Navigation Links
Tengion Launches Second Phase 2 Clinical Trial of Regenerated Human Organ
Date:9/17/2007

Trial Aims to Study Safety and Efficacy of Tengion's Neo-Bladder Construct

in Spinal Cord Injury Patients

EAST NORRITON, Pa., Sept. 17 /PRNewswire/ -- Tengion, Inc., a leader in regenerative medicine, announced today it has initiated a Phase 2 multi-center clinical trial of its neo-bladder construct, derived from a patient's own cells. The U.S.-based study is being conducted in 10 adult patients with neurogenic bladder due to spinal cord injuries. Neurogenic bladder is a condition that can occur due to spinal cord injury and may lead to kidney failure and incontinence, even when patients receive optimal medical treatment.

This Phase 2 trial initiation follows the successful completion of enrollment in the company's first (Phase 2) clinical trial of the autologous neo-bladder construct in pediatric patients with neurogenic bladder due to spina bifida. The commencement of Tengion's spina bifida Phase 2 clinical trial was announced in the first quarter of 2007.

"Tengion's novel regenerative medicine platform aims to address the significant limitations of current treatment options for patients with organ and tissue failure or loss," said Steven Nichtberger, M.D., President and CEO of Tengion. "Our neo-bladder constructs, which harness the body's natural ability to regenerate organs and tissues using a patient's own cells, hold the promise to meet critically important unmet medical needs. We look forward to announcing results from both of these Phase 2 clinical studies."

Similar to the Phase 2 study in pediatric patients, the new Phase 2 study in adult patients with spinal cord injuries is evaluating the safety and effectiveness of the neo-bladder construct at one year after implantation. The neo-bladder construct design is based on nearly two decades of research from Children's Hospital Boston (a teaching affiliate of Harvard Medical School), MIT, The Wake Forest Institute for Regenerative Medicine and Tengion. Previ
'/>"/>

