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Texas Children's Hospital is first in North America to own Leica Microsystems Gated Stimulation Emission Depletion microscope
Date:8/20/2012

he current treatment options and find novel therapies for a variety of illnesses by better understanding the human immune system."

Orange's research focuses on the biology of natural killer cells and the innate immune system, with a clinical focus on primary immunodeficiency disease. He has received funding from the National Institute of Allergy and Infectious Diseases, as well as the United States Immunodeficiency Network to support his laboratory work.

Over the past decade, Orange has invigorated the field of human natural killer cell deficiencies in various genetic disorders. He recently collaborated with European researchers who achieved marked clinical improvements in using gene therapy to treat young children with Wiskott-Aldrich syndrome, a rare but often severe immunodeficiency disorder. He is currently conducting clinical trials testing the use of immunotherapy to boost immune function in children with Wiskott-Aldrich syndrome. His use of advanced imaging technologies has enabled otherwise impossible insights into these rare diseases and overall into human immune defenses.

About Texas Children's Hospital

Texas Children's Hospital, a not-for-profit organization, is committed to creating a community of healthy children through excellence in patient care, education and research. Consistently ranked among the top children's hospitals in the nation, Texas Children's has recognized Centers of Excellence in multiple pediatric subspecialties including the Cancer and Heart Centers, and operates the largest primary pediatric care network in the country. Texas Children's has completed a $1.5 billion expansion, which includes the Jan and Dan Duncan Neurological Research Institute; Texas Children's Pavilion for Women, a comprehensive obstetrics/gynecology facility focusing on high-risk births; and Texas Children's Hospital West Campus, a community hospital in suburban West Houston.  For more information on Texas Children's, go to
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SOURCE Texas Children's Hospital
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