Navigation Links
The Launch of Five Immunomodulatory Therapies for Relapsing Forms of Multiple Sclerosis Will Contribute to 4 Percent Annual Growth of the Total Market from 2013 to 2023
Date:8/7/2014

BURLINGTON, Mass., Aug. 7, 2014 /PRNewswire/ -- Decision Resources Group finds that the forecast launch of Biogen Idec's Plegridy, Roche/Genentech's ocrelizumab, Biogen Idec/AbbVie's daclizumab, Teva/Active Biotech's Nerventra and Receptos' RPC-1063, coupled with the expected U.S. approval of Genzyme/Sanofi/Bayer HealthCare's Lemtrada, will help drive total sales across the multiple sclerosis (MS) market in the United States, France, Germany, Italy, Spain, United Kingdom and Japan to over $20 billion in 2023, reflecting 4 percent annual growth from 2013. Of note, future generics and projected biosimilar competition will cause major-market sales to contract in the latter part of our study period from a 2018 peak of over $22 billion.

Other key findings from the Pharmacor report entitled Multiple Sclerosis:

  • U.S. market dominance of Tecfidera: With greater cross-trial efficacy on relapses than injectable agents, few serious safety risks or monitoring requirements and acceptable tolerability, Tecfidera has experienced robust uptake in the United States. The drug is forecast to become the U.S. market leader by 2015, supported by gradually declining reliance on the platform injectable therapies.
  • Success for follow-on injectables: Despite physicians' and patients' enthusiasm for oral disease-modifying therapies, injectable products remain important current treatment options and comprise a meaningful element of the MS pipeline. We forecast that both Plegridy and Teva's Copaxone 40 mg three-times weekly, two follow-on products offering improved dosing characteristics over time-tested clinical mainstays, will help sustain these companies' respective franchises and earn blockbuster sales during the forecast period.
  • Ocrelizumab's clinical and commercial promise: Interviewed experts express positive opinions about ocrelizumab's potential for strong efficacy in MS as well as its relatively favorable delivery profile. Interviewed thought leaders are quick to note that the drug's safety must be established in ongoing Phase III studies, but they are cautiously optimistic that ocrelizumab may become a preferred agent in later-line MS treatment.

Comments from Decision Resources Group Analyst John Crowley, Ph.D.:

  • "Continued clinical success with anti-inflammatory compounds accentuates the unmet need for bona fide neuroprotective or regenerative therapies for MS. Such an agent could be initiated early in the disease process and/or in combination with immunological agents to benefit the entire spectrum of MS patients. Development in this arena is active—notably with Biogen Idec's Phase II candidate BIIB-033—but advancement overall is constrained by the difficulty of identifying valid drug targets and the optimal design for clinical trials."
  • "Interviewed experts routinely note the pressing unmet need for effective therapies to treat progressive forms of MS. Although experts generally report low expectations for ongoing clinical trials assessing drugs like Tysabri, Gilenya and ocrelizumab, the commercial potential for a successful agent is sizable—we expect a drug's approval for secondary- or primary-progressive MS could result in sales exceeding $1 billion in that population alone."

About Decision Resources Group
Decision Resources Group offers best-in-class, high-value information and insights on critical issues within the healthcare industry. Clients rely on this analysis and data to make informed decisions. Find out more at www.DecisionResourcesGroup.com.

All company, brand, or product names contained in this document may be trademarks or registered trademarks of their respective holders.

For more information, contact:

Decision Resources Group
Christopher Comfort
781-993-2597
ccomfort@dresourcesgroup.com

Logo - http://photos.prnewswire.com/prnh/20130103/MM36768LOGO


'/>"/>

SOURCE Decision Resources Group
Copyright©2014 PR Newswire.
All rights reserved

Related medicine technology :

1. Z Trim Launches Food-Grade Biofiber Gum
2. OSTAR Launches Its A Series Cloud Based Telehealth Vital Signs Patient Monitoring System
3. SOLS Systems Announces Nationwide Launch Of 3D Printed Orthotics
4. Janssen Launches Online Healthy Minds Video Series
5. AARC Launches Virtual Museum
6. InnoPharma Announces Launch of Olanzapine for Injection, 10mg/vial in Canada
7. Drew Crawford Announces Launch of PBM365 Media
8. CPhI South America 2014 Launches with Generics Showing Huge Growth
9. Restore Health Launches Pharmacogenetic Testing, Enhancing Its Suite of Personalized Medicine Goods and Services
10. MDxI Launches Data Resource Setting New Standard for Defining and Targeting US Clinical Laboratory Universe
11. UBM Medica US Launches NeurologyTimes.com
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2017)... and BOSTON , March 27, ... global pharmaceutical company and Paratek Pharmaceuticals, Inc. (Nasdaq: ... and commercialization of innovative therapies based upon tetracycline ... of sarecycline for the treatment of moderate to ... endpoints. Sarecycline is a once-daily, oral, narrow spectrum ...
(Date:3/27/2017)... 27, 2017  PhaseRx, Inc. (NASDAQ: PZRX), a ... liver diseases in children, today reported financial results ... December 31, 2016 and provided an update on ... to make progress during the fourth quarter of ... our non-human primate safety study, and with our lead ...
(Date:3/24/2017)... , Mar 24, 2017 Research ... Therapy Manufacturing Market, 2017-2027" report to their offering. ... The Cell ... the rapidly growing market of cell therapy manufacturing and focuses ... manufacturing facilities. These therapies are anticipated to emerge as viable ...
Breaking Medicine Technology:
(Date:3/27/2017)... ... , ... Harris Communications, Inc., a leading provider of assistive technology for ... Deaf Seniors of America Conference, April 4-7 at the Hotel Westin Galleria in Houston. ... staff from Harris Communications and to try out the newest assistive devices available to ...
(Date:3/25/2017)... ... , ... Getting earned media coverage meaningful for Garden Media Group's clients is ... year, Garden Media aims to provide material helpful to clients’ goals and bottom lines. ... key messages to gain coveted media placements, Garden Media wows clients year-round. , ...
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... ... solutions for contaminated soil, dredged material, and hazardous and non-hazardous materials announced today ... Allentown, Pennsylvania. This acquisition will add four additional processing facilities and a ...
(Date:3/24/2017)... ... March 24, 2017 , ... Mediaplanet today ... conversation on the current obstacles facing infection prevention and offer strategies for the ... by these infections. , The print component of “Fighting Infection” is distributed ...
(Date:3/24/2017)... ... March 24, 2017 , ... Digital Scientists, a software innovation lab specializing in ... a Greenville, South Carolina location. The lab has set up shop at ... been working with South Carolina clients for years from our office here in Atlanta,” ...
Breaking Medicine News(10 mins):