SOURCE Tengion, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
2. Second Phase III Study Evaluating Gileads Viread for the Treatment of Chronic Hepatitis B Virus Meets Primary Endpoint
3. Second Phase III Study Evaluating Gileads Viread for the Treatment of Chronic Hepatitis B Virus Meets Primary Endpoint
4. Second Successful Quigley QR-443 Study Suggests Method of Action Relevant to Broad Range of Chronic Inflammatory Diseases - Human Study to Follow -
5. NeurogesX Announces Presentation of Positive Phase 3 Clinical Data at the Second International Congress on Neuropathic Pain Meeting (NeuPSIG)
6. Repros Androxal Shows Highly Statistically Significant Positive Effects in Men with Secondary Hypogonadism
7. Pharmions Amrubicin Shows Encouraging Results Compared to Standard of Care in Second Line Treatment of Small Cell Lung Cancer
8. Positive Results for Second-Generation Taxus Liberte Coronary Stent System Highlighted in Journal of American College of Cardiology
9. Kosan Presents Promising Phase 1 Data on Second-Generation Hsp90 Inhibitor, Alvespimycin, Showing Antitumor Activity in Refractory Breast and Ovarian Cancers at ASCO
10. Gilead Announces Achievement of Primary Efficacy Endpoint in Second Phase III Study of Aztreonam Lysine for Inhalation in Patients With Cystic Fibrosis
11. Amlodipine and Olmesartan Study Results Released;Late Breaker Presented at American Society of Hypertension Twenty-Second Annual Scientific Meeting (ASH 2007)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... 2014 Surgeons at The Children,s Hospital of ... report the first successful use of a SynCardia temporary ... with failing Fontan circulation to bridge him to a ... old, the patient received a Fontan circulation procedure to ... "The Fontan operation is the final planned palliative operation ...
(Date:9/16/2014)... Va. , Sept. 16, 2014 ... Medical Directors Institute has simultaneously released the NAMCP ... NAMCP Medical Diagnostics Dossier Template © , which ... template formats for either medical devices or diagnostics ... aspects of each of these technology types (instead ...
(Date:9/16/2014)... , Sept. 16, 2014 The Lupus ... LLY ) today released results from UNVEIL: ... sheds light on the lupus journey and the challenges ... for lupus caregivers. The UNVEIL study, which involved over ... devastating impact lupus has on all aspects of life ...
Breaking Medicine Technology:13-Year-Old Boy with Failed Fontan Circulation Bridged to Transplant Using the SynCardia Total Artificial Heart, Published in Annals of Thoracic Surgery 213-Year-Old Boy with Failed Fontan Circulation Bridged to Transplant Using the SynCardia Total Artificial Heart, Published in Annals of Thoracic Surgery 3NAMCP Medical Directors Institute releases NAMCP Medical Technologies and Diagnostics Dossier Templates to provide model approach for medical devices or diagnostics 2"UNVEIL" Survey Reveals a Life Interrupted by Lupus 2"UNVEIL" Survey Reveals a Life Interrupted by Lupus 3"UNVEIL" Survey Reveals a Life Interrupted by Lupus 4"UNVEIL" Survey Reveals a Life Interrupted by Lupus 5
... The Netherlands, July 16 Neurofeedback - also,called EEG ... activity in order to,normalize Brain function and treat psychiatric ... 10 years, however the question,whether this treatment should be ... a study will be published in the scientific,journal ,EEG ...
... , , BOSTON and ... IIb multinational study(1) with edoxaban(2) - an investigational oral Factor ... atrial fibrillation (AF) receiving edoxaban once daily (QD) experienced fewer ... The analysis finds that bleeding associated with edoxaban is most ...
Cached Medicine Technology:New Research Shows: Neurofeedback is an 'Evidence-Based' Treatment for ADHD 2Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing 2Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing 3Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing 4Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing 5
(Date:9/16/2014)... Today, Top10BestSEOHosting.com compares many ... USA and announces that HostMonster, Arvixe and ... Windows web hosting companies in the market. ... high quality WordPress hosting (including VPS and ... HostMonster provides outstanding customer support and a ...
(Date:9/16/2014)... (PRWEB) September 16, 2014 Not all ... they take care to make sure all their patients ... For some, this may include the newly-introduced online therapy. ... program which gives patients the opportunity to seek treatment ... can provide medical and clinical care at a distance. ...
(Date:9/16/2014)... Aspen Advisors, a U.S.-based healthcare IT consulting firm, ... high morale and collaborative culture in the ... Work For 2014.” Consulting magazine publishes the popular ... participating across all major industries, representing more than 350 ... firms were ranked in six categories - firm culture, ...
(Date:9/16/2014)... may one day be able to predict when and ... sexual functioning, thanks in part to new findings that ... American Society for Radiation Oncology,s 56th Annual Meeting on ... more than 17,000 surveys completed by men diagnosed with ... and sexual symptoms changed following each type of treatment, ...
(Date:9/16/2014)... September 16, 2014 Who:, The Pulmonary ... Medical Campus and Children’s Hospital Colorado are ... the country’s leading pulmonary hypertension association that works to find ... disease of the lungs that affects the functioning of the ... mean survivability is only 2.8 years. , What:, Colorado ...
Breaking Medicine News(10 mins):Health News:Best Windows Web Hosting Suppliers Recommended By SEO Hosting Review Site Top10BestSEOHosting.com 2Health News:Millennium Treatment Group Now Offers Online Therapy 2Health News:Aspen Advisors Earns Recognition in Consulting Magazine’s "Best Small Firms to Work For" 2Health News:Aspen Advisors Earns Recognition in Consulting Magazine’s "Best Small Firms to Work For" 3Health News:Study identifies when and how much various prostate cancer treatments will impact urinary and sexual functioning 2Health News:Study identifies when and how much various prostate cancer treatments will impact urinary and sexual functioning 3Health News:Help Fight Pulmonary Hypertension at the Colorado PH in the Park 2014 2
... Insurance Convention Expected to Draw ... Protestors to San Francisco,Delgadillo to Discuss Legal Efforts to Crack Down ... and Unfair Business Acts and Practices" of Insurers, SAN ... of,protest against health insurance corporations, Los Angeles City Attorney,Rocky Delgadillo will ...
... the team that made the discovery, Professor Christopher Rowe ... and treatment presents medical practitioners with the best opportunity ... is at an experimental stage, this work places Australia ... Rowe says. , A 2004 Access Economics report calculated ...
... marks, get set go to lane 1? , ... connection between loud sounds and reaction time are reporting findings ... the upcoming Olympics. , Led by Dave Collins, professor ... hypothesized that the loud starter,s pistol at the Olympic Games ...
... Introduces ,The Insight, First ,Webisode, Featuring Guest, Hosts, Live Call-ins, ... ... Dealing With Change, BOCA RATON, Fla., ... Florida,s first weekly webisode -- a,transformational show called "The Insight" ...
... SAN CARLOS, Calif., June 18 Nuvelo, Inc.,(Nasdaq: ... the company,s chairman,and chief executive officer, will present at ... 2008, at 1:30 p.m. ET in New,York City., ... available online via,the Investor Relations portion of Nuvelo,s website ...
... ARAY ), a global leader in the field ... officer, Euan S.,Thomson, Ph.D., is scheduled to present at ... 10:15 a.m. EDT (7:15 a.m. PDT)., A live ... the,investor relations page of the Company,s Web site at, ...
Cached Medicine News:Health News:L.A. City Attorney Rocky Delgadillo, Patient Activists to Unveil New Television Ad Targeting Health Insurers 2Health News:L.A. City Attorney Rocky Delgadillo, Patient Activists to Unveil New Television Ad Targeting Health Insurers 3Health News:Advance towards early Alzheimer's diagnosis 2Health News:Sprinters closest to starter pistol have advantage over those farther away, says study 2Health News:A South Florida Premiere 2Health News:Accuray Incorporated's CEO to Speak at Jefferies Second Annual Healthcare Conference 2
... compatible with hood installations. ... system for 384-well plates, ... prepares large quantities of ... Wellpro also performs plate ...
... 96 is a compact and self-contained multichannel ... tip manifold can be used in a ... in the optional active wash system. ... and adds safety. Optional ...
... for low volumes. Dispenses volumes down to ... Fast throughput of less than 30 seconds ... features an intuitive user interface that provides ... dispense liquids and suspensions, beads, or cells, ...
... Personal Pipettor is a cost-effective ... pipetting needs, from reagent additions ... more. Systems are available in ... using either fixed or disposable ...
Medicine Products: