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Tengion Announces Significant Advances in Neo-Urinary Conduit™ and Neo-Kidney Augment™ Programs
Date:3/26/2012

WINSTON-SALEM, N.C., March 26, 2012 /PRNewswire/ -- Tengion, Inc. (NASDAQ: TNGN), a leader in regenerative medicine, today announced that it has made significant advances in its two lead programs. A fourth patient was implanted in the last several weeks in the ongoing initial clinical trial of the Company's lead product candidate, the Neo-Urinary Conduit. The Company also submitted a pre-Investigational New Drug (IND) filing to the U.S. Food and Drug Administration (FDA) for its lead preclinical program, the Neo-Kidney Augment. Tengion also announced its fourth quarter and full year 2011 financial results in a separate release issued today and will hold a conference call to discuss these updates today, March 26, 2012, at 5:00 p.m. EDT.

"The implanting of the Neo-Urinary Conduit into the fourth patient and the pre-IND filing for our Neo-Kidney Augment are significant achievements for Tengion and we are confident in our ability to execute on our ambitious objectives for these two programs going forward," stated John L. Miclot, President and Chief Executive Officer of Tengion. "We have gained substantial knowledge and insight from the first three patients in the ongoing trial for the Neo-Urinary Conduit and we believe that the surgical modifications implemented for the fourth patient will improve outcomes for current and future patients in the trial. In addition, now that we have submitted a pre-IND filing to the FDA for the Neo-Kidney Augment, we are preparing a proposed clinical trial design and timeline to continue our progress toward establishing clinical proof of concept."

Neo-Urinary Conduit Clinical Program Update
Tengion has now enrolled a fourth patient in the ongoing initial clinical trial of its lead product candidate, the Neo-Urinary Conduit, which is being evaluated in bladder cancer patients requiring a urinary diversion following bladder rem
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Related medicine technology :

1. Tengion Appoints John L. Miclot President and Chief Executive Officer
2. Tengion to Present at Piper Jaffray 23rd Annual Health Care Conference
3. Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results
4. Tengion Appoints Scott Flora to Board of Directors
5. Tengion Appoints Diane Jorkasky, M.D., to its Board of Directors
6. Tengion Provides Update on Neo-Urinary Conduit Clinical Trial
7. Tengion Announces FDA Orphan-Drug Designation for Neo-Urinary Conduit
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10. Tengion Provides Business Update and Reports Third Quarter 2010 Financial Results
11. Tengion Reviews Pipeline Progress at First Analyst and Investor Meeting; Strategic & Clinical Updates Provided for Regenerative Medicine Programs
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