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The Hepatitis C virus is the main cause of liver transplant in the world
Date:7/25/2014

ion is in most of the cases asymptomatic and it leads to a chronic infection in 80% of the cases. Of these patients, 20% develop hepatic cirrhosis, which is the previous step to hepatic failure. Of these 20%, from 3% to 5% develop liver cancer.

Not treating the illness may lead to complications that in an important number of patients may lead to the necessity of a liver transplant.  The transplant has additional complications of serious considerations, such as the availability of the organs, the high costs associated to it and the required post-transplant care. This may have severe consequences for the patients as well as for the public health systems.

The paradigm of the Hepatitis C treatment has changed, above all, starting with the arrival of therapeutic alternatives that directly attack the virus, increasing cure rates. We are facing a new era.   Medications that change the regimen of treatment and management of Hepatitis C with higher cure rates in patients infected with HCV (Hepatitis C Virus) genotype 1, which is most predominant genotype in our environment and the most resistant to treatments.

The main goal of the Hepatitis C treatment is to accomplish a sustained viral response (SVR); this means that the virus remains undetectable in the patient´s blood (known as undetectable viral load) six months after finishing the treatment[3]. The patients that achieve an SVR are considered cured.

Telaprevir is part of the Direct-Acting Antivirals (DAAs), which are medications directed to specific enzymes to block important stages of the Hepatitis C virus replication. The DAAs have the potential to help the patients achieve a sustained viral response (SVR).

Telaprevir is a protease inhibitor that is used for only 12 weeks, in all cases, offering this way, a short duration treatment for the patients.

This new therapeutic alternative, presented by the pharmaceutical laboratory Janssen, offers the possibilit
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SOURCE Janssen
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4. Decision Resources to Publish Reports That Include Market Analysis and a Forecast through 2022 for the Hepatitis C Virus and Hospital-Treated Bacterial Infections Drug Markets
5. American Liver Foundation Hails Promise of Cure Signaled by FDAs Approval of New Hepatitis C Treatments
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7. Giant Eagle Expands Specialty Pharmacy with Acquisition, Bringing Treatment Expertise to Customers with Hepatitis C and Organ Transplant Conditions
8. Despite Increasing Cost Sensitivity of EU5 Payers, Sofosbuvir and Simeprevir are Poised to Reshape the Hepatitis C Virus Market by End of 2015
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11. Current Hepatitis C Virus Regimens to Face Stiff Competition with the Launch of Gileads Sofosbuvir and Janssen/Medivirs Simeprevir
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