Navigation Links
Telik Announces Publication of Positive Phase 1-2a Results of a Multicenter Study of TELCYTA(R) in Combination With Carboplatin and Paclitaxel in Patients With Advanced Non-Small Cell Lung Cancer
Date:10/1/2009

PALO ALTO, Calif., Oct. 1 /PRNewswire-FirstCall/ -- Telik, Inc. (Nasdaq: TELK) today announced the publication of the positive results from a Phase 1-2a multicenter, dose-ranging study of TELCYTA in combination with carboplatin and paclitaxel as first-line therapy for patients with nonsmall cell lung cancer (NSCLC) in a leading peer reviewed publication, the Journal of Thoracic Oncology, October 2009; Vol. 4, No. 10. Data on this study were presented at the 98th annual meeting of the American Association for Cancer Research (AACR) on April 17, 2007.

One hundred twenty-nine patients were treated with TELCYTA in combination with carboplatin and paclitaxel, of whom 100 were continuing to respond at the end of combination therapy and eligible to receive single agent TELCYTA maintenance therapy. Those patients who received the TELCYTA combination therapy followed by TELCYTA maintenance therapy vs. no maintenance therapy had a median progression-free survival (PFS) of 6.8 months vs. 3.9 months, respectively (p< 0.0001). The difference in PFS correlated with a median survival of 16.8 months in the maintenance group vs. 8.8 months for those without maintenance therapy (p<0.0001). TELCYTA in combination with carboplatin and paclitaxel chemotherapy followed by TELCYTA maintenance therapy was well tolerated. TELCYTA may be suited to application as maintenance therapy, an area of current intense interest for the treatment of lung cancer patients. In addition, the regimen appeared active across all types of NSCLC and ongoing investigations are attempting to identify the characteristics of the NSCLC population most likely to benefit from this approach.

About Telik

Telik, Inc. of Palo Alto, CA, is a clinical stage drug development company focused on discovering and developing small molecule drugs to trea
'/>"/>

