, ... "We continue to focus on ways in which ...
(Date:5/6/2015)... NEW YORK , May 6, 2015 /PRNewswire/ ... patient activation and patient-reported outcomes for chronic pain, ... report released by The Bravewell Collaborative ... by the Patients Receiving Integrative Medicine Interventions Effectiveness ... medicine. Using data from PRIMIER ...
(Date:5/6/2015)... , May 6, 2015 CVS Health (NYSE: CVS ... Baltimore locations that sustained heavy fire damage during ... in Baltimore over the past week or ... is ahead," said CVS Health President and CEO Larry Merlo ... path to better health. There is no better way that we ...
Breaking Medicine Technology:Alexza Reports 2015 First Quarter Financial Results 2Alexza Reports 2015 First Quarter Financial Results 3Alexza Reports 2015 First Quarter Financial Results 4Alexza Reports 2015 First Quarter Financial Results 5Alexza Reports 2015 First Quarter Financial Results 6Alexza Reports 2015 First Quarter Financial Results 7Alexza Reports 2015 First Quarter Financial Results 8Alexza Reports 2015 First Quarter Financial Results 9Alexza Reports 2015 First Quarter Financial Results 10Integrative Medicine has Positive Impact on Patient Activation, Chronic Pain, Depression 2CVS Health Announces it Will Rebuild Baltimore CVS/pharmacy Locations 2
(Date:5/6/2015)... Los Angeles (PRWEB) May 06, 2015 ... WaterAid, the #1 ranked international water, sanitation and hygiene ... work for communities across the world and it brings ... Lindsey Carnett, CEO of Marketing Maven. “The ongoing relationship ... the opportunities available for people to learn about and ...
(Date:5/6/2015)... May 06, 2015 Anitha Nallari, MD ... Hematology Oncology Consultants, Inc. in Columbus, OH. Dr. Nallari ... a special focus in breast cancer, lung cancer, GI and ... as well as benign hematology. , Dr. Anitha ... medicine by the American Board of Internal Medicine. She completed ...
(Date:5/6/2015)... Vancouver, BC (PRWEB) May 06, 2015 ... Center, has recently shared their new blog containing ... originally provided by the Canadian Society for Exercise ... body for physical activity, health and fitness research ... physical activity and exercise are highly beneficial and ...
(Date:5/6/2015)... Jose, California (PRWEB) May 06, 2015 ... of hand sanitizers are increasing, driven by the rising ... preventing the spread of contagious diseases. Hand washing is ... result of consumer apprehension over contracting infections. Periodic outbreak ... as the recent Ebola virus disease (EVD) ...
(Date:5/6/2015)... (PRWEB) May 06, 2015 Healthcare ... user mark after launching in mid-February. The company connects ... who have previous experience in the industry. Likewise, job ... , According to Kyle Johnson, CTO, unique traffic to ... the first month: "Each new job posting brings targeted, ...
Breaking Medicine News(10 mins):Health News:Marketing Maven Expands Partnership with the #1 Ranked International Water, Sanitation and Hygiene Nonprofit 2Health News:Marketing Maven Expands Partnership with the #1 Ranked International Water, Sanitation and Hygiene Nonprofit 3Health News:New Oncologist to Join Hematology Oncology Consultants, Inc. 2Health News:New Oncologist to Join Hematology Oncology Consultants, Inc. 3Health News:Vancouver Chiropractor Shares Canadian Physical Activity and Sedentary Behavior Guidelines by CSEP in New Blog 2Health News:Growing Apprehension Amid Disease Outbreaks Drives Global Sales of Hand Sanitizers, According to a New Report by Global Industry Analysts, Inc. 2Health News:Growing Apprehension Amid Disease Outbreaks Drives Global Sales of Hand Sanitizers, According to a New Report by Global Industry Analysts, Inc. 3Health News:Growing Apprehension Amid Disease Outbreaks Drives Global Sales of Hand Sanitizers, According to a New Report by Global Industry Analysts, Inc. 4Health News:Job Seekers Turn to JobMedic to Find Healthcare Positions - JobMedic.com Reaches 1,000 User Milestone 2
... PRINCETON, N.J., Feb. 19 Medarex, Inc. (Nasdaq: ... its 2008 fourth quarter and year-end results on ... the financial markets close. Following the release, Medarex,s ... webcast at 4:30 p.m. Eastern Time. To access ...
... CVD ) today announced that it has elected ... Dr. Sheares is former chief executive officer and member of ... company that marketed a portfolio of branded cardiovascular medicines. Prior ... Health division of Merck and Co., Inc., where he led ...
... to know the least, survey finds, , , THURSDAY, Feb. 19 (HealthDay ... of a stroke and what to do if they suspect one ... research. , Older people and those who,ve already had a stroke ... the symptoms of a stroke and know to immediately call 911. ...
... PLC, a subsidiary of MGT Capital Investments, Inc. ... development of Computer-Aided Detection (CAD) and image analysis ... of disease, today announces the following restructuring of ... Rowley, currently Chief Financial Officer, becomes Chief Executive ...
... Feb. 19 A groundbreaking new survey sponsored by ... 82% of young adults aged 18-30 plan to get ... 40% of first marriages end in divorce. Why?"There is ... reality of getting or being married," says Mary Myrick, ...
... 2009 A new study released today found blacks ... replacement, an important intervention for reducing pain and improving ... study also found total knee replacements are increasing substantially ... the research underscores the need for healthcare providers and ...
Cached Medicine News:Health News:Medarex to Announce 2008 Fourth Quarter and Year-End Financial Results on Wednesday, February 25, 2009 2Health News:Covance Elects Bradley T. Sheares to Company's Board of Directors 2Health News:Know the Warning Signs of Stroke? Most Don't. 2Health News:Medicsight PLC Restructures Management Team 2Health News:Medicsight PLC Restructures Management Team 3Health News:Young People Want 'Happily Ever After,' but Lack Skills to Make Marriage Work 2Health News:New study finds blacks still lag in obtaining total knee replacements for arthritis 2Health News:New study finds blacks still lag in obtaining total knee replacements for arthritis 3
Provides a combination of concentrated cold / hot and compression for any part of the body...
Provides a combination of concentrated cold / hot and compression for the knee...
Provides extended cold therapy for acute, chronic, or post-surgical applications. Cryotherapy can reduce pain, swelling and speed recovery....
Provides a combination of concentrated cold / hot and compression for the back...
Medicine Products: