Navigation Links
The Leukemia & Lymphoma Society and Memgen Announce New Chronic Lymphocytic Leukemia Clinical Trial
Date:12/3/2008

WHITE PLAINS, N.Y., Dec. 3 /PRNewswire/ -- The Leukemia & Lymphoma Society (LLS) and Memgen, LLC jointly announce the beginning of a new clinical trial of ISF35, a cancer vaccine, at the University of California, San Diego (UCSD).

LLS is collaborating on this trial in the hopes that it will speed the development and approval of a novel approach aimed at treating patients with fludarabine refractory and/or 17p deleted chronic lymphocytic leukemia (CLL).

Doctors at UCSD have already begun treating the first patient with ISF35. They plan to enroll up to twelve patients. These patients will receive a vaccine expressing an immune-boosting molecule, ISF35 (Immune Stimulatory Factor 35), followed by three courses of rituximab plus the chemotherapy drugs fludarabine and cyclophosphamide (FCR).

"This clinical study builds upon three previous trials already completed at M.D. Anderson and here at UCSD," said Januario E. Castro, M.D., assistant clinical professor at the UCSD School of Medicine and the Moores Cancer Center, who leads the work. "Those trials showed remarkable results for ISF35 in patients with high risk and treatment-resistant CLL. Most importantly, ISF35 was well-tolerated with only minimal side effects, reduced CLL cells and lymph nodes in nearly every patient, and when combined with chemotherapy produced complete or partial remissions in patients with 17p deleted CLL."

"There is a clear unmet medical need for new therapies to treat refractory or relapsed CLL, and in particular 17p- patients," said Louis J. DeGennaro, Ph.D., LLS's chief scientific officer. "Our goal is to bring new treatment options to these patients quickly."

For more information about participating in this clinical trial, contact Denise Darrah, at the Moores UCSD Cancer Center, 858-822-5375, or '/>"/>

SOURCE The Leukemia & Lymphoma Society
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Sunesis Announces New Data on Voreloxin for Acute Myeloid Leukemia To Be Presented at ASH
2. St. Jude Identifies Genomic Causes of a Certain Type of Leukemia Relapse
3. Sunesis Pharmaceuticals Presents Clinical Trial Data of Voreloxin in Patients with Acute Myeloid Leukemia and Ovarian Cancer at the Chemotherapy Foundation Symposium
4. Genmab and GlaxoSmithKline Announce Positive Top-Line Results in Ofatumumab Chronic Lymphocytic Leukemia Pivotal Study
5. University of Rochester Researcher Named Millennium Pharmaceuticals Career Development Scholar of The Leukemia & Lymphoma Society
6. The Leukemia & Lymphoma Society and Memgen Collaborate on CLL Clinical Trial
7. Sunesis Pharmaceuticals Presents Data from Clinical Trials of Voreloxin (formerly SNS-595) in Patients with Acute Myeloid Leukemia at the 13th Congress of the European Hematology Association
8. Exelixis Presents Clinical Data Supporting the Safety and Initial Clinical Activity of XL228 in Chronic and Acute Leukemia
9. Micromet and MedImmune Commence Treatment in Phase 2 Trial of BiTE Antibody Blinatumomab (MT103/MEDI-538) in Patients with Acute Lymphoblastic Leukemia
10. Vion Pharmaceuticals Announces Presentation of Interim Data from Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Acute Myelogenous Leukemia at the ASCO(R) Annual Meeting
11. Sunesis Pharmaceuticals to Present Interim Clinical Data From Voreloxin (Formerly SNS-595) Ovarian Cancer Trial at 44th ASCO Annual Meeting and Acute Myeloid Leukemia Trials at 13th EHA Congress
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... , Aug. 28, 2014 Telik, Inc. ... company that merged with MabVax Therapeutics, Inc. on ... significant progress related to the development of its ... was recovered using the Company,s internally developed antibody ... potential for multiple antibody based therapeutic and diagnostic ...
(Date:8/28/2014)... Aug. 28, 2014 Amgen (NASDAQ: ... License Application (BLA) to the U.S. Food and Drug ... of high cholesterol. Evolocumab is an investigational fully human ... (PCSK9), a protein that reduces the liver,s ability to ... the blood. 1 ­ ...
(Date:8/28/2014)... Aug. 28, 2014   RapidForce , an innovative ... a strategic partnership with professional tennis player John ... Isner wears RapidForce during competitions to help with knee ... week at the 2014 US Open Tennis Championships. ... Physio Hybrid Shapes are a revolutionary hybrid of a ...
Breaking Medicine Technology:Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 2Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 3Telik Reports Progress Toward Multiple Early Stage Milestones in the Development of a Novel Antibody-based Therapeutic Agent for Gastrointestinal Cancers 4Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 2Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 3Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 4Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 5Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 6Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 7Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 8Amgen Submits Biologics License Application For Novel Investigational LDL Cholesterol-Lowering Medication Evolocumab To The FDA 9America's top-ranked tennis player John Isner Joins Forces with RAPIDFORCE Physio Hybrid Shapes 2America's top-ranked tennis player John Isner Joins Forces with RAPIDFORCE Physio Hybrid Shapes 3America's top-ranked tennis player John Isner Joins Forces with RAPIDFORCE Physio Hybrid Shapes 4
... NEW ORLEANS, Dec. 5, 2011  At this week,s 46th ... Society of Health-System Pharmacists (ASHP), Cardinal Health launched ... initiatives by making it easier, more timely and cost ... can be scanned at the patient bedside. ...
... 2011  Pharmacy benefit managers Express Scripts and ... unions, and consumers between $51 billion and $87 billion ... a new report released today by economists Jonathan ... Compass Lexecon .  (Logo:  http://photos.prnewswire.com/prnh/20080827/EXPRESSSCRIPTSLOGO ...
Cached Medicine Technology:Cardinal Health Launches Innovative Barcode Administration Solution to Help Hospitals Bridge Gaps in Medication Safety 2Cardinal Health Launches Innovative Barcode Administration Solution to Help Hospitals Bridge Gaps in Medication Safety 3Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 2Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 3Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 4Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 5Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 6Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 7Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 8Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 9Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 10Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 11Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 12Express Scripts and Medco Save Americans Tens of Billions in Healthcare Costs, New Economic Report Shows 13
(Date:8/28/2014)... NJ Top Docs Presents Dr. Christophe Oliveira ... Top Doc, Dr. Christophe Oliveira, has just announced ... for the department of transportation. Dr. Oliveira has ... all drug testing for commercial drivers. , Having ... disorders including disk herniations, spinal stenosis, muscle sprains/strains, ...
(Date:8/28/2014)... (BRONX, NY) Researchers from Albert Einstein College of ... a potential antibody therapy for Sudan ebolavirus (SUDV), one of ... the Zaire ebolavirus (EBOV), is now devastating West Africa. First ... (most recently in 2012) that have killed more than ... ACS Chemical Biology . , Between 30 and 90 ...
(Date:8/28/2014)... In 2012, The Ben & Catherine Ivy Foundation ... brain cancer research projects at the Translational Genomics ... officially received the final regulatory approval from University ... for the trial can begin. , In the ... Trial," TGen and its clinical partners will lead ...
(Date:8/28/2014)... a Chinese herbal medication practitioner in Melbourne for ... a team of intensive care and emergency physicians ... who prescribe complementary medications. , Writing in ... Australasian College for Emergency Medicine, emergency medicine trainees ... the Intensive Care Unit at the Royal Melbourne ...
(Date:8/28/2014)... New York, New York (PRWEB) August 28, 2014 ... continue to mount in courts around the U.S., Bernstein ... & Gynecology is touting devices like Mirena as ideal ... from The Daily Press, the authors of the study ... comes to preventing pregnancy than other methods favored by ...
Breaking Medicine News(10 mins):Health News:NJ Top Docs Presents Dr. Christophe Oliveira of Rehabilitation Instiute of North Jersey 2Health News:NJ Top Docs Presents Dr. Christophe Oliveira of Rehabilitation Instiute of North Jersey 3Health News:Drug shows promise against Sudan strain of Ebola in mice 2Health News:TGen receives approval for patient enrollment in brain cancer clinical trial 2Health News:Deadly remedy: Warning issued about Chinese herbal medicine 2Health News:Mirena IUD Lawsuit News: Bernstein Liebhard LLP Notes New Study Touting IUDs as Ideal Birth Control for Teenage Girls 2Health News:Mirena IUD Lawsuit News: Bernstein Liebhard LLP Notes New Study Touting IUDs as Ideal Birth Control for Teenage Girls 3Health News:Mirena IUD Lawsuit News: Bernstein Liebhard LLP Notes New Study Touting IUDs as Ideal Birth Control for Teenage Girls 4
... a booster vaccination against H5N1 avian influenza given years after ... controlling a potential future pandemic. The study is published ... Infectious Diseases, now available online. , H5N1 continues to ... of mid-June, more than 60 percent of the more than ...
... ADDitude magazine,s top scientific,advisors investigate and explain non-drug ... green time and neurofeedback -,that may relieve ADHD ... how,nutrition, exercise and supplements can help treat ADHD ... magazine, the leading,publication for families and adults living ...
... boost,disability field,s quest to tie in public funding ... 16 One of the most complex,issues in ... and fund,services equitably to people with intellectual and ... Intensity Scale (SIS),assessment tool, developed by the American ...
... days of summer are here, and,for many, the rising ... an,estimated 40 percent of children and 20 percent of ... are spending three billion,dollars a year on antihistamines, often ... say in-vitro blood tests, the,latest generation of allergy tests, ...
... to irregular patterns of light and darkness can cause ... with the 24-hour solar day, negatively affecting human health ... the relationship between circadian disruptions and human maladies. ... Institute,s Lighting Research Center (LRC) provides a new framework ...
... Amsterdam, 16 July 2008 Elsevier, a leading publisher of ... Urology , the official journal of the European Association ... 5.634. , European Urology (also ... papers, fast response and an international profile. To keep up ...
Cached Medicine News:Health News:Booster vaccination may help with possible future avian influenza pandemic 2Health News:Booster vaccination may help with possible future avian influenza pandemic 3Health News:Treating ADHD Symptoms Without Medication: Free Special Report Examines Alternative ADHD Treatments 2Health News:The Supports Intensity Scale Assessment Can be Used to Build Robust Funding Methods for Developmental Disability Services, New Research Reveals 2Health News:New approach sheds light on ways Circadian disruption affects human health 2Health News:New approach sheds light on ways Circadian disruption affects human health 3
Visualize the prostate in both transverse and longitudinal planes....
Super High Density 360 degree radial rectal transducer. High resolution in the near field and lower frequencies for deeper penetration make this transducer the optimal choice when scanning the anal c...
Multi-frequency, HST, linear transducer with a longer (60mm) footprint. Available with puncture adapter and water path. This transducer incorporates ALOKAs exclusive Hemispheric Sound Technology and ...
... high frequency (13Mhz) ... and superficial imaging. ... Hemispheric Sound Technology ... This multi-frequency transducer ...
Medicine Products: