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The Expected Approval of Velcade Will Be a Significant Driver of Growth in the Graft Versus Host Disease Drug Market
Date:2/7/2013

BURLINGTON, Mass., Feb. 7, 2013 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the expected supplemental approval of Millennium (Takeda)/Johnson & Johnson's Velcade for the treatment of chronic graft versus host disease (GVHD) will be a significant driver of growth in the GVHD market through 2021. In particular, Velcade's uptake in the first-line treatment setting will displace lower-priced standards of care such as corticosteroids and small-molecule immunosuppressants.

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According to Niche Markets and Rare Diseases: Graft Versus Host Disease, expert physicians report that Velcade's market potential could be even greater, based on their interest in employing Velcade in the prophylactic setting. The market opportunity for prophylactic therapies, based on underlying population sizes, is up to three times larger than for primary or later-line treatments.

The report also finds that although the current clinical pipeline is sparse, several drug developers have nevertheless been drawn into GVHD drug development by the potential to secure orphan-drug designation for novel agents.

"GVHD is an excellent illustration of the orphan drug designation working effectively -- without the benefits of the orphan designation, companies might be reluctant to develop drugs for such a small, specific population," said Decision Resources Senior Vice President Cynthia Mundy , Ph.D.

GVHD is a relatively rare condition that occurs in a patient population -- severely ill oncology patients eligible for hematopoietic stem cell transplant -- who already have access to costly sp
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SOURCE Decision Resources
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