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The Epilepsy Drug Market Will Remain Relatively Flat Through 2019 as Generic Erosion, Especially Within the Second-Generation Antiepileptic Drug Class, is Offset by the Launch of New Therapies
Date:10/21/2010

BURLINGTON, Mass., Oct. 21 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, over the next decade, the epilepsy drug market will remain relatively flat, increasing from $2.8 billion in 2009 to $2.9 billion in 2019 in the United States, France, Germany, Italy, Spain, United Kingdom and Japan.

The Pharmacor 2010 findings from the topic entitled Epilepsy forecast a decline in overall sales through 2014 due to generic erosion, specifically within the second-generation antiepileptic drug (AED) class, which will lose approximately $400 million by 2014. Generic erosion within the epilepsy market remains relatively conservative but several popular second-generation AEDs will contend with strong generic competition over the next several years. Nevertheless, the market will recover as a result of uptake of both currently-marketed and emerging higher-priced third-generation AEDs.

"Through 2019, the majority of AEDs will be generically available, creating negative pressure on market growth," said Decision Resources Analyst Nadja Rozovsky, Ph.D. "However, emerging agents, combined with greater uptake of the already-available and mostly branded third-generation AEDs, will temper the impact of generic AEDs, and the market will recover by 2019."

The findings reveal that levetiracetam (UCB's Keppra/Keppra XR, generics) is the current market leader in epilepsy. Driven by its preferred use as both a first-line adjunctive therapy and increasingly as first-line monotherapy, levetiracetam will continue to lead the market in 2019 with approximately $540 million in major-market sales.

The continued uptake of current third-generation AEDs—particularly UCB's Vimpat and Sunovion/Bial/Eisai's Zebinix—and uptake of the emerging AEDs UCB's Rikelta, Valeant/GlaxoSmithKline's Potiga and Eisai's perampanel will offer alternative '/>"/>

SOURCE Decision Resources
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2. Upsher-Smith Laboratories Announces Initiation of Phase III Clinical Trial of USL255 (Extended-Release Topiramate) for Adjunctive Treatment of Partial-Onset Epilepsy
3. Catalyst Pharmaceutical Partners to Present Today at 2010 Epilepsy Pipeline Update Conference
4. Catalyst Pharmaceutical Partners Selected to Present at Epilepsy Conference Highlighting New and Promising Therapies
5. FDA Approves Once-A-Day Lamictal(R)XR(TM) as Add-On Epilepsy Therapy for Primary Generalized Tonic-Clonic Seizures
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9. Video: UCB Launches Vimpat(R) in the U.S. for Add-On Treatment of Epilepsy in Adults
10. VIDEO from Medialink and the Epilepsy Foundation: New Study Suggests Different Versions of the Same Epilepsy Medication Can Be Harmful
11. Retigabine Significantly Reduces the Number of Seizures in Adults With Inadequately Controlled Partial-Onset Epilepsy
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