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The International Serious Adverse Event Consortium and UC San Diego To Collaborate On Research Into The Genetics Of Drug Induced Renal Injury
Date:8/21/2012

CHICAGO, Aug. 21, 2012 /PRNewswire/ -- The International Serious Adverse Events Consortium (iSAEC) announced today it will collaborate with the University of California, San Diego  School of Medicine and UC San Diego Skaggs School of Pharmacy and Pharmaceutical Science to research the genetics of drug induced renal injury (DIRI). The iSAEC is a novel, non-profit international research consortium, funded by the global pharmaceutical industry and the Wellcome Trust, to better understand the role genetics plays in drug safety and response.  UC San Diego is one of the country's top research universities and has an impressive history of pioneering biomedical and scientific research.  The International Drug Induced Renal Injury Consortium (DIRECT) will be supported by the NIH funded O'Brien Center for Acute Kidney Injury Research which is also home to  the International Acute Kidney Injury Registry.  The O'Brien Center is a collaborative research endeavor between the University of Alabama at Birmingham and the University of California, San Diego.

DIRECT will be co-directed by Ravindra L Mehta, MD, Professor of Clinical Medicine in the Division of Nephrology and Associate Chair for Clinical Research, Department of Medicine, Principal Investigator for the UCSD O'Brien Center; and Linda Awdishu, PharmD, Assistant Clinical Professor of Pharmacy.   DIRECT will recruit patients with serious drug induced renal injury reactions, through a collaborative network comprised of 20+ leading clinical research centers from around the world. This collaboration will launch the iSAEC's research into the genetics of drug induced renal injury (DIRI), through a research strategy that focuses on key causal drugs and diverse populations groups that experience this adverse drug reaction.

"Our genetic research points to a strong role of the immune system in these adverse responses." said Arthur L. Holden, Chairman of the iSAEC. "To better u
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SOURCE iSAE Consortium Ltd.
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