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Tengion Advances Clinical Trial for Neo-Urinary Conduit™ in Bladder Cancer Patients
Date:11/16/2010

EAST NORRITON, Pa., Nov. 16, 2010 /PRNewswire-FirstCall/ -- Tengion, Inc. (Nasdaq: TNGN), a leader in regenerative medicine, announced today that the scheduled one-month, post-operative clinical assessment of the first implanted bladder cancer patient in its ongoing clinical trial has been completed as expected and has permitted the second patient to be enrolled without delay.  The protocol for this initial clinical trial calls for each of the first few patient implantations to occur at least eight weeks after the previous patient surgery.  The surgical procedure may be modified in subsequent patients based on the experience gained by the prior patient(s) enrolled.  No modifications to the protocol have been made based on the experience with the first patient.

"We are very encouraged by the response we have seen so far in our first patient and we look forward to continuing to advance this trial and to enrolling additional patients," commented Sunita Sheth, M.D., Vice President and Chief Medical Officer at Tengion.

This trial is evaluating Tengion's Neo-Urinary Conduit in bladder cancer patients requiring a urinary diversion following bladder removal (cystectomy).  The ongoing study is designed to provide data on the safety profile for the Neo-Urinary Conduit as well as to optimize the surgical technique and the ideal post-surgical patient care before proceeding into larger trials.  The first two patients are being treated at the University of Chicago Medical Center by the principal investigator at the site for this study, Gary D. Steinberg, M.D., Professor of Surgery and Director, Urologic Oncology. The trial is also being conducted at a second clinical site at The Johns Hopkins Hospital in Baltimore, Maryland.

Tengion expects to implant five patients by the middle of 2011 with scheduled three-month clinical assessments on all patients e
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SOURCE Tengion, Inc.
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Related medicine technology :

1. Tengion Launches Second Phase 2 Clinical Trial of Regenerated Human Organ
2. Tengion Launches Third Phase 2 Clinical Trial of Regenerated Human Bladder
3. Preclinical Data Demonstrate Ability to Regenerate an Entire Bladder With Tengion Neo-Bladder Replacement(TM)
4. Tengion Scientists Publish Key Preclinical Findings Demonstrating the Benefits of Organ Regeneration Vs. Repair
5. Tengion Appoints Sunita B. Sheth, M.D., Chief Medical Officer
6. Tengion Presents New Data Demonstrating Functional Regeneration in a Diabetic Chronic Kidney Failure Model at the International Society for Cellular Therapy
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