Navigation Links
Telik Announces the Publication of Two Reports in the Journal Of Hematology & Oncology Describing the Results of a Clinical Study of Telintra® in Combination With Revlimid® and a Genomic Study Designed to Identify Genes That Predict Response to Teli
Date:5/15/2012

d a variable risk of transformation to acute myeloid leukemia.  It is estimated that MDS affects approximately 300,000 people worldwide.  According to the American Cancer Society, 10,000–20,000 new cases of MDS are diagnosed each year in the United States, with survival rates ranging from six months to six years.  MDS patients often require multiple blood transfusions to manage their disease.

Telintra has a novel mechanism of action that inhibits an enzyme called glutathione S-transferase P1-1, which leads to activation of Jun kinase, a key regulator of cellular growth and differentiation of blood precursor cells; this mechanism induces cancer cell death, or apoptosis, in human leukemia cell lines. Telintra is also being evaluated in a Phase 2 clinical trial in Revlimid refractory and resistant deletion 5q MDS patients and a Phase 2b clinical trial in non-deletion 5q MDS patients.  Additional information about Telintra is available at www.telik.com.

About Telik, Inc.

Telik, Inc. of Palo Alto, CA, is a clinical-stage drug development company focused on discovering and developing small-molecule drugs to treat cancer.  The company's most advanced drug candidate is Telintra, a modified glutathione analog intended for the treatment of hematologic disorders including myelodysplastic syndrome, followed by Telcyta®, a cancer-activated prodrug for the treatment of a variety of cancers.  Telik's product candidates were discovered using its proprietary drug discovery technology, TRAP®, which enables the rapid and efficient discovery of small-molecule drug candidates.

This press release contains "forward-looking" statements regarding the future development of Telintra, the safety and effectiveness of Telintra in treating MDS, whether Telintra treatment results in hematologic improvement in patients with MDS, whether Telintra reduces the need for, or offer
'/>"/>