SOURCE Telik, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Telik Announces Presentation of Preclinical Data on Dual Inhibitors of Aurora Kinases and VEGFR2
2. Telik Announces Preclinical Data Demonstrating Anti-Cancer Activity of Dual Inhibitors of Aurora Kinase and VEGFR2
3. Telik Announces Telintra Presentation at American Society of Hematology Annual Meeting
4. Telik Announces Initiation of Two Phase 2 Randomized TELINTRA Studies
5. Teliks Proteasome Inhibitor Program Meets a Preclinical Development Milestone
6. Telik Announces Presentation at ASCO Annual Meeting
7. Telik Announces Publication of Positive Phase 1 Results of a Multicenter Study of Ezatiostat Hydrochloride (TELINTRA(R), TLK199) Tablets In Patients With Myelodysplastic Syndrome
8. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
9. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
10. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
11. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... -- Allowing more basic emergency medical service (EMS) staff ... involve opioids, according to a Centers for Disease Control ... Emergency Medical Service Providers and the Burden of Drug ... Journal of Public Health . In 2013, ... States involved prescription opioids, and more than ...
(Date:4/24/2015)... 24, 2015  New technologies and online platforms ... educate themselves about products and companies. Likewise, these ... available to market researchers seeking insights into consumer ... it,s imperative that organizations adjust their consumer marketing ... opportunities, niches and growth fronts. ...
(Date:4/24/2015)... 2015 Boston Scientific Corporation (NYSE: BSX ) ... Annual Healthcare Conference on May 6 in ... vice president and chief financial officer, and Susie Lisa ... question and answer session regarding the company with the host ... webcast of the presentation and question and answer session will ...
Breaking Medicine Technology:Expanding Naloxone use could reduce drug overdose deaths and save lives 2Expanding Naloxone use could reduce drug overdose deaths and save lives 3Pharmaceutical Industry Using New Technologies to Adjust Their Marketing and Research Approaches for Consumers 2Boston Scientific To Participate In The Deutsche Bank 40th Annual Healthcare Conference 2
... key role in treatment discovery, MELBOURNE, Australia, ... Cytopia Limited (ASX: CYT) announced today that its ... in cells,isolated from patients with myeloproliferative disorders (MPDs)., ... there is over-production of,particular cells within the blood ...
... Tigris Pharmaceuticals,Inc., a privately held drug development company, ... study of aminoflavone,pro-drug (AFP-464) for the treatment of ... and enrollment is ongoing., The primary objectives ... limiting,toxicity (DLT) and maximum tolerated dose (MTD) of ...
Cached Medicine Technology:JAK2 Inhibitor Shows Potent Activity in Cells From MPD Patients 2Tigris Pharmaceuticals Initiates Phase I Study of AFP-464 in Patients with Solid Tumors 2Tigris Pharmaceuticals Initiates Phase I Study of AFP-464 in Patients with Solid Tumors 3
(Date:4/24/2015)... April 24, 2015 Ryadon is a ... range of capabilities and services to complement any custom ... Quantity Discount Program will be offered on all heavy ... Order 4-19: Receive 10% discount - Order 20+: Receive ... the Drawer Slides Products, Furniture ...
(Date:4/24/2015)... TX (PRWEB) April 24, 2015 The Fastest ... Long, after their great success of the Xtreme Fat Loss ... industry. The fat loss blueprint that claims to help ... the attention of HealthyandFitZone.com's Stan Stevenson, prompting an investigative review. ... shows that the creators spent years researching and experimenting with ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 The 1975 ... toured almost constantly across the globe to theaters, festivals and ... in Manchester, they’ve partnered with their label, Dirty Hit Records, ... Teaming up with the newly launched Cadence & Cause ... their debut LP on vinyl and a signed photo card. ...
(Date:4/24/2015)... 24, 2015 The first step to ... mind. , For meditation and yoga teacher Stine Koppernæs, ... been invaluable tools that allow her to experience more ... has been a teacher since 2006, and through the ... state of being. , “I love sharing this way ...
(Date:4/24/2015)... (PRWEB) April 24, 2015 Carinsurancequotesinfo.com has ... blog post explaining how to qualify for auto ... parents can qualify for auto insurance online, without having ... post explains that single parents can reduce their auto ... released article and properly explained. , Clients can ...
Breaking Medicine News(10 mins):Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 2Health News:Ryadon Inc. Offers Quantity Drawer Slide Discount Program Nationwide in May 2015 3Health News:Fastest Fat Loss Week Ever Review Revealed on Healthy & Fit Zone 2Health News:Internationally Recognized British Indie Rock Outfit The 1975 Partner with Cadence & Cause to Provide Clean Drinking Water to Those in Need 2Health News:Auto Insurance Discounts for Single Parents - How to Qualify for Low Rates 2
... Kennedy To Be Honored for Leadership on Right to Health , ... ... Medical School in Boston, community members and experts join for a landmark ... U.S. and Globally., The event, which commemorates World AIDS Day and the ...
... of a new initiative to create partnerships with pediatric ... has signed a memorandum of understanding with the department ... , The memorandum is the first among Mattel ... Asia and Latin America. , ...
... American application activity for individually underwritten life insurance was down ... Index (SM). Year to date (YTD) U.S. and ... months last year. November,s activity was off -0.9% as ... U.S. application activity was down -1.8% in November ...
... Christmas Story", Ralphie sets out to convince the world that a Red ... "You,ll shoot your eye out!" was the response he got ... more hilarious and memorable quotes from this Christmas classic because we,ve all ... too many people. , , It,s hard ...
... MORTON GROVE, Ill., Dec. 5 Lifeway Foods, Inc.,(Nasdaq: ... today new distribution of its 12 pack "club pack" to the ... addition to the,expansion of the Costco Midwest region from 20 stores ... of December 2008 and consumers can,expect to find the product in ...
... tumors boosts chances for those denied under current protocols, study ... patients with liver cancer who don,t meet criteria used to ... transplantation, according to an Italian study. , The Milan criteria ... 5 centimeters or less in diameter, or three or fewer ...
Cached Medicine News:Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 2Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 3Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 4Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 5Health News:Community Unites for Physicians for Human Rights Town Meeting on Global AIDS and Human Rights on December 8 6Health News:MIB Life Index Reports North American Life Insurance Activity Off 1.9% in November 2Health News:Oklahoma Parents Can Prevent Holiday Tragedies with Safe Toys and Celebrations 2Health News:Lifeway Foods Announces New East Coast and Expanded Midwest Distribution 2Health News:New Criteria Could Expand Number of Liver Transplant Candidates 2
... The unique triple-mode technology ... all-around system for an array ... technology includes a patented, controllable ... mode for classical ablation procedures, ...
... is the only in-office test approved by the ... NMP22 BladderChek Test is a painless and non-invasive ... detects elevated levels of NMP22 protein. Healthy individuals ... in the urine. However, the level of NMP22 ...
ARION is a long-pulsed alexandrite laser system with a wavelength of 755 nm...
Used for measuring rectal pressure during urodynamic studies. All-silicone construction provides maximum softness and biocompatibility for enhanced patient comfort. Supplied sterile in peel-open pack...
Medicine Products: