The technology, said Levy, is highly adaptable. Instead of paclitaxel, it could deliver other therapeutic compounds, DNA for site-specific gene therapy, therapeutic cells, or other treatments. In addition to treating PAD, the technique might carry paclitaxel to narrowed coronary arteries, chemotherapy drugs to a tumor, or other medications to a bile duct or a urinary tract. Eventually, said Levy, the technology could be applied to types of pediatric heart disease, such as primary pulmonary hypertension or heart defects.
As its lab research continues, Vascular Magnetics is moving ahead to attract venture capital. "Our plan is to prove the efficacy of this therapy in humans by late 2015," said Woodward. "The revenue projections for the company suggest sales of over a billion dollars per year within about four years after commercial launch."
"Besides the great potential medical benefit in PAD, commercial success for this technology could enhance our mission of improving children's health—by setting the stage for developing and investing in innovative therapies for children," added Ellen Purpus, Ph.D., director, Office of Technology Transfer at The Children's Hospital of Philadelphia.
About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking third in National Institutes of Health funding. In addition, its unique family-cen
|SOURCE The Children's Hospital of Philadelphia|
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