SOURCE Telik, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Telik Regains Compliance With Minimum Bid Price Requirement
2. Telik Announces Fourth Quarter and 2011 Year End Financial Results and 2012 Financial Guidance
3. Telik Announces Presentation and Webcast at 14th Annual BIO CEO & Investor Conference
4. Telik Announces Telintra Clinical Presentations at the Annual Meeting of the American Society of Hematology
5. Telik Announces Third Quarter 2011 Financial Results
6. Telik Announces Publication of a Report of Complete Response of G-CSF Resistent Severe Idiopathic Chronic Neutropenia Following Treatment with Telintra®
7. Telik Announces Ezatiostat (Telintra®) Preclinical Presentation at the 2011 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
8. Telik Announces Initiation of a Phase 2b Clinical Trial of Telintra® (Ezatiostat HCL) in Patients With Low to Intermediate-1 Risk Non-Deletion (5q) Myelodysplastic Syndrome
9. Telik Announces Publication in the Journal Cancer of a Phase 2 Randomized Multicenter Study of Two Extended Dosing Schedules of Oral Ezatiostat in Low to Intermediate-1 Risk Myelodysplastic Syndrome
10. Telik Announces First Quarter 2011 Financial Results
11. Telik Announces Presentation of New Data on the Characterization of Novel Ezatiostat (TELINTRA®, TLK199) Analogs at American Association for Cancer Research Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... , Aug. 29, 2014  Abaxis, Inc. (NasdaqGS: ... point-of-care blood instrumentation and consumables to the medical, research ... , Chairman and Chief Executive Officer, will present at ... Conference 2014 on Tuesday, September 9, 2014 at 12:30 ... Omni Berkshire Place Hotel in New York ...
(Date:8/29/2014)... and MENLO PARK, Calif. , Aug. ... (OTCQB: DMPI) ("DelMar" "the Company") today announced the ... The Company recently changed its fiscal year end to ... list its common stock on a national securities exchange ... statements as filed with the United States Securities Exchange ...
(Date:8/29/2014)... Research and Markets  has announced the addition of ... 2014-2018" report to their offering. ... connect, support, or surround bones. There are several types ... fascia, and other fibrous tissues. Repetitive use, accidents, injuries, ... in wear and tear in these tissues. Orthopedic soft ...
Breaking Medicine Technology:Abaxis, Inc. to Present at CL King's 12th Annual Best Ideas Conference 2014 2DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 2DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 4DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 5Global Orthopedic Soft Tissue Repair Devices Market 2014-2018: Key Vendors are ArthroCare, Biomet, DePuy Synthes and Smith & Nephew 2Global Orthopedic Soft Tissue Repair Devices Market 2014-2018: Key Vendors are ArthroCare, Biomet, DePuy Synthes and Smith & Nephew 3
... 23, 2012  Northwest Biotherapeutics (OTC.BB: NWBO) (NW Bio) today ... open and recruiting across the United States in its ... for Glioblastoma multiforme (GBM), the most lethal form of ... schedule, as the Company had projected to reach it ...
... 2012  One thousand ... have now been identified as a result of the   ... now drastically reduce the risk of painful fractures because inexpensive ... of mammography clinics throughout Europe are using this service to ...
Cached Medicine Technology:NW Bio Reaches 30 Clinical Trial Sites Ahead of End-of-Q1 Projection 2NW Bio Reaches 30 Clinical Trial Sites Ahead of End-of-Q1 Projection 31,000th Woman Identified Using Sectra's Analysis Method - European Mammography Clinics Mark Milestone in the Struggle Against Osteoporosis 21,000th Woman Identified Using Sectra's Analysis Method - European Mammography Clinics Mark Milestone in the Struggle Against Osteoporosis 3
(Date:8/30/2014)... 30, 2014 In today’s world, a ... difficult to get. Snoring and sleep apnea (a medical ... stops) robs people and their bed partners of the ... to 45% of the population snores and 20 million ... Of these, only 10% have been diagnosed and treated; ...
(Date:8/30/2014)... 2014 Top10BestSEOHosting.com is a well-known ... announced that HostGator.com http://secure.hostgator.com/~affiliat/cgi-bin/affiliates/clickthru.cgi?id=seohosts is the ... Also, they has announced that Bluehost and Arvixe ... Hostgator, one of the Top 10 Web Hosting ... Windows hosting, and it offers rich features and ...
(Date:8/30/2014)... August 30, 2014 Removecomplaints.net, a well-known ... industry, has announced to offer guarantee of results with ... offer this guarantee because of its tremendous track record. ... clients from all over the world and received recommendation ... job. , On being asked about the announcement, ...
(Date:8/30/2014)... August 30, 2014 LiveStreamingFitness.com, a company dedicated ... other healthy lifestyle resources, is proud to announce it has ... for at home fitness solutions by ABC’s Good Morning America. ... story on ABC’s Good Morning America, “Live Streaming Fitness is ... streamline your day by streamlining your workout…to boot camp at ...
(Date:8/30/2014)... Jake W., 18, is completing his high ... Back2Basics Outdoor Adventures transition program known as Beyond the ... I can actually start on a real career path,” said ... done.” , He has six months of sobriety under his ... choose to continue on to the Beyond the Basics transition ...
Breaking Medicine News(10 mins):Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:Top10BestSEOHosting.com: HostGator.com Is The Best Windows Hosting Supplier 2Health News:Removecomplaints.net Announces Guaranteed Complaints Removal Services 2Health News:LiveStreamingFitness.com is New Trend In Fitness 2
... whether procedures were legal, illegal, survey also found , , FRIDAY, ... fell worldwide from almost 46 million in 1995 to less ... one in every five pregnancies ends in abortion, the global ... declined. , The report, by researchers at the Guttmacher Institute ...
... enteral nutrition is a breakthrough in the management ... current available clinical studies early nasogastric enteral nutrition ... , Three randomized controlled clinical trials were eligible, ... were randomly assigned to the early nasogastric enteral ...
... -- along with thousands of,herb-loving individuals, organizations and ... Day 2007 tomorrow, Oct. 13. The company will,continue ... by giving,customers free 28-ct Mega Men(R) or Women,s ... on herbs. National Herb Day recognizes the ...
... 12, 2007 For the first time, scientists have ... to a specific, chemical signature that may be ... laboratory tests. The signature reads chocolate lover in some ... the researchers say. , The study by Swiss ...
... GUANGZHOU, China, Oct. 12 /Xinhua-PRNewswire-FirstCall/ -- ... CHME), a leading,distributor of prescription and ... medicines (finished medicines made of Chinese ... medical,supplies and medical formulations today announced ...
... (NYSE: SRZ ) today announced that it had ... Sunrise,s 2007 annual,meeting of stockholders to be held at ... McLean Tysons Corner, 7920 Jones Branch Drive, McLean,Virginia. As ... the Delaware Chancery Court on September 5, 2007, as ...
Cached Medicine News:Health News:Abortion Numbers Fall Worldwide 2Health News:Abortion Numbers Fall Worldwide 3Health News:Short-term hemofiltration is cost-effective for severe acute pancreatitis 2Health News:GNC Honors Herb Day Tomorrow (and All Month Long) 2Health News:Study finds that people are programmed to love chocolate 2Health News:China Medicine's ADTZ Project Has Been Selected as One of Six Patent Commercialization Projects in Guangdong Province 2Health News:Sunrise Settles Litigation Regarding Its 2007 Annual Meeting 2
... The Quality Module QS I evaluates ... of centrifuged serum samples. The System ... and recognizes if a sample contains ... with the Aliquoting System RSD 800A ...
... is an individually configurable System for decapping, ... via cap recognition is optional) which is ... a clearly organized workflow. The input and ... high capacity. The System can simply be ...
... combination of the Aliquoting System RSD 800A ... ACM-8). This turns out in an efficient ... laboratory. The System automates all important front-end ... via cap identification, sample quality control, decapping, ...
... Aliquoting System RSD 800A is an individually ... archiving (additional tube type identification via cap ... process various sample tubes in a clearly ... areas are customized and offer high capacity. ...
Medicine Products: