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The 2012 US Molecular Diagnostics Market
Date:7/4/2012

pendent Gene Amplification

- Sequence Initiation Reaction

- SISPA

- Solid Phase Amplification

C. Detection Technologies

1. Radioactive Methods

a. Overview

b. Major Isotopes P-32 S-35 H-3 I-125

2. Non-Isotopic Methods

a. Enzymatic Labels

b. Chemical Labeling Indirect Chemical Labeling Direct Chemical Labeling

c. Fluorescence

d. Chemiluminescence

e. Electrical Conductivity

D. Instrumentation Review

1. Abbott LCx

2. Beckman Coulter/Biomek FK

3. Becton Dickinson SDA

4. Bio-Rad GeneScope

5. Gen-Probe Tigris

6. Roche Cobas Amplicor

7. Tecan LS Series

E. Biochips: Genosensors, Microarrays, and

Labs-on-the-Chip

- Liquid Transportation and Mixing

- Separation

- Reaction

- Detection

F. Pharmacogenomics

G. Major Applications

1. Microbiology/Infectious Diseases

a. Overview

b. Major Infectious Diseases AIDS Structure and Composition Classification AIDS Origins Animal Lentivirus Systems Virus Receptors HIV Infections in Humans

- Pathogenesis and Pathology CD4T Lymphocytes and Memory Cells Monocytes and Macrophages Lymphoid Organs Neural Cells Viral Coinfections

- Clinical Findings Plasma Viral Load Pediatric AIDS

- Neurologic Disease

- Opportunistic Infections

- Cancer Immunity

- Virus Isolation

- Serology

- Viral Nucleic Acid/Antigen Detection Epidemiology

- Worldwide Spread of AIDS

- United States

- Routes of Transmission DNA Probes

- Overview

- Quantitative PCR

- In Situ PCR

- Needed Improvements Viral Load/Drug Resistance Testing Genotype and Phenotype Testing Blood Banking Considerations Adenovirus Background Diagnostic Tests Vaccines and Drugs Adeno-Associated Viruses (AAV) Anthrax/Bacillus Anthracis Background Diagnostic Tests Vaccines and Drugs Babe
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