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Tetra Discovery Partners Receives Major NIH Award To Develop New Alzheimer's Drug
Date:6/19/2012

GRAND RAPIDS, Mich., June 19, 2012 /PRNewswire/ -- Tetra Discovery Partners LLC, a leader in the design of new treatments for major neurological conditions based on PDE4 modulation in the brain, today announced it has been awarded a five-year cooperative agreement by the National Institutes of Health (NIH).  The award will support Tetra's efforts to develop a new drug to treat mild cognitive impairment, which is typically associated with aging and often precedes and accompanies Alzheimer's disease.

Tetra's award includes up to $1.5 million in direct funding and access to millions of additional dollars worth of contracted research services; the Company estimates that the total value of the NIH award to be worth at least $10 million over the project's anticipated five-year period.  The award was made through the Blueprint Neurotherapeutics Network (BPN), a recently launched NIH initiative involving the National Institute of Neurological Disorders and Stroke and the National Institute of Aging.  Under the terms of its cooperative agreement with NIH, Tetra will retain the intellectual property related to its research and be responsible for the commercialization of the new drug.

"We are delighted that Tetra Discovery Partners has been accepted into NIH's highly selective Blueprint Neurotherapeutics Network," said Mark Gurney, Ph.D., Tetra's founder and president.  "We expect that the funding and access to industry resources provided by the BPN will help support the significant acceleration of Tetra's work, which holds real promise for the millions of individuals and families contending with age-related cognitive decline and the ravages of Alzheimer's."

Tetra's research focuses on designing drugs that inhibit phosphodiesterase 4 (PDE4), a key enzyme in the brain that controls the biochemical process of memory.  The compounds designed by Tetra act like a type of molecular glue, closing a "lid" over the PDE4 catalytic si
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SOURCE Tetra Discovery Partners LLC
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