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The Lancet Publishes Two-Year Results of Abbott's Fully Bioabsorbable Drug Eluting Stent
Date:3/12/2009

Data Demonstrate Bioabsorbable Stent Is Absorbed Within Two Years, Leaving Behind Blood Vessels that Appear to Move and Function Similar to Untreated Vessels

ABBOTT PARK, Ill., March 12 /PRNewswire-FirstCall/ -- A comprehensive analysis published today in The Lancet, one of the world's leading medical journals, from the ABSORB clinical trial demonstrated that Abbott's bioabsorbable drug eluting stent, currently in development, successfully treated coronary artery disease and was absorbed into the walls of treated arteries within two years. The two-year data also demonstrated that after the bioabsorbable device was absorbed, the treated blood vessels appeared to move and function similar to unstented arteries. Preliminary findings from the 30-patient ABSORB trial were presented in October 2008 at the Transcatheter Cardiovascular Therapeutics annual meeting in Washington, D.C.

"Abbott's bioabsorbable drug eluting stent leaves behind a vessel that expands and contracts in a manner similar to a vessel that has never been stented, which could be an advantage over permanent metal-based stent implants," said Patrick W. Serruys, M.D., Ph.D., professor of interventional cardiology at the Thoraxcentre, Erasmus University Hospital, Rotterdam, the Netherlands; lead author of The Lancet publication; and co-principal investigator of the first phase of the ABSORB trial. "This bioabsorbable device has the potential to provide optimal vessel scaffolding and drug delivery capability over the crucial first several months after a stenting procedure while avoiding the long-term restrictions of metallic stents."

The ABSORB trial is the world's first clinical trial evaluating a fully bioabsorbable drug eluting coronary stent, and advanced imaging methods were used to assess patient outcomes. As published in The Lancet, the first phase of the ABSORB
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