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The Financial Impact of Obesity in Brazil and Mexico's Healthcare Systems is Driving Partial Coverage of Obesity Drugs in Formularies at the State, Municipal and Hospital Levels
Date:7/22/2013

gents has spurred discussion among the government/payers, providers and industry on how to address the burgeoning costs of obesity on Latin American healthcare systems," said Decision Resources Analyst Andreia Ribeiro, Ph.D. "Payers seek more efficacious therapies and indicate that drugs with different mechanisms of action would be attractive to regulators seeking to expand the obesity treatment armamentarium. Some payers find high value in data from studies directly comparing obesity drugs, but all interviewed payers agree that studies demonstrating cost-effectiveness—a key parameter determined during HTA evaluations in Latin America—are critical to securing formulary inclusion of new drugs."

Several therapies may impact the obesity markets in Brazil and Mexico during the next few years, including Vivus' Qsymia, which appears to offer the best clinical efficacy among marketed or late-stage developmental drugs; Arena/Eisai's Belviq, which offers a more convenient delivery route and dosing schedule than thrice-daily Xenical or the injectable agents currently used off-label; and GLP-1 analogues, which will likely be first choice for (pre)diabetic obese patients. The report findings highlight key positioning attributes for weight-loss agents identified by physicians and payers that may drive Latin America formulary coverage decisions, including cardiovascular safety profile, impact on obesity-related comorbid disease and the downstream cost savings offered to these particular healthcare systems.

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